Meta AnalysisID 1940
可待因镇咳药对比安慰剂对咳嗽症状性治疗的疗效：随机对照试验的系统评价与Meta分析
CRD42019123095
Is the efficacy of treatment with codeine antitussive agents versus placebo for coughs proven by randomized controlled trials?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1940
- Evidence Id
- 10498
- Core Evidence Id
- 10498
- Source Meta Analysis Id
- 1883
- Herb2 Meta Analysis Id
- HBMA001883
- Crd Id
- CRD42019123095
- Title
- The efficacy of codeine antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials
- Review Question
- Is the efficacy of treatment with codeine antitussive agents versus placebo for coughs proven by randomized controlled trials?
- Study Type Included
- Randomized, controlled trials versus placebo trials available in French or English.
- Condition Being Studied
- Coughs, regardless of etiology.
- Participant
- People of both genders, aged > 2 years, with a cough (no restrictions on etiology).
- Animal
- Human Disease Modelled
- Intervention
- Administration of codeine antitussive agents for coughs (regardless of etiology).
- Comparator Control
- Administration of placebo.
- Main Outcome
- Cough relief, as assessed based on a binary response pattern (i.e., yes or no?).
- Outcome Measure
- Additional Outcome
- Cough relief effects on continuous outcomes (mean difference or standard mean difference): Minimal important difference; Duration of cough; Quality of life; Adverse events for example: dizziness, nausea, vomiting, drowsiness, constipation, diarrhea, hallucination, addiction; Serious adverse events (SAE); Repercussions on sleep.
- Study Method
- Intervention, Meta-analysis, Narrative synthesis, Systematic review
- Keyword
- Antitussive Agents; Codeine; Cough; Humans; Treatment Outcome
- Contact
- Maeva Maucourant [email protected]
- Organisational Affiliation
- Département de médecine générale de la Faculté Lyon EST
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English, French
- Country
- France
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-01-23
- Registration Date
- 2019-03-13
- Anticipated Start Date
- 2019-02-01
- Anticipated Completion Date
- 2019-03-01
- Title Cn
- 可待因镇咳药对比安慰剂对咳嗽症状性治疗的疗效：随机对照试验的系统评价与Meta分析
- Title En
- The efficacy of codeine antitussive agents versus placebo in symptomatic treatment of cough: a systematic review and meta-analysis of randomized controlled trials
- Bilingual Status
- complete