Meta AnalysisID 1457
三种浓度阿托品、户外活动与健康教育对儿童和青少年近视控制的有效性：一项网状Meta分析
CRD42022369896
Our aim is to compare the effectiveness of three atropine concentrations, outdoor activity and health education for myopia control in children and adolescents
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Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1457
- Evidence Id
- 10015
- Core Evidence Id
- 10015
- Source Meta Analysis Id
- 1411
- Herb2 Meta Analysis Id
- HBMA001411
- Crd Id
- CRD42022369896
- Title
- Effectiveness of three atropine concentrations, outdoor activity and health education for myopia control in children and adolescents: a network meta-analysis
- Review Question
- Our aim is to compare the effectiveness of three atropine concentrations, outdoor activity and health education for myopia control in children and adolescents
- Study Type Included
- We will only consider randomized controlled trials (RCTs). The studies were selected according to the following criteria: (1) including trials if intervention duration was at least 12 months, (2) excluding nonrandomized or noncomparative study, (3) excluding trails if not having required outcome measures or failing to provide data suitable for meta-analysis, (4) excluding trials if the mean spherical equivalent error of participants was more than 0.25 D myopic refraction
- Condition Being Studied
- It was estimated that half of the global population will be myopic by 2050. Myopia has been a major global public health concern not only for its high prevalence but also for its potential serious complications including macular degeneration, glaucoma, cataracts, vitreous opacity, and retinal detachment. Atropine is one of the most widely used agents of pharmacologic intervention for myopia. Some group-based interventions like increased outdoor activity and health education have emerged in recent years and proven to be effective in myopia prevention and control among children and adolescents. However, there is a lack of evidence to compare the effectiveness of atropine, health education and increased outdoor activity in myopia control among those without serious myopia condition.
- Participant
- we will include participants aged less than 18 years
- Animal
- Human Disease Modelled
- Intervention
- Low-dose atropine (0.01%) Moderate-dose atropine (>0.01% to<0.5%) High-dose atropine (0.5-1.0%) Increased outdoor activity Health education
- Comparator Control
- each intervention listed in the intervention, exposure section will be compared with one another
- Main Outcome
- Mean annual change in refractions (diopters/year) and mean annual change in axial length (millimeters/year) Measures of effect mean difference, 95% CrI
- Outcome Measure
- Additional Outcome
- incident myopia, adverse outcomes Measures of effect relative risks (RR)
- Study Method
- Intervention, Network meta-analysis, Systematic review
- Keyword
- Humans
- Contact
- Lan Guo [email protected]
- Organisational Affiliation
- sun yat-sen university
- Funding Source
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-10-26
- Registration Date
- 2022-11-06
- Anticipated Start Date
- 2022-10-01
- Anticipated Completion Date
- 2022-12-24
- Title Cn
- 三种浓度阿托品、户外活动与健康教育对儿童和青少年近视控制的有效性：一项网状Meta分析
- Title En
- Effectiveness of three atropine concentrations, outdoor activity and health education for myopia control in children and adolescents: a network meta-analysis
- Bilingual Status
- complete