Meta AnalysisID 1276
甲状腺切除术患者术前给予维生素D和钙剂以预防低钙血症：随机对照试验的系统评价与Meta分析
CRD42022356363
Does preoperative vitamin D and calcium administration reduce the risk of hypocalcemia following total or partial thyroidectomy?
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Ingredient: 1Meta-analysis: 1Links: 1
Arranging relationship network...
Record Fields
Scalar fields from the final meta_analysis record.
- Meta Analysis Id
- 1276
- Evidence Id
- 9834
- Core Evidence Id
- 9834
- Source Meta Analysis Id
- 1238
- Herb2 Meta Analysis Id
- HBMA001238
- Crd Id
- CRD42022356363
- Title
- Pre-operative Vitamin D and Calcium administration in patients undergoing thyroidectomy to prevent hypocalcemia: a systematic review and meta-analysis of Randomized controlled trials.
- Review Question
- Does preoperative vitamin D and calcium administration reduce the risk of hypocalcemia following total or partial thyroidectomy?
- Study Type Included
- Randomized controlled trials (RCTs)
- Condition Being Studied
- Hypocalcemia is a state of low serum calcium levels, it is caused by several etiologies such as Vitamin D deficiency, hypoparathyroidism, and chronic kidney disease. Thyroidectomy is one of the causes of transient/permanent postoperative hypoparathyroidism leading to hypocalcemia.
- Participant
- Adult patients 18 years or older undergoing thyroidectomy exclusion: under 18 and revision surgery
- Animal
- Human Disease Modelled
- Intervention
- pre-operative Vitamin D and calcium supplementation
- Comparator Control
- Placebo or nothing
- Main Outcome
- Primary endpoint is to compare post-operative calcium based on either clinical symptoms or laboratory values in all groups, the groups received Vitamin D only or Vitamin D with calcium and the group received placebo or nothing. Measures of effect Continuous outcomes will be presented as mean difference Dichotomous outcomes will be presented as risk ratio
- Outcome Measure
- Additional Outcome
- secondary outcomes are incidence of permanent hypoparathyroidism and the length hospital stay. Measures of effect Continuous outcomes will be presented as mean difference Dichotomous outcomes will be presented as risk ratio
- Study Method
- Intervention, Meta-analysis, Prevention, Systematic review
- Keyword
- Calcium; Humans; Hypocalcemia; Randomized Controlled Trials as Topic; Thyroidectomy; Vitamin D
- Contact
- Mohammed Alhakami [email protected]
- Organisational Affiliation
- College of Medicine, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Jeddah, Saudi Arabia
- Funding Source
- No funding
- Other Selection Criteria
- Final Publication
- Same Topic Review
- Published Protocol
- Review Type
- Language
- English
- Country
- Saudi Arabia
- Review Stage
- Review Ongoing
- First Submission Date
- 2022-09-01
- Registration Date
- 2022-09-12
- Anticipated Start Date
- 2022-09-12
- Anticipated Completion Date
- 2023-03-12
- Title Cn
- 甲状腺切除术患者术前给予维生素D和钙剂以预防低钙血症：随机对照试验的系统评价与Meta分析
- Title En
- Pre-operative Vitamin D and Calcium administration in patients undergoing thyroidectomy to prevent hypocalcemia: a systematic review and meta-analysis of Randomized controlled trials.
- Bilingual Status
- complete