Meta AnalysisID 1857
补充铬对心血管疾病和2型糖尿病危险因素的影响
CRD42022363706
This systematic review expects to evaluate the impacts of chromium on blood pressure, blood lipids and blood glucose in healthy populations and patients with type 2 diabetes.
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Record Fields
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- Meta Analysis Id
- 1857
- Evidence Id
- 10415
- Core Evidence Id
- 10415
- Source Meta Analysis Id
- 1800
- Herb2 Meta Analysis Id
- HBMA001800
- Crd Id
- CRD42022363706
- Title
- Chromium supplementation on risk factors of cardiovascular disease and type 2 diabetes
- Review Question
- This systematic review expects to evaluate the impacts of chromium on blood pressure, blood lipids and blood glucose in healthy populations and patients with type 2 diabetes.
- Study Type Included
- Randomized controlled trials in which placebo or controls is used as a comparison.
- Condition Being Studied
- Type 2 diabetes mellitus is a chronic systemic disease related to complications in most of the body organs. Nowadays, the prevalence of diabetes is growing worldwide. As the basic management measure of diabetes mellitus, medical nutrition therapy is increasingly used. However, the effectiveness and safety of its role need further demonstration. Chromium is an essential mineral that has required for metabolism of carbohydrates, lipids and protein through its effects on insulin sensitivity and inflammatory pathways. In regards to above functions, chromium is widely used as complementary medicine for improving metabolic disorders, such as dyslipidemia and diabetes. However, the effectiveness of chromium supplementation remains controversial. Moreover, comparison among different populations is still lacking. Therefore, we aim to perform a systematic review on the efficacy of chromium supplementations in healthy populations and patients with type 2 diabetes.
- Participant
- Healthy population or individuals with metabolic diseases, such as hypertension and type 2 diabetes.
- Animal
- Human Disease Modelled
- Intervention
- Interventions using various oral chromium supplementations, such as chromium picolinate.
- Comparator Control
- Control group, placebo and baseline to post-intervention analysis.
- Main Outcome
- 1. Blood pressure: systolic blood pressure and diastolic blood pressure. 2. Blood lipids: high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), triglyceride, and total cholesterol. 3. Blood glucose: fasting plasma glucose, fasting plasma insulin, and HbA1c.
- Outcome Measure
- Additional Outcome
- Study Method
- Meta-analysis, Systematic review
- Keyword
- Blood Glucose; Blood Pressure; Cardiovascular Diseases; Chromium; Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Lipids; Risk Factors
- Contact
- Peng An [email protected]
- Organisational Affiliation
- Department of Nutrition and Health, China Agricultural University http://dnh.cau.edu.cn
- Funding Source
- Funding from Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-09-29
- Registration Date
- 2022-10-10
- Anticipated Start Date
- 2022-10-01
- Anticipated Completion Date
- 2023-01-01
- Title Cn
- 补充铬对心血管疾病和2型糖尿病危险因素的影响
- Title En
- Chromium supplementation on risk factors of cardiovascular disease and type 2 diabetes
- Bilingual Status
- complete