Meta AnalysisID 152

茶(茶树)或其生物活性成分L-茶氨酸或L-茶氨酸联合咖啡因对健康人群认知、睡眠和情绪的影响:一项系统评价

CRD42022351601

What is the effect of tea derived from Camellia sinensis, L-theanine, or L-theanine plus caffeine, but not solely caffeine, compared to a control, on cognition, sleep, and mood in apparently healthy human participants pa

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Record Fields

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Meta Analysis Id
152
Evidence Id
8710
Core Evidence Id
8710
Source Meta Analysis Id
138
Herb2 Meta Analysis Id
HBMA000138
Crd Id
CRD42022351601
Title
The effects of tea (Camellia sinensis) or its bioactive compounds L-theanine or L-theanine plus caffeine on cognition, sleep, and mood in apparently healthy subjects: a systematic review
Review Question
What is the effect of tea derived from Camellia sinensis, L-theanine, or L-theanine plus caffeine, but not solely caffeine, compared to a control, on cognition, sleep, and mood in apparently healthy human participants participating in randomized controlled trials?
Study Type Included
Only randomised controlled trials will be included. Systematic reviews, meta-analyses, and abstracts, exposure, in vitro, in silico, observational, animal, and case studies will be excluded. Within-subject trials/crossover trials and parallel group trials will be included.
Condition Being Studied
Our systematic review will focus on human cognitive function, sleep, and mood.
Participant
We will include data obtained in apparently healthy participants of any age. We will include studies of participants with ADHD or autism. We will exclude studies of participants with severe clinical symptoms of depression, schizophrenia, mental health disorders, Alzheimer’s, dementia, or anything that requires institutionalisation or intensive pharmacological intervention that would be expected to interfere with the primary outcome(s). We will exclude studies in which the participants did not attain a normal score on a neurological questionnaire.
Animal
Human Disease Modelled
Intervention
Studies using interventions that include tea, green tea, black tea, theanine, L-theanine, γ-glutamylethylamide, g-glutamylethylamide, Camellia sinensis or Camelia sinensis will be considered. Any intervention in which the effects of tea cannot be disentangled from the control/comparator will not be considered. Interventions that include common tea additives such as milk and sugar will be considered. Interventions of any dose, form, or duration will be considered. Interventions that only contain caffeine, polyphenols, flavonoids, or catechins, or any combination, will be excluded.
Comparator Control
Studies will only be considered if they include a control and/or placebo treatment. Multiple controls will be considered, for example, water (temperature-matched, tap, mineral, caffeine-matched), coffee, or caffeine.
Main Outcome
The main outcomes will be cognition, sleep, and/or mood.
Outcome Measure
Additional Outcome
Study Method
Meta-analysis, Systematic review
Keyword
Caffeine; Camellia sinensis; Cognition; Healthy Volunteers; Humans; Sleep; Tea; theanine
Contact
Edward Payne [email protected]
Organisational Affiliation
University of Aberdeen ekaterra https://www.abdn.ac.uk/
Funding Source
ekaterra Research & Development UK Limited
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Scotland
Review Stage
Review Ongoing
First Submission Date
2022-08-05
Registration Date
2022-08-17
Anticipated Start Date
2022-08-05
Anticipated Completion Date
2022-12-31
Title Cn
茶(茶树)或其生物活性成分L-茶氨酸或L-茶氨酸联合咖啡因对健康人群认知、睡眠和情绪的影响:一项系统评价
Title En
The effects of tea (Camellia sinensis) or its bioactive compounds L-theanine or L-theanine plus caffeine on cognition, sleep, and mood in apparently healthy subjects: a systematic review
Bilingual Status
complete