Meta AnalysisID 1815

对于接受拔牙的患者,使用明胶、纤维素和/或胶原蛋白在愈合结局方面是否存在差异?

CRD42020173528

In patients that underwent dental extractions, are there differences in healing outcomes using gelatin, cellulose and/or collagen?

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Record Fields

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Meta Analysis Id
1815
Evidence Id
10373
Core Evidence Id
10373
Source Meta Analysis Id
1760
Herb2 Meta Analysis Id
HBMA001760
Crd Id
CRD42020173528
Title
In patients that underwent dental extractions, are there differences in healing outcomes using gelatin, cellulose and/or collagen?
Review Question
In patients that underwent dental extractions, are there differences in healing outcomes using gelatin, cellulose and/or collagen?
Study Type Included
We are open to other studies, however randomised control trials will be the focal point
Condition Being Studied
Patients undergoing dental extractions experience delayed healing and maybe attributable to multiple factors (eg. comorbidities, medications, trauma, infections, iatrogenic). Numerous methods have been used to promote healing. In the recent times, agents such as gelatin, cellulose, and collagen has been used with promising results. However, there has been no published systematic reviews/meta-analysis to highlight the efficacy of such agents.
Participant
Inclusion criteria: Patients that have undergone dental extractions (simple, surgical) Exclusion criteria: N/A
Animal
Human Disease Modelled
Intervention
The use of gelatin, cellulose and/or collagen that has been placed in dental extraction socket immediately post extraction.
Comparator Control
Any of the other agents (eg. plasma rich fibrin or platelets) or placebo
Main Outcome
We are assessing healing outcomes (healing time, radiographic success, clinical success where available) Measures of effect Clinical success will be based on percentages of successful healing without complications Radiographic success will be based on percentages of successful healing with radiographic evidence Risk difference will be calculated to determine the difference between two agents
Outcome Measure
Additional Outcome
N/A Measures of effect N/A
Study Method
Intervention, Meta-analysis, Systematic review
Keyword
Cellulose; Collagen; Gelatin; Humans; Tooth Extraction; Wound Healing
Contact
Magdalen Foo [email protected]
Organisational Affiliation
University of Western Australia
Funding Source
For the purpose of this review, we will be self funding
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Australia
Review Stage
Review Ongoing
First Submission Date
2020-03-13
Registration Date
2020-04-28
Anticipated Start Date
2020-03-13
Anticipated Completion Date
2021-03-13
Title Cn
对于接受拔牙的患者,使用明胶、纤维素和/或胶原蛋白在愈合结局方面是否存在差异?
Title En
In patients that underwent dental extractions, are there differences in healing outcomes using gelatin, cellulose and/or collagen?
Bilingual Status
complete