DiseaseID 9318
副肿瘤性小脑变性
disease
NCI2016_02D:A rare, immune-mediated disorder characterized by cerebellar degeneration due to the presence of an often undetected malignancy (usually carcinoma or lymphoma) in an anatomic site other than the cerebellum. S
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Disease: 1Symptom: 2Target: 12Links: 14
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 9318
- Core Entity Id
- 66372
- Source Entity Count
- 1
- Preferred Name
- Paraneoplastic Cerebellar Degeneration
- Name Cn
- 副肿瘤性小脑变性
- Name Pinyin
- Fu Zhong Liu Xing Xiao Nao Bian Xing
- Name En
- Paraneoplastic Cerebellar Degeneration
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Nervous System Diseases; Neoplasms
- Do Class
- Hpo Class
- Mesh Class Name
- Neoplasms; Nervous System Diseases
- Hpo Class Name
- Do Class Name
- Disease Definition
- NCI2016_02D:A rare, immune-mediated disorder characterized by cerebellar degeneration due to the presence of an often undetected malignancy (usually carcinoma or lymphoma) in an anatomic site other than the cerebellum. Signs and symptoms include progressive ataxia, dysarthria, and nystagmus.|MSH2017_2016_08_12:Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
- Version
- v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Paraneoplastic Cerebellar Degeneration
Role
preferred
Name
Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated
Role
preferred
Cross References
Trusted external identifiers retained for this final record.
Herb
HBDIS008657HBDIS011513
Me Sh
D020362
Umls
C0393534
Sym Map
SMDE11929
Dis Ge Net
C0393534C0751913
Umls Sty
T047
Me Sh Class
C04C10
Tcmbank Disease
1159931747
Itcmdb Generated
ITX-DISEASE-13188541A364
Attributes
Merged source attributes and domain-specific metadata.
Version
v2
Suppress
0
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_02D:A rare, immune-mediated disorder characterized by cerebellar degeneration due to the presence of an often undetected malignancy (usually carcinoma or lymphoma) in an anatomic site other than the cerebellum. Signs and symptoms include progressive ataxia, dysarthria, and nystagmus.|MSH2017_2016_08_12:Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Me Sh Disease Class
Nervous System Diseases; Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms; Nervous System Diseases
Umls Semantic Type Name
Disease or Syndrome