DiseaseID 954

卵巢早衰

disease

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Disease: 1Symptom: 2Target: 12Links: 14

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Record Fields

Scalar fields from the final disease record.

Disease Id: 954
Core Entity Id: 1079
Source Entity Count: 1
Preferred Name: Ovarian Failure, Premature
Name Cn: 卵巢早衰
Name Pinyin: Luan Chao Zao Shuai
Name En: Premature Ovarian Failure
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Do Class: disease of anatomical entity
Hpo Class
Mesh Class Name: Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Hpo Class Name
Do Class Name: disease of anatomical entity
Disease Definition: NCI2016_NICHD_1602D:Absent or premature cessation of ovarian function due to an issue originating within the ovaries.|NCI2016_NCI-GLOSS_1602D:A condition in which the ovaries stop working and menstrual periods stop before age 40. Natural menopause usually occurs around age 50. A woman is said to be in menopause when she hasn't had a period for 12 months in a row. Symptoms of menopause include hot flashes, mood swings, night sweats, vaginal dryness, trouble concentrating, and infertility. Primary ovarian insufficiency can be caused by some cancer treatments, surgery to remove the ovaries, and certain diseases or genetic conditions. Also called early menopause, premature menopause, and premature ovarian failure.|NCI2016_02D:Absent or premature cessation of ovarian function due to a pathologic process originating within the ovaries.(NICHD)|MSH2017_2016_08_12:Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.|MEDLINEPLUS_20151021:Premature ovarian failure (POF) is when a woman's ovaries stop working before she is 40. POF is different from premature <a href='https://www.nlm.nih.gov/medlineplus/menopause.html'>menopause</a>. With premature menopause, your periods stop before age 40. You can no longer get pregnant. The cause can be natural or it can be a disease, surgery, chemotherapy, or radiation. With POF, some women still have occasional periods. They may even get pregnant. In most cases of POF, the cause is unknown. Missed periods are usually the first sign of POF. Later symptoms may be similar to those of natural menopause: <ul> <li>Hot flashes</li> <li>Night sweats</li> <li>Irritability</li> <li>Poor concentration</li> <li>Decreased sex drive</li> <li>Pain during sex</li> <li>Vaginal dryness</li> </ul> Doctors diagnose POF by doing a physical exam and lab and imaging tests. Most women with POF cannot get pregnant naturally. Fertility treatments help a few women; others use donor eggs to have children. There is no treatment that will restore normal ovarian function. However, many health care providers suggest taking hormones until age 50. NIH: National Institute of Child Health and Human Development|HPO2016_07_04:Malfunctioning of the ovaries such that a girl never begins menstruation. [HPO:probinson]
Version: v1
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Ovarian Failure, Premature

Role

preferred

Name

Premature Ovarian Failure 1

Role

preferred

Name

Premature Ovarian Failure 2A

Role

preferred

Name

Premature Ovarian Failure 2B

Role

preferred

Name

Premature Ovarian Failure 5

Role

preferred

Name

Premature Ovarian Failure 6

Role

preferred

Name

Premature Ovarian Failure 8

Role

preferred

Name

Premature Ovarian Failure 9

Role

preferred

Name

ADRENAL INSUFFICIENCY, NR5A1-RELATED

Role

preferred

Name

Gonadotropin-Resistant Ovary Syndrome

Role

preferred

Name

Hypergonadotropic Ovarian Failure, X-Linked

Role

preferred

Name

PREMATURE OVARIAN FAILURE 7 (disorder)

Role

preferred

Name

Premature Ovarian Failure 3 (Disorder)

Role

preferred

Name

POF

Role

alias

Name

POF1

Role

alias

Name

POF2A

Role

alias

Name

POF2B

Role

alias

Name

POF5

Role

alias

Name

POF6

Role

alias

Name

POF8

Role

alias

Name

POF9

Role

alias

Name

POFX

Role

alias

Name

PREMATURE OVARIAN FAILURE, X-LINKED

Role

alias

Name

Pof3

Role

alias

Name

Pof7

Role

alias

Name

Premature Ovarian Failure

Role

alias

Name

Premature Ovarian Failure 3

Role

alias

Name

Premature Ovarian Failure 7

Role

alias

Name

Primary Ovarian Failure

Role

alias

Name

Primary Ovarian Insufficiency

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Herb

HBDIS003259HBDIS003395HBDIS016179HBDIS016211HBDIS018725HBDIS019976HBDIS021480HBDIS022435HBDIS026722HBDIS027396HBDIS028796HBDIS029136HBDIS029517

Me Sh

D016649

Omim

300511300604311360608996611548612310612964615723615724

Umls

C0085215C1845105C1845293C1969060C2676742C3494522C3810367C3810376

Icd10

E28.3

Sym Map

SMDE01634SMDE01694SMDE03406SMDE04085SMDE04319SMDE04929SMDE05061SMDE11770

Do Class

DOID:7

Dis Ge Net

C0085215C0086367C1837008C1845105C1845293C1969060C2676742C2751825C3494522C3810367C3810376C4479664C4552079

Umls Sty

T047

Me Sh Class

C13C16C19

Tcmbank Disease

114131436115331770417751256562631278374681808

Itcmdb Generated

ITX-DISEASE-BFF6C090200F

Attributes

Merged source attributes and domain-specific metadata.

Version

v1v2

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Do Disease Class

disease of anatomical entity

Umls Disease Type

Disease or Syndrome

Disease Definition

NCI2016_NICHD_1602D:Absent or premature cessation of ovarian function due to an issue originating within the ovaries.|NCI2016_NCI-GLOSS_1602D:A condition in which the ovaries stop working and menstrual periods stop before age 40. Natural menopause usually occurs around age 50. A woman is said to be in menopause when she hasn't had a period for 12 months in a row. Symptoms of menopause include hot flashes, mood swings, night sweats, vaginal dryness, trouble concentrating, and infertility. Primary ovarian insufficiency can be caused by some cancer treatments, surgery to remove the ovaries, and certain diseases or genetic conditions. Also called early menopause, premature menopause, and premature ovarian failure.|NCI2016_02D:Absent or premature cessation of ovarian function due to a pathologic process originating within the ovaries.(NICHD)|MSH2017_2016_08_12:Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.|MEDLINEPLUS_20151021:Premature ovarian failure (POF) is when a woman's ovaries stop working before she is 40. POF is different from premature <a href='https://www.nlm.nih.gov/medlineplus/menopause.html'>menopause</a>. With premature menopause, your periods stop before age 40. You can no longer get pregnant. The cause can be natural or it can be a disease, surgery, chemotherapy, or radiation. With POF, some women still have occasional periods. They may even get pregnant. In most cases of POF, the cause is unknown. Missed periods are usually the first sign of POF. Later symptoms may be similar to those of natural menopause: <ul> <li>Hot flashes</li> <li>Night sweats</li> <li>Irritability</li> <li>Poor concentration</li> <li>Decreased sex drive</li> <li>Pain during sex</li> <li>Vaginal dryness</li> </ul> Doctors diagnose POF by doing a physical exam and lab and imaging tests. Most women with POF cannot get pregnant naturally. Fertility treatments help a few women; others use donor eggs to have children. There is no treatment that will restore normal ovarian function. However, many health care providers suggest taking hormones until age 50. NIH: National Institute of Child Health and Human Development|HPO2016_07_04:Malfunctioning of the ovaries such that a girl never begins menstruation. [HPO:probinson]

Me Sh Disease Class

Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Endocrine System DiseasesFemale Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Umls Semantic Type Name

Disease or Syndrome