Meta AnalysisID 2067
血清铜与肝癌风险：一项系统评价与Meta分析
CRD42022327925
The aim of this meta-analysis is to explore whether serum copper is associated with risk of liver cancer. If the conclusion exists the relevance, what is the association between them?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2067
- Evidence Id
- 10625
- Core Evidence Id
- 10625
- Source Meta Analysis Id
- 2009
- Herb2 Meta Analysis Id
- HBMA002009
- Crd Id
- CRD42022327925
- Title
- Serum copper and risk of liver cancer: a systematic review and meta-analysis
- Review Question
- The aim of this meta-analysis is to explore whether serum copper is associated with risk of liver cancer. If the conclusion exists the relevance, what is the association between them?
- Study Type Included
- Cohort studies, case-control studies and cross-sectional studies will be included.
- Condition Being Studied
- Liver cancer has become a major public health challenge as it is the sixth most commonly diagnosed cancer and the third leading cause of cancer death worldwide in 2020, with approximately 906, 000 new cases and 830, 000 deaths. Copper is the essential trace element in the body, maintaining the living of cells. Researchers have found abnormal copper accumulation may lead to the injury of liver accompanied hepatocarcinogenesis by animal experiment. Besides, association between serum copper and liver cancer also have been reported by observational studies, but the conclusions have been inconsistent. Thus, clarifying the association between serum copper and liver cancer will help us to provide better methods for disease prevention and treatment.
- Participant
- People with information of serum copper levels and were diagnosed with liver cancer or not.
- Animal
- Human Disease Modelled
- Intervention
- Serum copper.
- Comparator Control
- People with low level of serum copper, or people had no diagnosis with liver cancer.
- Main Outcome
- Liver cancer. Measures of effect Mean with SD, SMD, OR, RR, and HR.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Copper; Humans; Liver Neoplasms; Zinc
- Contact
- Ding Ye [email protected]
- Organisational Affiliation
- Zhejiang Chinese Medical University https://www.zcmu.edu.cn
- Funding Source
- None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-04-24
- Registration Date
- 2022-05-10
- Anticipated Start Date
- 2022-04-24
- Anticipated Completion Date
- 2022-06-24
- Title Cn
- 血清铜与肝癌风险：一项系统评价与Meta分析
- Title En
- Serum copper and risk of liver cancer: a systematic review and meta-analysis
- Bilingual Status
- complete