Meta AnalysisID 1321
赤藓糖醇、甘氨酸和海藻糖作为龈下空气抛光粉对非手术牙周治疗的临床效果比较：随机临床试验的网状Meta分析
CRD42022366792
What are the different effects of erythritol，glycine and trehalose as subgingival air polishing powder on nonoperative periodontal treatment？
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Record Fields
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- Meta Analysis Id
- 1321
- Evidence Id
- 9879
- Core Evidence Id
- 9879
- Source Meta Analysis Id
- 1282
- Herb2 Meta Analysis Id
- HBMA001282
- Crd Id
- CRD42022366792
- Title
- Comparative Clinical Effects of Erythritol，Glycine and Trehalose as Subgingival Air Polishing Powders on Non-operative Periodontal Treatment：A Network Meta- Analysis of Randomized Clinical Trial
- Review Question
- What are the different effects of erythritol，glycine and trehalose as subgingival air polishing powder on nonoperative periodontal treatment？
- Study Type Included
- Randomized controlled trials (RCTs) will be included.
- Condition Being Studied
- Periodontal disease is an inflammatory and destructive disease involving four kinds of periodontal supporting tissues. It is caused by the immune inflammatory response of the gingiva caused by dental plaque, leading to the destruction of the periodontal attachment structure. Plaque control is a necessary measure for the prevention and treatment of periodontal disease, which is the focus of the basic treatment of periodontal disease. Subgingival curettage is performed by using a fine subgingival curettage device to locate the calculus and plaque on the root surface of the periodontal pocket. Glycine powder is biocompatible and can remove subgingival biofilm with less wear on root cementum and dentin. Erythritol is water-soluble and chemically stable. It is used as a food additive and artificial sweetener worldwide. It is suitable for air polishing and can effectively remove subgingival biofilms on root surfaces, and can bring patients a comfortable experience. Trehalose, a non-cariogenic disaccharide approved for food processing, has an abrasive effect on dental material similar to glycine.
- Participant
- Randomized controlled trials that enrolled patients in good general health, over 18 years of age, probing depth of more than 4mm, without implants and requiring treatment for periodontal disease. They had undergone periodontal treatment with subgingival air polishing and were followed up for 6 weeks or more.
- Animal
- Human Disease Modelled
- Intervention
- Non-surgical periodontal treatment with subgingival air polishing was used, including hand and ultrasonic subgingival scaling. Air polished powders include erythritol, glycine and trehalose.
- Comparator Control
- No periodontitis treatment or a delayed treatment equal to that provided to the test group after the study period of follow-up.
- Main Outcome
- Probing depth(PD) , clinical attachment level (CAL) and bleeding on probing(BOP). Measures of effect Standard Mean Difference/Mean Difference
- Outcome Measure
- Additional Outcome
- Subgingival microbial mass Measures of effect Standard Mean Difference/Mean Difference
- Study Method
- Intervention, Meta-analysis, Systematic review
- Keyword
- Erythritol; Glycine; Humans; Periodontal Pocket; Powders; Trehalose
- Contact
- Zile Yuan [email protected]
- Organisational Affiliation
- Xiangya Stomatological Hospital https://xykqyy.csu.edu.cn/
- Funding Source
- None Grant number(s) <span style=font-size: 14px>State the funder, grant or award number and the date of award</span> None
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- China
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-10-12
- Registration Date
- 2022-10-24
- Anticipated Start Date
- 2022-09-01
- Anticipated Completion Date
- 2023-03-01
- Title Cn
- 赤藓糖醇、甘氨酸和海藻糖作为龈下空气抛光粉对非手术牙周治疗的临床效果比较：随机临床试验的网状Meta分析
- Title En
- Comparative Clinical Effects of Erythritol，Glycine and Trehalose as Subgingival Air Polishing Powders on Non-operative Periodontal Treatment：A Network Meta- Analysis of Randomized Clinical Trial
- Bilingual Status
- complete