Meta AnalysisID 1545
多氯联苯暴露与子宫内膜异位症风险：一项系统评价方案
CRD42019120539
Is polychlorinated biphenyl exposure a risk factor for endometriosis?
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Record Fields
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- Meta Analysis Id
- 1545
- Evidence Id
- 10103
- Core Evidence Id
- 10103
- Source Meta Analysis Id
- 1500
- Herb2 Meta Analysis Id
- HBMA001500
- Crd Id
- CRD42019120539
- Title
- Polychlorinated biphenyl exposure and the risk of endometriosis: a systematic review protocol
- Review Question
- Is polychlorinated biphenyl exposure a risk factor for endometriosis?
- Study Type Included
- We will select all studies which have defined PCB exposure and endometriosis risk. All retrospective and prospective observational studies, including cross-sectional designs, traditional case-control designs, prospective case-control designs (case-cohort/nested case-control studies) and different cohort designs will be included in our systematic review and meta-analysis. Case reports, case series studies, in vitro studies, and animal studies will be excluded.
- Condition Being Studied
- Polychlorinated biphenyl exposure and endometriosis (endometriosis is a gynecological disorder that is increasing in prevalence, although its etiology is unclear).
- Participant
- Endometriosis patients (with the severity of endometriosis I, II, III, IV) aged 18-49 years, with a diagnosis of endometriosis confirmed by laparoscopy.
- Animal
- Human Disease Modelled
- Intervention
- Polychlorinated biphenyl exposure and the risk of endometriosis. The exposure/risk factor will be analyzed by gas chromatography (GC) or gas chromatography-mass spectrometry (GC-MS). As such, we will select all primary studies which used these methods for PCBs measurement in blood and serum. All observational studies not using the GC or GC-MS method will be excluded.
- Comparator Control
- None.
- Main Outcome
- Endometriosis.
- Outcome Measure
- Additional Outcome
- Stage of endometriosis.
- Study Method
- Epidemiologic, Systematic review
- Keyword
- Endometriosis; Environmental Exposure; Environmental Pollutants; Female; Humans; Polychlorinated Biphenyls; Risk; Risk Factors; Uterus
- Contact
- Parvaneh Mirabi [email protected]
- Organisational Affiliation
- Infertility and Reproductive Health Research Center
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Iran
- Review Stage
- Review Ongoing
- First Submission Date
- 2019-01-05
- Registration Date
- 2019-01-22
- Anticipated Start Date
- 2018-10-01
- Anticipated Completion Date
- 2019-06-30
- Title Cn
- 多氯联苯暴露与子宫内膜异位症风险：一项系统评价方案
- Title En
- Polychlorinated biphenyl exposure and the risk of endometriosis: a systematic review protocol
- Bilingual Status
- complete