Meta AnalysisID 180
睡茄（Ashwagandha）提取物单药治疗与安慰剂、常规治疗或活性对照相比对成人压力、焦虑和抑郁的影响如何？
CRD42021273565
What is the effect of 'Ashwagandha' (ASW) (Withania somnifera) extract monotherapy versus placebo or Treatment-As-Usual (TAU) or active comparator on stress, anxiety & depression among adults ?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Herb: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 180
- Evidence Id
- 8738
- Core Evidence Id
- 8738
- Source Meta Analysis Id
- 165
- Herb2 Meta Analysis Id
- HBMA000165
- Crd Id
- CRD42021273565
- Title
- What is the effect of 'Ashwagandha' (ASW) (Withania somnifera) extract monotherapy versus placebo or Treatment-As-Usual (TAU) or active comparator on stress, anxiety & depression among adults ?
- Review Question
- What is the effect of 'Ashwagandha' (ASW) (Withania somnifera) extract monotherapy versus placebo or Treatment-As-Usual (TAU) or active comparator on stress, anxiety & depression among adults ?
- Study Type Included
- Inclusion criteria : All human randomized control trials assessing the effectiveness of orally administered 'Ashwagandha' (Withania somnifera) extract as monotherapy in reducing stress, anxiety, and depression compared to placebo or TAU or active comparator shall be included in the review. Exclusion: Descriptive studies, quasi-experimental studies, narrative reviews, case reports, case series, and letters to the editor. Randomized controlled trials on patients with major mental illness will be excluded as will trials using Ashwagandha as an adjunct to psychotropic agents (antipsychotics, mood stabilizers, anti-depressants, or anti-anxiety agents).
- Condition Being Studied
- The review aims to study stress, anxiety and depression.
- Participant
- Adults having stress, anxiety & depression as measured by structured tools.
- Animal
- Human Disease Modelled
- Intervention
- The intervention involves oral administration of Ashwagandha (Withania somnifera) extract as monotherapy.
- Comparator Control
- It would include either placebo or TAU or active comparator.
- Main Outcome
- Primary outcomes(s): 'Ashwagandha' vs. placebo/TAU for reduction of stress and anxiety with Standardized mean difference (SMD) as the measure of effect size. Measures of effect Standararized Mean Difference (SMD)
- Outcome Measure
- Additional Outcome
- Secondary outcome: Ashwagandha vs. placebo/TAU for reduction of depression with SMD as the measure of effect size. Measures of effect Standarized Mean Difference
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Adult; Anxiety; Ashwagandha; Depression; Humans; Plant Extracts; Withania
- Contact
- Nitasha Sharma [email protected]
- Organisational Affiliation
- Post Graduate Institute of Medical Education & Research, Chandigarh , INDIA
- Funding Source
- NA Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> NA
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- India
- Review Stage
- Review Ongoing
- First Submission Date
- 2021-08-14
- Registration Date
- 2021-09-14
- Anticipated Start Date
- 2021-07-01
- Anticipated Completion Date
- 2021-11-30
- Title Cn
- 睡茄（Ashwagandha）提取物单药治疗与安慰剂、常规治疗或活性对照相比对成人压力、焦虑和抑郁的影响如何？
- Title En
- What is the effect of 'Ashwagandha' (ASW) (Withania somnifera) extract monotherapy versus placebo or Treatment-As-Usual (TAU) or active comparator on stress, anxiety & depression among adults ?
- Bilingual Status
- complete