Meta AnalysisID 1898

口服补充L-精氨酸、L-瓜氨酸及L-精氨酸联合L-瓜氨酸对运动或身体表现的影响:系统评价

CRD42021287530

Does standalone L-arginine, standalone L-citrulline or combined L-arginine and L-citrulline oral supplementation increase nitric oxide synthesis in human participants? Does standalone L-arginine, standalone L-citrulline

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Record Fields

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Meta Analysis Id
1898
Evidence Id
10456
Core Evidence Id
10456
Source Meta Analysis Id
1838
Herb2 Meta Analysis Id
HBMA001838
Crd Id
CRD42021287530
Title
The effect of L-arginine, L-citrulline and combined L-arginine with L-citrulline oral supplementation on athletic or physical performance: systematic review
Review Question
Does standalone L-arginine, standalone L-citrulline or combined L-arginine and L-citrulline oral supplementation increase nitric oxide synthesis in human participants? Does standalone L-arginine, standalone L-citrulline or combined L-arginine and L-citrulline oral supplementation improve perceptual and physical performance in human participants?
Study Type Included
Studies that adopted randomised, double blind, placebo controlled designs with crossover.
Condition Being Studied
Fatigue during physical performance and potential nitric oxide production dysfunction.
Participant
Inclusion: Population. Studies that used human participants; sedentary, recreational active or well-trained athletes. Exclusion: non healthy human participants and animals
Animal
Human Disease Modelled
Intervention
Studies that used amino acids standalone L-arginine, standalone L-citrulline or combined both L-arginine and L-citrulline as a supplement. Supplement could be in any form, but had to be orally administered
Comparator Control
Studies that compared L-arginine and/or L-citrulline against placebo
Main Outcome
Following supplementation; Changes in plasma concentration levels of nitrate and nitrite, L-arginine and L-citrulline Changes in physical performance markers such as speed, time, power, distance, strength etc. Changes in the rate of perceived exertion
Outcome Measure
Additional Outcome
Not applicable
Study Method
Systematic review
Keyword
Arginine; Citrulline; Dietary Supplements; Humans; Physical Functional Performance; Sports
Contact
Siphamandla Nyawose [email protected]
Organisational Affiliation
University of KwaZulu Natal
Funding Source
NRF-Thuthuka Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> 129539 7 January 2021
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Australia, South Africa
Review Stage
Review Ongoing
First Submission Date
2021-10-27
Registration Date
2021-11-27
Anticipated Start Date
2021-07-29
Anticipated Completion Date
2021-12-13
Title Cn
口服补充L-精氨酸、L-瓜氨酸及L-精氨酸联合L-瓜氨酸对运动或身体表现的影响:系统评价
Title En
The effect of L-arginine, L-citrulline and combined L-arginine with L-citrulline oral supplementation on athletic or physical performance: systematic review
Bilingual Status
complete