Meta AnalysisID 1460
阿托品对近视儿童脉络膜厚度的影响：一项Meta分析
CRD42022381195
The purpose of this meta-analysis of randomized controlled trials was to evaluate the effect of atropine on choroidal thickness in myopia.
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Record Fields
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- Meta Analysis Id
- 1460
- Evidence Id
- 10018
- Core Evidence Id
- 10018
- Source Meta Analysis Id
- 1414
- Herb2 Meta Analysis Id
- HBMA001414
- Crd Id
- CRD42022381195
- Title
- Effects of atropine on choroidal thickness in myopic children: A Meta-Analysis
- Review Question
- The purpose of this meta-analysis of randomized controlled trials was to evaluate the effect of atropine on choroidal thickness in myopia.
- Study Type Included
- Randomized control trials (RCTs) and cohort studies on the relevant topic were selected.
- Condition Being Studied
- Myopia is the most common eye disease in the world. In the past few decades, the prevalence of myopia has increased dramatically, becoming a serious worldwide public health problem. It is expected to affect 4.8 billion people globally by 2050, which means that within 30 years, 50% of the world's population will be nearsighted. The prevalence of myopia in Asia, at 80 percent or higher, has reached pandemic levels.
- Participant
- The participants were school-age children with myopia, aged 6–18 years old were included.
- Animal
- Human Disease Modelled
- Intervention
- Atropine was used in at least 1 treatment arm.
- Comparator Control
- The control group was not treated with atropine.
- Main Outcome
- The weighted mean differences (WMDs) and 95% confidence intervals (CIs) were calculated for each study to assess choroidal thickness changes between the two groups (intervention and control). The absolute changes (Means and standard deviations) in choroidal thickness, AL and SER were used to calculate the WMDs. Measures of effect weighted mean differences (WMDs).
- Outcome Measure
- Additional Outcome
- axial length, spherical equivalent refractive. Measures of effect weighted mean differences (WMDs).
- Study Method
- Keyword
- Atropine; Child; Humans; Myopia, Degenerative; Randomized Controlled Trials as Topic
- Contact
- Yaqi Yang [email protected]
- Organisational Affiliation
- ChangChun University of Traditional Chinese Medicine
- Funding Source
- ilin Provincial Natural Science Foundation (Grant No.202512JC010477466).
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-12-03
- Registration Date
- 2022-12-14
- Anticipated Start Date
- 2022-12-01
- Anticipated Completion Date
- 2023-01-01
- Title Cn
- 阿托品对近视儿童脉络膜厚度的影响：一项Meta分析
- Title En
- Effects of atropine on choroidal thickness in myopic children: A Meta-Analysis
- Bilingual Status
- complete