Meta AnalysisID 2038
血清肌酐与糖尿病足溃疡风险：一项系统评价与Meta分析
CRD42022350731
Do diabetic patients (P) with altered values of creatinine (E) have more risk of diabetic foot ulcer (O) compared to normal values of creatinine (C)?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2038
- Evidence Id
- 10596
- Core Evidence Id
- 10596
- Source Meta Analysis Id
- 1981
- Herb2 Meta Analysis Id
- HBMA001981
- Crd Id
- CRD42022350731
- Title
- Serum creatinine and risk of diabetic foot ulcer : A systematic review and meta-analysis
- Review Question
- Do diabetic patients (P) with altered values of creatinine (E) have more risk of diabetic foot ulcer (O) compared to normal values of creatinine (C)?
- Study Type Included
- Case-control and cohort studies
- Condition Being Studied
- Diabetes, which is characterized by elevated blood glucose levels, is one of the most prevalent chronic metabolic diseases. In addition, it is associated with a high burden of morbidity and mortality and causes increased personal expenditure and an overload on public budgets . In 2021, the International Diabetes Federation (IDF) estimated that 536.6 million people had diabetes (10.5% of the global population) and it is estimated that about 738.2 million people (12.2%) will have this disease in 2045 . People with diabetes can develop a wide range of complications, including impaired vision from diabetic retinopathy; lower limb amputation due to diabetic foot ulcers; end-stage renal disease; and higher risk of cardiovascular diseases . Among these, the most common presentation seen in hospital admissions is diabetic foot. This complication is characterized by the association of diabetic neuropathy, and ischemia, due to peripheral arterial disease; which overall, can lead to ulceration of the foot, increased exposure to infection, and increased risk of amputation. In addition, this risk is increased by about 2 to 6 times when the diabetic patient also has end-stage renal disease.
- Participant
- Diabetic patients
- Animal
- Human Disease Modelled
- Intervention
- Altered values of creatinine
- Comparator Control
- Normal values of creatinine
- Main Outcome
- Risk of developing DFU Measures of effect OR
- Outcome Measure
- Additional Outcome
- None Measures of effect none
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Creatinine; Diabetes Mellitus; Diabetic Foot; Humans; Risk Factors; Wound Healing
- Contact
- Juan Ramiro Ulloque Badaracco [email protected]
- Organisational Affiliation
- Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Peru
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-08-01
- Registration Date
- 2022-08-12
- Anticipated Start Date
- 2022-08-01
- Anticipated Completion Date
- 2022-09-30
- Title Cn
- 血清肌酐与糖尿病足溃疡风险：一项系统评价与Meta分析
- Title En
- Serum creatinine and risk of diabetic foot ulcer : A systematic review and meta-analysis
- Bilingual Status
- complete