Meta AnalysisID 1900

精氨酸和瓜氨酸对运动及恢复过程中炎症和氧化应激生物标志物的影响:系统评价与Meta分析

CRD42022359806

Investigate the involvement of arginine and citrulline on biomarkers of inflammation and oxidative stress in response to exercise.

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Record Fields

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Meta Analysis Id
1900
Evidence Id
10458
Core Evidence Id
10458
Source Meta Analysis Id
1840
Herb2 Meta Analysis Id
HBMA001840
Crd Id
CRD42022359806
Title
Influence of arginine and citrulline on biomarkers of inflammation and oxidative stress in response to physical exercise and recovery: A systematic review with meta-analysis.
Review Question
Investigate the involvement of arginine and citrulline on biomarkers of inflammation and oxidative stress in response to exercise.
Study Type Included
Randomised trials to assess the beneficial effects of the treatments
Condition Being Studied
Recovering after a physical fitness
Participant
participants older than 18 years
Animal
Human Disease Modelled
Intervention
arginine or citrulline supplementation and exercise
Comparator Control
the control group should intake placebo
Main Outcome
The studies must analyze the outcomes of oxidative stress and inflammatory markers measured before and post exercise session. Oxidative stress outcomes, the indexes included were: TBARS, Carbonyls, Uric acid (mg/dL), Malondialdehyde (MDA) (μM), Neutrophil MDA (mmol/106 cells), Creatine (CK) and lactate dehydrogenase (LDH). Regarding the outcomes for Antioxidants, we included: Superoxide dismutase (SOD) (U/mL, Catalase activity (nmol/min/mL), glutathione peroxidase (GPx).
Outcome Measure
Additional Outcome
Inflammatory we included: inter-leukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alph. Anti-inflammatory: inter-leukin-10 (IL-10). We adopted the criterion of extracting all data offered between groups in post-exercise recovery.
Study Method
Meta-analysis, Systematic review
Keyword
Arginine; Biomarkers; Citrulline; Exercise; Humans; Inflammation; Oxidative Stress
Contact
Luana Almeida Gonzaga [email protected]
Organisational Affiliation
Faculty of Science and Technology - Unesp https://www.fct.unesp.br
Funding Source
Not applied Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> Not applied
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2022-09-12
Registration Date
2022-09-23
Anticipated Start Date
2022-08-01
Anticipated Completion Date
2022-10-12
Title Cn
精氨酸和瓜氨酸对运动及恢复过程中炎症和氧化应激生物标志物的影响:系统评价与Meta分析
Title En
Influence of arginine and citrulline on biomarkers of inflammation and oxidative stress in response to physical exercise and recovery: A systematic review with meta-analysis.
Bilingual Status
complete