IngredientID 19

20(s)--protopanoxadiol

C38H47N5O5

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Herb: 1Ingredient: 1Target: 2Links: 3
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Record Fields

Scalar fields from the final ingredient record.

Ingredient Id
19
Core Entity Id
198
Source Entity Count
1
Preferred Name
20(s)--protopanoxadiol
Name En
Pubchem Id
5481990
Smiles Canonical
CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6
Molecular Formula
C38H47N5O5
Molecular Weight
653.8240
Inchikey
UBUFVRJUGFJQSI-PPJSLLJVSA-N
Inchi
InChI=1S/C38H47N5O5/c1-38(2,3)41-36(47)32-24-42(22-26-18-28-13-16-48-37(28)39-21-26)14-15-43(32)23-30(44)19-29(17-25-9-5-4-6-10-25)35(46)40-34-31-12-8-7-11-27(31)20-33(34)45/h4-13,16,18,21,29-30,32-34,44-45H,14-15,17,19-20,22-24H2,1-3H3,(H,40,46)(H,41,47)/t29-,30+,32+,33-,34+/m1/s1
Isomeric Smiles
CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6
Cas Id
Ob Score
Mol Logp
3.6131
Num H Donors
4
Num H Acceptors
8
Num Rotatable Bonds
11
Drug Likeness
0.1930
Polar Surface Area
Molecular Volume
Alogp

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
20(S)--protopanoxadiol
Role
preferred
Source
TCMBank
Preferred
Yes
Name
20(s)--protopanoxadiol
Role
preferred
Source
itcmdb_public
Preferred
Yes
Name
20(s)--protopanoxadiol
Role
preferred
Source
HERB_v2
Preferred
Yes
Name
(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide
Role
alias
Source
HERB_v2
Preferred
No
Name
(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide
Role
alias
Source
itcmdb_public
Preferred
No
Name
1-Piperazinepentanamide, N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(((1,1-dimethylethyl)amino)carbonyl)-4-(furo(2,3-b)pyridin-5-ylmethyl)-gamma-hydroxy-alpha-(phenylmethyl)-, (alphaR,gammaS,2S)-
Role
alias
Source
itcmdb_public
Preferred
No
Name
1-Piperazinepentanamide, N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(((1,1-dimethylethyl)amino)carbonyl)-4-(furo(2,3-b)pyridin-5-ylmethyl)-gamma-hydroxy-alpha-(phenylmethyl)-, (alphaR,gammaS,2S)-
Role
alias
Source
HERB_v2
Preferred
No
Name
160729-91-9
Role
alias
Source
HERB_v2
Preferred
No
Name
160729-91-9
Role
alias
Source
itcmdb_public
Preferred
No
Name
CHEMBL2062137
Role
alias
Source
HERB_v2
Preferred
No
Name
CHEMBL2062137
Role
alias
Source
itcmdb_public
Preferred
No
Name
CompoundK
Role
alias
Source
itcmdb_public
Preferred
No
Name
CompoundK
Role
alias
Source
HERB_v2
Preferred
No
Name
D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(furo[2,3-b]pyridin-5-ylmethyl)-1-piperazinyl]-2-(phenylmethyl)-
Role
alias
Source
HERB_v2
Preferred
No
Name
D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(furo[2,3-b]pyridin-5-ylmethyl)-1-piperazinyl]-2-(phenylmethyl)-
Role
alias
Source
itcmdb_public
Preferred
No
Name
HIV-IN-11
Role
alias
Source
HERB_v2
Preferred
No
Name
HIV-IN-11
Role
alias
Source
itcmdb_public
Preferred
No
Name
L 754394
Role
alias
Source
HERB_v2
Preferred
No
Name
L 754394
Role
alias
Source
itcmdb_public
Preferred
No

Aliases

Additional names normalized into the restored final schema.

(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide1-Piperazinepentanamide, N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(((1,1-dimethylethyl)amino)carbonyl)-4-(furo(2,3-b)pyridin-5-ylmethyl)-gamma-hydroxy-alpha-(phenylmethyl)-, (alphaR,gammaS,2S)-160729-91-9CHEMBL2062137CompoundKD-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(furo[2,3-b]pyridin-5-ylmethyl)-1-piperazinyl]-2-(phenylmethyl)-HIV-IN-11L 754394

Cross References

Trusted external identifiers retained for this final record.

Herb
HBIN003513
Npass
NPC75179
Tcmid
42798
Pub Chem
5481990
Tcmbank
TCMBANKIN026308

Attributes

Merged source attributes and domain-specific metadata.

In Ch I
InChI=1S/C38H47N5O5/c1-38(2,3)41-36(47)32-24-42(22-26-18-28-13-16-48-37(28)39-21-26)14-15-43(32)23-30(44)19-29(17-25-9-5-4-6-10-25)35(46)40-34-31-12-8-7-11-27(31)20-33(34)45/h4-13,16,18,21,29-30,32-34,44-45H,14-15,17,19-20,22-24H2,1-3H3,(H,40,46)(H,41,47)/t29-,30+,32+,33-,34+/m1/s1
Mol Wt
653.824
Smiles
CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6
Mol Log P
3.613100000000005
In Ch Ikey
UBUFVRJUGFJQSI-PPJSLLJVSA-N
Num Hdonors
4
Drug Likeness
0.193
Num Hacceptors
8
Isomeric Smiles
CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6
Canonical Smiles
CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=C6C(=C5)C=CO6
Herb Alias Names
160729-91-9L 754394L-754394L-754,394HIV-IN-11CHEMBL2062137(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino]-5-oxopentyl]-N-tert-butyl-4-(furo[2,3-b]pyridin-5-ylmethyl)piperazine-2-carboxamide1-Piperazinepentanamide, N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(((1,1-dimethylethyl)amino)carbonyl)-4-(furo(2,3-b)pyridin-5-ylmethyl)-gamma-hydroxy-alpha-(phenylmethyl)-, (alphaR,gammaS,2S)-D-erythro-Pentonamide, 2,3,5-trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(furo[2,3-b]pyridin-5-ylmethyl)-1-piperazinyl]-2-(phenylmethyl)-CompoundK
Molecular Formula
C38H47N5O5
Molecular Formula
C38H47N5O5
Num Rotatable Bonds
11