Meta AnalysisID 1902
术前使用阿莫西林、阿莫西林/克拉维酸或克林霉素能否有效减少下颌第三磨牙手术患者的术后并发症？系统评价与Meta分析
CRD42020198794
Will preoperative administration of amoxicillin, amoxicillin/clavulanic acid, or clindamycin be effective in reducing postoperative complications in patients undergoing mandibular third molar surgery?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1902
- Evidence Id
- 10460
- Core Evidence Id
- 10460
- Source Meta Analysis Id
- 1843
- Herb2 Meta Analysis Id
- HBMA001843
- Crd Id
- CRD42020198794
- Title
- Will preoperative administration of amoxicillin, amoxicillin/clavulanic acid, or clindamycin be effective in reducing postoperative complications in patients undergoing mandibular third molar surgery? Systematic review and meta-analysis.
- Review Question
- Will preoperative administration of amoxicillin, amoxicillin/clavulanic acid, or clindamycin be effective in reducing postoperative complications in patients undergoing mandibular third molar surgery?
- Study Type Included
- Only randomized controlled clinical trials will be included.
- Condition Being Studied
- Post-surgical infection (temperature higher, purulent discharge, alveolar osteitis, swollen nodes), pain, edema and trismus after mandibular third molar surgery.
- Participant
- Patients undergoing mandibular third molar surgery (impacted and semi-impacted) will be considered.
- Animal
- Human Disease Modelled
- Intervention
- The intervention will be the preoperative administration of amoxicillin, amoxicillin/clavulanic acid or clindamycin by any route of administration and at any dose.
- Comparator Control
- The comparison group will be placebo, no treatment or any other active treatment.
- Main Outcome
- The primary result will be the evaluation of postsurgical infection (temperature higher, purulent discharge, alveolar osteitis, swollen nodes). Measures of effect The results obtained in a minimum follow-up of one week after surgery will be included.
- Outcome Measure
- Additional Outcome
- Pain (according to VAS), edema (facial contour measurements) and trismus (reduction of the mouth opening) after mandibular third molar surgery. Measures of effect The results obtained in a minimum follow-up of one week after surgery will be included.
- Study Method
- Systematic review
- Keyword
- Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clindamycin; Humans; Molar, Third; Postoperative Complications
- Contact
- Victor Chumpitaz Cerrate [email protected]
- Organisational Affiliation
- Universidad Científica del Sur, Lima, Perú
- Funding Source
- None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Peru
- Review Stage
- Review Ongoing
- First Submission Date
- 2020-07-14
- Registration Date
- 2020-08-14
- Anticipated Start Date
- 2020-07-26
- Anticipated Completion Date
- 2021-02-07
- Title Cn
- 术前使用阿莫西林、阿莫西林/克拉维酸或克林霉素能否有效减少下颌第三磨牙手术患者的术后并发症？系统评价与Meta分析
- Title En
- Will preoperative administration of amoxicillin, amoxicillin/clavulanic acid, or clindamycin be effective in reducing postoperative complications in patients undergoing mandibular third molar surgery? Systematic review and meta-analysis.
- Bilingual Status
- complete