Meta AnalysisID 1809
胡萝卜和胡萝卜素与多种健康结局：一项证据的伞状综述
CRD42022340579
The associations between carrot and carotene and multiple health outcomes
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1809
- Evidence Id
- 10367
- Core Evidence Id
- 10367
- Source Meta Analysis Id
- 1754
- Herb2 Meta Analysis Id
- HBMA001754
- Crd Id
- CRD42022340579
- Title
- Carrot and carotene and multiple health outcomes: An umbrella review of the evidence
- Review Question
- The associations between carrot and carotene and multiple health outcomes
- Study Type Included
- Meta-analyses of interventional studies (randomized and nonrandomized controlled trials) and observational studies (cohort and case–control) that assessed the association of carrot and/or carotene and health-related outcomes were included regardless of ethnicity, sex and country of participants. Studies comparing the intake of carrots and/or carotene, including high versus low, placebo, and any linear or nonlinear dose–responses, were all included.
- Condition Being Studied
- Carrot is consumed widely and deeply loved by people. Carrot is recognized to have multiple beneficial effects on human health because it contains many important nutrients, including antioxidant ingredients, fiber, and vitamins. Therefore, they play an important role in maintaining health and preventing cardiovascular diseases (CVDs). Carotenes are the most important nutritional components of carrots. β-Carotene is partly directly converted into vitamin A once ingested in the intestinal tract or converted into vitamin A in the liver. It plays a vital role in maintaining the normal visual system, preventing night blindness and preserving skin health, as well as regulating certain cellular processes. Moreover, as potent antioxidants, α-carotenes and β-carotenes have been proposed to maintain health and prevent diseases such as cancer and cardiovascular disease. With the increased appreciation of health, many research studies have been conducted examining the impact of carrots/carotenes on humans. Numerous epidemiologic studies have been reported regarding the association between carrot/carotene and health outcomes, including Alzheimer’s disease (AD), fracture, various types of cancers and so on. Although a large number of meta-analyses have summarized the association between carrot/carotene and health outcomes, there remains a lack of comprehensive evidence.
- Participant
- People who intake carrots or carotenoids
- Animal
- Human Disease Modelled
- Intervention
- People who intake carrots or carotenoids. Meta-analyses of interventional studies (randomized and nonrandomized controlled trials) and observational studies (cohort and case–control) that assessed the association of carrot and/or carotene and health-related outcomes were included regardless of ethnicity, sex and country of participants. Studies comparing the intake of carrots and/or carotene, including high versus low, placebo, and any linear or nonlinear dose–responses, were all included.
- Comparator Control
- People who did not intake carrots or caeotenoids.
- Main Outcome
- Incidence of disease Measures of effect relative risks and odds ratios
- Outcome Measure
- Additional Outcome
- None Measures of effect None
- Study Method
- Review of reviews, Systematic review
- Keyword
- Carotenoids; Daucus carota; Humans; Outcome Assessment, Health Care; beta Carotene
- Contact
- Jianzhong Ai [email protected]
- Organisational Affiliation
- Department of Urology, Institute of Urology, West China Hospital, Sichuan University
- Funding Source
- grants from the National Natural Science Foundation of China (82070784, 81702536) to J. A., a grant from Science & Technology Department of Sichuan Province, China (2022JDRC0040) to J. A Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> the National Natural Science Foundation of China (82070784, 81702536) Science & Technology Department of Sichuan Province, China (2022JDRC0040)
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-06-22
- Registration Date
- 2022-07-02
- Anticipated Start Date
- 2022-06-01
- Anticipated Completion Date
- 2022-07-22
- Title Cn
- 胡萝卜和胡萝卜素与多种健康结局：一项证据的伞状综述
- Title En
- Carrot and carotene and multiple health outcomes: An umbrella review of the evidence
- Bilingual Status
- complete