Meta AnalysisID 1909

关节假体钴释放相关的血液离子浓度和生物学反应:系统评价

CRD42019122301

Is wear of cobalt components from joint prosthesis related to blood ion concentration and biological reactions?

Back to Browse

Relationship Network

Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...

Record Fields

Scalar fields from the final meta_analysis record.

Meta Analysis Id
1909
Evidence Id
10467
Core Evidence Id
10467
Source Meta Analysis Id
1849
Herb2 Meta Analysis Id
HBMA001849
Crd Id
CRD42019122301
Title
Blood ion concentration and biological reactions related to cobalt release from joint prosthesis: a systematic review
Review Question
Is wear of cobalt components from joint prosthesis related to blood ion concentration and biological reactions?
Study Type Included
Inclusion: clinical trials and observational studies Exclusion: laboratory studies, reviews, conference abstracts, letters, case-reports, book chapters
Condition Being Studied
Arthroplasty related prothesis are prompted to wear due to joint movement. This wear is associated with ion release in the patient body. There is evidence suggesting that joint prosthesis with cobalt components are related to high blood ion concentration of cobalt and biological reactions due to toxicity of these ions.
Participant
Inclusion: individuals with joint arthroplasties Exclusion: individuals without joint arthroplasties
Animal
Human Disease Modelled
Intervention
Inclusion: prosthesis with cobalt components Exclusion: individual taking medications containing cobalt
Comparator Control
Inclusion: healthy individuals, prosthesis without cobalt components, or no comparison Exclusion: none
Main Outcome
Ion blood concentration and biological reactions.
Outcome Measure
Additional Outcome
Not applicable
Study Method
Meta-analysis, Prognostic, Systematic review
Keyword
Arthroplasty, Replacement; Cobalt; Humans; Joint Prosthesis
Contact
Gilberto Melo [email protected]
Organisational Affiliation
Federal University of Santa Catarina
Funding Source
Not applicable
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Discontinued
First Submission Date
2019-01-23
Registration Date
2019-02-07
Anticipated Start Date
2019-01-01
Anticipated Completion Date
2019-06-30
Title Cn
关节假体钴释放相关的血液离子浓度和生物学反应:系统评价
Title En
Blood ion concentration and biological reactions related to cobalt release from joint prosthesis: a systematic review
Bilingual Status
complete