DiseaseID 921
Miller Fisher综合征
disease
NCI2016_02D:An immunologic inflammatory disorder characterized by loss of myelin in the peripheral nerves. Patients present with progressive weakness and loss of sensory function in the legs and arms.|MSH2017_2016_08_12:
Relationship Network
Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.
Click a node to open it in a new tab
Disease: 1Formula: 7Herb: 5Symptom: 11Target: 22Links: 47
Arranging relationship network...
Record Fields
Scalar fields from the final disease record.
- Disease Id
- 921
- Core Entity Id
- 1040
- Source Entity Count
- 1
- Preferred Name
- Miller Fisher Syndrome
- Name Cn
- Miller Fisher综合征
- Name Pinyin
- Miller fisher Zong He Zheng
- Name En
- Miller Fisher Syndrome
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Eye Diseases; Immune System Diseases; Nervous System DiseasesImmune System Diseases; Nervous System Diseases
- Do Class
- disease of anatomical entity
- Hpo Class
- Mesh Class Name
- Eye Diseases; Immune System Diseases; Nervous System DiseasesImmune System Diseases; Nervous System Diseases
- Hpo Class Name
- Do Class Name
- disease of anatomical entity
- Disease Definition
- NCI2016_02D:An immunologic inflammatory disorder characterized by loss of myelin in the peripheral nerves. Patients present with progressive weakness and loss of sensory function in the legs and arms.|MSH2017_2016_08_12:A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Miller Fisher Syndrome
Role
preferred
Name
Guillain-Barre Syndrome
Role
preferred
Name
Guillain-Barre Syndrome, Familial
Role
preferred
Name
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Role
preferred
Name
Acute Infective Polyneuritis
Role
preferred
Name
Acute Inflammatory Demyelinating Polyneuropathy
Role
preferred
Name
AIDP
Role
alias
Name
Acute Autoimmune Neuropathy
Role
alias
Name
CIDP
Role
alias
Name
Chronic Inflammatory Demyelinating Polyneuritis
Role
alias
Name
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Role
alias
Name
GBS
Role
alias
Name
POLYNEUROPATHY, INFLAMMATORY DEMYELINATING, ACUTE
Role
alias
Name
POLYNEUROPATHY, INFLAMMATORY DEMYELINATING, CHRONIC
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Herb
HBDIS001228HBDIS008726HBDIS008731HBDIS021657HBDIS025538HBDIS027342
Me Sh
D019846D020275D020277
Omim
139393
Umls
C0018378C0393799C0393819C3542501C4083008
Icd10
G61.0G61.81
Sym Map
SMDE04641SMDE09174SMDE11028SMDE12301
Do Class
DOID:7
Dis Ge Net
C0018378C0393799C0393819C3542501C4083008C4551910
Umls Sty
T047
Me Sh Class
C10C11C20
Etcm Disease
Guillain-Barre Syndrome, Familial
Tcmbank Disease
118911343417927182372237053785949
Itcmdb Generated
ITX-DISEASE-6B165A55E539ITX-DISEASE-8D423B5483BCITX-DISEASE-A4FFCFD927DE
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v2
Suppress
0
Page Title
Disease Guillain-Barre Syndrome, Familial Details page
Do Class Name
disease of anatomical entity
Disease Type
disease
Do Disease Class
disease of anatomical entity
Umls Disease Type
Disease or Syndrome
Basic Information
Disease Name
Guillain-Barre Syndrome, Familial
Global Category
Genetic diseases;Rare diseases
Anatomical Category
Immune diseases;Neuronal diseases
Disease Definition
NCI2016_02D:An immunologic inflammatory disorder characterized by loss of myelin in the peripheral nerves. Patients present with progressive weakness and loss of sensory function in the legs and arms.|MSH2017_2016_08_12:A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)NCI2016_NICHD_1602D:A progressive autoimmune disorder of the peripheral nervous system characterized by respiratory insufficiency, limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.|NCI2016_02D:A rapidly progressive autoimmune disorder of the peripheral nervous system characterized by limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.|MSH2017_2016_08_12:An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)|MEDLINEPLUS_20151021:<p>Guillain-Barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (PNS). The PNS nerves connect your brain and spinal cord with the rest of your body. Damage to these nerves makes it hard for them to transmit signals. As a result, your muscles have trouble responding to your brain. No one knows what causes the syndrome. Sometimes it is triggered by an infection, surgery, or a vaccination. </p> <p>The first symptom is usually weakness or a tingling feeling in your legs. The feeling can spread to your upper body. In severe cases, you become almost paralyzed. This is life-threatening. You might need a respirator to breathe. Symptoms usually worsen over a period of weeks and then stabilize.</p> <p> Guillain-Barre can be hard to diagnose. Possible tests include nerve tests and a spinal tap. Most people recover. Recovery can take a few weeks to a few years. Treatment can help symptoms, and may include medicines or a procedure called plasma exchange.</p> <p >NIH: National Institute of Neurological Disorders and Stroke</p>|CSP2006:progressive ascending motor neuron paralysis of unknown etiology, frequently following an enteric or respiratory infection.NCI2016_NICHD_1602D:An autoimmune process characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia.|NCI2016_02D:An autoimmune process characterized by the clinical triad of ophthalmoplegia, ataxia, and areflexia.|MSH2017_2016_08_12:A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)SNOMEDCT_US_2016_09_01:An inflammatory neuropathy belonging to the clinical spectrum of Guillain-Barré syndrome. The clinical course is divided into three phases. The first phase (lasting a few weeks) has characteristics of rapidly progressive muscle weakness. It is symmetrical and may cause acute neuromuscular paralysis. Sensory disturbances, intense pains, and cramps may also occur. During the second phase (variable duration), symptoms become stable but other manifestations (cardiac arrhythmias, hyper/hypotension and gastric dysmotility) may occur. During the third (recovery) phase, lasting a few months or longer, symptoms slowly regress. Many patients have residual findings (weakness, sensory disturbances, fatigue or pain) for many months or even years. In the majority of cases, an infectious disease precedes the onset of limb weakness, with Campylobacter jejuni infection being the most frequent initiating event.|NCI2016_NICHD_1602D:A subtype of Guillain-Barre Syndrome that targets the myelin sheath, and is characterized by progressive weakness, distal paresthesia and autonomic dysfunction.|NCI2016_02D:An acute inflammatory process affecting the peripheral nervous system and nerve roots. It results in demyelination. It is often caused by an acute viral or bacterial infection.|NCI2016_02D:A subtype of Guillain-Barre syndrome that targets the myelin sheath, and is characterized by progressive weakness, distal paresthesia and autonomic dysfunction.
Me Sh Disease Class
Eye Diseases; Immune System Diseases; Nervous System DiseasesImmune System Diseases; Nervous System Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Eye Diseases; Immune System Diseases; Nervous System DiseasesImmune System Diseases; Nervous System Diseases
Umls Semantic Type Name
Disease or Syndrome