Meta AnalysisID 1569

丁苯酞辅助治疗血管性痴呆的疗效与安全性:系统评价与Meta分析方案

CRD42020168947

What is the efficacy and safety of butylphthalide as adjunctive therapy for vascular dementia?

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Record Fields

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Meta Analysis Id
1569
Evidence Id
10127
Core Evidence Id
10127
Source Meta Analysis Id
1523
Herb2 Meta Analysis Id
HBMA001523
Crd Id
CRD42020168947
Title
Efficacy and safety of butylphthalide as adjunctive therapy for vascular dementia: a protocol for systematic review and meta-analysis
Review Question
What is the efficacy and safety of butylphthalide as adjunctive therapy for vascular dementia?
Study Type Included
Only controlled randomized trials will be included.
Condition Being Studied
Vascular dementia
Participant
Inclusion: Adults with vascular dementia (as diagnosed using any recognized criteria). Exclusion: patients with an expecting life time less than 6 months.
Animal
Human Disease Modelled
Intervention
Vascular dementia patients treated by butylphthalide and conventional therapy. There is no restriction regarding the formulation of butylphthalide used.
Comparator Control
Vascular dementia patients treated by conventional therapy.
Main Outcome
Mini-mental state examination (MMSE) score. Activities of daily living (ADL) score. Adverse event rate. Measures of effect Last available follow-up of the original study.
Outcome Measure
Additional Outcome
Barthel index. Measures of effect Last available follow-up of the original study.
Study Method
Meta-analysis, Systematic review
Keyword
3-n-butylphthalide; Benzofurans; Combined Modality Therapy; Dementia; Dementia, Vascular; Humans
Contact
Ling Zhou [email protected]
Organisational Affiliation
Zhoushan Hospital, Zhoushan China
Funding Source
Science and technology administration of Zhoushan, China (2018C31112)
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
China
Review Stage
Review Ongoing
First Submission Date
2020-02-12
Registration Date
2020-04-28
Anticipated Start Date
2020-04-01
Anticipated Completion Date
2020-12-31
Title Cn
丁苯酞辅助治疗血管性痴呆的疗效与安全性:系统评价与Meta分析方案
Title En
Efficacy and safety of butylphthalide as adjunctive therapy for vascular dementia: a protocol for systematic review and meta-analysis
Bilingual Status
complete