Meta AnalysisID 1527

摄入β-葡聚糖对食欲和饱腹感影响的系统评价

CRD42015023989

Does intake of ß-glucans influence markers of appetite and satiety in healthy adults?

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Record Fields

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Meta Analysis Id
1527
Evidence Id
10085
Core Evidence Id
10085
Source Meta Analysis Id
1482
Herb2 Meta Analysis Id
HBMA001482
Crd Id
CRD42015023989
Title
A systematic review on the effects of intake of beta-glucan on appetite and satiety
Review Question
Does intake of ß-glucans influence markers of appetite and satiety in healthy adults?
Study Type Included
Acute and chronic randomised controlled trials in humans. Both parallel and crossover studies will be considered suitable. Evidence from acute and chronic studies will be considered separately. Observational and animal studies will be excluded.
Condition Being Studied
Measures of appetite and satiety including ad libitum energy intake, subjective appetite ratings (hunger, fullness, desire to eat) and selected gut hormones (PYY, CCK, GLP-1).
Participant
Inclusion – Healthy adults (aged 18-65 years) of any gender that are normal weight, overweight or obese, including those with hyperlipidaemia. Exclusion – Children, adolescents (age <18 years) or older adults (aged >65 years). Subjects with reported chronic diseases such as cancer and type 2 diabetes.
Animal
Human Disease Modelled
Intervention
Beta-glucans from various sources (oats, barley, supplements). Any interventions which are concurrent with other interventions (e.g. beta-glucan plus another fibre) will not be considered to be suitable for inclusion.
Comparator Control
An appropriate control food is similar to the intervention but does not contain any ß-glucan or other soluble fibre. The control could include an insoluble fibre. Comparison with other types of soluble fibres will be excluded.
Main Outcome
Energy intake Measures of effect Can include energy intake from acute ad libitum meals and mean 24-h intake
Outcome Measure
Additional Outcome
Subjective appetite measure assessed using Visual Analogue Scale ratings or equivalent for variable such as hunger, fullness and desire to eat Plasma gut hormones: peptide YY, cholecystokinin and glucagon-like peptide 1
Study Method
Keyword
Appetite; beta-Glucans; Humans; Satiation; Satiety Response;
Contact
Dr Darzi [email protected]
Organisational Affiliation
King's College London
Funding Source
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
England
Review Stage
Review Ongoing
First Submission Date
Registration Date
2015-06-29
Anticipated Start Date
2015-05-18
Anticipated Completion Date
2015-12-31
Title Cn
摄入β-葡聚糖对食欲和饱腹感影响的系统评价
Title En
A systematic review on the effects of intake of beta-glucan on appetite and satiety
Bilingual Status
complete