Meta AnalysisID 1587

镉暴露及其与肝功能异常、非酒精性脂肪性肝病和肝纤维化的关联:系统评价与Meta分析

CRD42022342690

How does cadmium exposure impact on liver function, non-alcoholic fatty liver and liver fibrosis?

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Record Fields

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Meta Analysis Id
1587
Evidence Id
10145
Core Evidence Id
10145
Source Meta Analysis Id
1542
Herb2 Meta Analysis Id
HBMA001542
Crd Id
CRD42022342690
Title
Exposure to Cadmium and its Association with Abnormal Liver function, NAFLD and Liver Fibrosis: A Systematic Review and Meta-Analysis
Review Question
How does cadmium exposure impact on liver function, non-alcoholic fatty liver and liver fibrosis?
Study Type Included
We will include cohort and cross-sectional studies
Condition Being Studied
Abnormal ALT, AST; Non-alcoholic fatty liver; Liver fibrosis in adults.
Participant
Inclusion: Adults without liver virus infection.
Animal
Human Disease Modelled
Intervention
Cadmium exposure comes from dietary or drinking water that contains cadmium or from smoking cigarettes.
Comparator Control
Not applicable
Main Outcome
The cadmium exposure is positively related to abnormal liver function, NAFLD and liver fibrosis. Measures of effect Odds ratios, beta value.
Outcome Measure
Additional Outcome
Not applicable
Study Method
Meta-analysis, Systematic review
Keyword
Cadmium; Humans; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Risk Factors
Contact
Jiahao Xu [email protected]
Organisational Affiliation
the Third Xiangya Hospital
Funding Source
The National Natural Science Foundation of China (81670504 and 81970494) and the Hunan Province Key R&D Area Planned Projects (905212456082)
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2022-06-27
Registration Date
2022-07-08
Anticipated Start Date
2022-06-22
Anticipated Completion Date
2022-07-27
Title Cn
镉暴露及其与肝功能异常、非酒精性脂肪性肝病和肝纤维化的关联:系统评价与Meta分析
Title En
Exposure to Cadmium and its Association with Abnormal Liver function, NAFLD and Liver Fibrosis: A Systematic Review and Meta-Analysis
Bilingual Status
complete