Meta AnalysisID 1151

硅酸钙基与环氧树脂基封闭剂的细胞毒性和遗传毒性是否相当?一项体外研究的系统评价

CRD42020219152

Do calcium silicate-based sealers have cytotoxicity and genotoxicity comparable to epoxy resin-based sealers?

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Record Fields

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Meta Analysis Id
1151
Evidence Id
9709
Core Evidence Id
9709
Source Meta Analysis Id
1117
Herb2 Meta Analysis Id
HBMA001117
Crd Id
CRD42020219152
Title
Are the cytotoxicity and genotoxicity of calcium silicate-based and epoxy resin-based sealers comparable? A systematic review of in vitro studies
Review Question
Do calcium silicate-based sealers have cytotoxicity and genotoxicity comparable to epoxy resin-based sealers?
Study Type Included
Only in vitro studies that compared the cytotoxicity and/or genotoxicity of calcium silicate-based and epoxy resin-based sealers
Condition Being Studied
Cytotoxicity and/or genotoxicity. Calcium silicate-based and epoxy resin-based sealers.
Participant
Cell models (in vitro studies)
Animal
Human Disease Modelled
Intervention
Calcium silicate-based sealer specimens
Comparator Control
Epoxy resin-based sealer specimens
Main Outcome
Cell viability and/or proliferation (cytotoxicity); Micronuclei formation, foci formation and/or DNA damage (genotoxicity) Measures of effect -
Outcome Measure
Additional Outcome
- Measures of effect -
Study Method
Systematic review
Keyword
Epoxy Resins; Humans; Silicates; calcium silicate
Contact
Theodoro Weissheimer [email protected]
Organisational Affiliation
Federal University of Rio Grande do Sul
Funding Source
No fundings or sponsors will participate in this research.
Other Selection Criteria
Final Publication
Same Topic Review
Published Protocol
Review Type
Language
English
Country
Brazil
Review Stage
Review Ongoing
First Submission Date
2020-11-05
Registration Date
2020-12-06
Anticipated Start Date
2020-11-05
Anticipated Completion Date
2021-04-30
Title Cn
硅酸钙基与环氧树脂基封闭剂的细胞毒性和遗传毒性是否相当?一项体外研究的系统评价
Title En
Are the cytotoxicity and genotoxicity of calcium silicate-based and epoxy resin-based sealers comparable? A systematic review of in vitro studies
Bilingual Status
complete