Meta AnalysisID 1752
克拉维酸在儿科人群中的药代动力学与安全性：一项系统评价
CRD42020137253
Primary: Pharmacokinetics of clavulanic acid in pediatric population Secondary: Safety of clavulanic acid in pediatric population
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Record Fields
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- Meta Analysis Id
- 1752
- Evidence Id
- 10310
- Core Evidence Id
- 10310
- Source Meta Analysis Id
- 1842
- Herb2 Meta Analysis Id
- HBMA001842
- Crd Id
- CRD42020137253
- Title
- Pharmacokinetics and safety of clavulanic acid in the pediatric population: a systematic review
- Review Question
- Primary: Pharmacokinetics of clavulanic acid in pediatric population Secondary: Safety of clavulanic acid in pediatric population
- Study Type Included
- Prospective intervention studies, retrospective studies. Pharmacokinetic studies. Reference lists of review articles will be screened.
- Condition Being Studied
- Pharmacokinetics, antibiotic therapy, clinical pharmacology, pediatric infectious diseases
- Participant
- Pediatric population; 0-18 years of age including preterm and term newborns.
- Animal
- Human Disease Modelled
- Intervention
- Exposure to clavulanic acid
- Comparator Control
- Main Outcome
- Pharmacokinetic parameters: at least area under the curve (AUC), Cmax, serum concentrations. Other pk-parameters will be extracted if available (including clearance, volume of distribution, T1/2) Measures of effect Not applicable
- Outcome Measure
- Additional Outcome
- Safety: side effects, adverse events Measures of effect -
- Study Method
- Systematic review
- Keyword
- Child; Clavulanic Acid; Humans
- Contact
- Fleur Keij [email protected]
- Organisational Affiliation
- Erasmus MC-Sophia Children's Hospital www.erasmusmc.nl
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Netherlands
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-05-29
- Registration Date
- 2020-08-03
- Anticipated Start Date
- 2019-05-15
- Anticipated Completion Date
- 2020-05-01
- Title Cn
- 克拉维酸在儿科人群中的药代动力学与安全性：一项系统评价
- Title En
- Pharmacokinetics and safety of clavulanic acid in the pediatric population: a systematic review
- Bilingual Status
- complete