Meta AnalysisID 2023
成人乳糖吸收不良的国家、区域和全球估算：一项系统评价与Meta分析
CRD42017064802
The objective is to present an updated systematic review and meta-analysis on the prevalence of lactose malabsorption in geographical areas and countries, estimate the global burden, and assess variation in estimates bet
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 2023
- Evidence Id
- 10581
- Core Evidence Id
- 10581
- Source Meta Analysis Id
- 1966
- Herb2 Meta Analysis Id
- HBMA001966
- Crd Id
- CRD42017064802
- Title
- Country, regional and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis
- Review Question
- The objective is to present an updated systematic review and meta-analysis on the prevalence of lactose malabsorption in geographical areas and countries, estimate the global burden, and assess variation in estimates between different methods.
- Study Type Included
- We will evaluate studies presenting prevalence data of lactose malabsorption (LM) or lactase persistence (LP) including cross sectional and prospective studies using genotyping, hydrogen breath test (HBT), lactose tolerance test (LTT) or other methods. Studies with no prevalence data, no data on number of participants, insufficiently described methodology, or probable biased populations not representative for a general population, will be excluded.
- Condition Being Studied
- Lactose malabsorption in adults
- Participant
- Types of participants: We include studies presenting prevalence data of LM or LP among adults and excluded children under 10 years of age as LP is often lost during the first ten years. Studies using self-reported data were excluded to limit information bias. Similarly, studies including patients from in- and outpatients at gastroenterological wards will be excluded to avoid selection bias.
- Animal
- Human Disease Modelled
- Intervention
- Types of outcome measures: A range of methods for determining LM or LP will be used including genotyping, HBT, LTT and urinary galactose excretion. For genotyping, the following SNPs will be presented: LCT 13907, 13910, 13914, 13915, 14009, 14010 and 22018. A range of definitions are used for HBT including: 1.
- Comparator Control
- Main Outcome
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Adult; Breath Tests; Humans; Lactose Intolerance
- Contact
- Organisational Affiliation
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Review Stage
- First Submission Date
- Registration Date
- Anticipated Start Date
- Anticipated Completion Date
- Title Cn
- 成人乳糖吸收不良的国家、区域和全球估算：一项系统评价与Meta分析
- Title En
- Country, regional and global estimates for lactose malabsorption in adults: a systematic review and meta-analysis
- Bilingual Status
- complete