Meta AnalysisID 1891
常用牙髓螯合剂（如依替膦酸、柠檬酸、QMix等）对根管牙本质的影响：系统评价
CRD42022308329
What is the effect of Chelating agents on radicular dentine when compared with Ethylenediaminetetraacetic acid (EDTA)?
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1891
- Evidence Id
- 10449
- Core Evidence Id
- 10449
- Source Meta Analysis Id
- 1832
- Herb2 Meta Analysis Id
- HBMA001832
- Crd Id
- CRD42022308329
- Title
- Effect of commonly used endodontic chelators (such as Etidronic acid, citric acid, QMix and others) on radicular dentine: A systematic review.
- Review Question
- What is the effect of Chelating agents on radicular dentine when compared with Ethylenediaminetetraacetic acid (EDTA)?
- Study Type Included
- Randomized controlled trials will be included in the review.
- Condition Being Studied
- The smear layer is an amorphous film that is always formed by the action of endodontic instruments inside the root canal during chemomechanical preparation. The chelating agents help in removing the smear layer, increasing the access of irrigants to allow disinfection, and also reduce microhardness. Microhardness is an indirect evidence of mineral changes in dentin. Its reduction facilitates the instrumentation throughout the canal but, it may weaken the root and increases permeability of dentin. Therefore, this systematic review focuses on finding which chelating agent will have significant effect on the radicular dentin as compared to EDTA.
- Participant
- Inclusion criteria:- a. In-vitro study b. Mature extracted teeth c. Articles reporting information about difference between various chelating agents on root dentin microhardness Exclusion Criteria:- a. Case reports, Reviews, Expert opinions to be excluded. b. Studies perform on animals, primary teeth will be excluded.
- Animal
- Human Disease Modelled
- Intervention
- Etidronic acid, maleic acid, citric acid, QMix, MTAD.
- Comparator Control
- 17% EDTA
- Main Outcome
- Effect of various chelating agents on radicular dentin will be studied. Outcomes such as microhardness and others will be evaluated.
- Outcome Measure
- Additional Outcome
- Study Method
- Systematic review
- Keyword
- Chelating Agents; Citric Acid; Dentin; Etidronic Acid; Humans; Root Canal Irrigants
- Contact
- Twinkle Talreja [email protected]
- Organisational Affiliation
- Dr DY Patil Dental College Pimpri Pune dental.dpu.edu.in
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Completed not published
- First Submission Date
- 2022-02-02
- Registration Date
- 2022-03-08
- Anticipated Start Date
- 2022-02-05
- Anticipated Completion Date
- 2022-03-05
- Title Cn
- 常用牙髓螯合剂（如依替膦酸、柠檬酸、QMix等）对根管牙本质的影响：系统评价
- Title En
- Effect of commonly used endodontic chelators (such as Etidronic acid, citric acid, QMix and others) on radicular dentine: A systematic review.
- Bilingual Status
- complete