DiseaseID 916

进行性核上性麻痹

disease

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Disease: 1Symptom: 9Target: 12Links: 21

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Record Fields

Scalar fields from the final disease record.

Disease Id: 916
Core Entity Id: 1033
Source Entity Count: 1
Preferred Name: Progressive Supranuclear Palsy
Name Cn: 进行性核上性麻痹
Name Pinyin: Jin Xing Xing He Shang Xing Ma Bi
Name En: Progressive Supranuclear Palsy
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Eye Diseases; Nervous System Diseases; Pathological Conditions, Signs and Symptoms
Do Class: disease of anatomical entity
Hpo Class
Mesh Class Name: Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
Hpo Class Name
Do Class Name: disease of anatomical entity
Disease Definition: PSY2004:A progressive neurological disorder characterized by ophthalmoplegia, dystonia, memory impairment, personality disorders, and dementia. Etiology is unknown.|NCI2016_02D:A rare neurodegenerative disorder characterized by gait and balance difficulties and loss of coordination of eye movements.|MSH2017_2016_08_12:A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)|MEDLINEPLUS_20151021:Progressive supranuclear palsy (PSP) is a rare <a href='https://www.nlm.nih.gov/medlineplus/braindiseases.html'>brain disease</a>. It affects brain cells that control the movement of your eyes. This leads to serious and permanent problems with <a href='https://www.nlm.nih.gov/medlineplus/balanceproblems.html'>balance</a> and the way you walk. It usually occurs in middle-aged or elderly people. Symptoms are very different in each person, but may include personality changes, speech, vision and swallowing problems. Doctors sometimes confuse PSP with Parkinson's disease or Alzheimer's disease. PSP has no cure and no effective treatments. Walking aids, special glasses and certain medicines might help somewhat. Although the disease gets worse over time, it isn't fatal on its own. However, PSP is dangerous because it increases your risk of pneumonia and choking from swallowing problems and injuries from falling. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:spastic weakness of the muscles innervated by the cranial nerves, i.e., the muscle of the face, pharynx, and tongue, due to bilateral lesions of the corticospinal tract.
Version: v1,v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Progressive Supranuclear Palsy

Role

preferred

Name

Supranuclear Palsy, Progressive, 1

Role

preferred

Name

Ophthalmoplegia, Progressive Supranuclear

Role

preferred

Name

PSNP1

Role

alias

Name

PSP

Role

alias

Name

Palsy, Progressive Supranuclear

Role

alias

Name

Progressive Supranuclear Ophthalmoplegia [Steele-Richardson-Olszewski]

Role

alias

Name

STEELE-RICHARDSON-OLSZEWSKI SYNDROME

Role

alias

Name

Supranuclear Palsy, Progressive

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Herb

HBDIS002880HBDIS027328HBDIS027329

Me Sh

D013494

Omim

601104

Umls

C0038868

Icd10

G23.1

Sym Map

SMDE01568

Do Class

DOID:7

Dis Ge Net

C0038868C4551862C4551863

Umls Sty

T047

Me Sh Class

C10C11C23

Tcmbank Disease

14882817228399

Attributes

Merged source attributes and domain-specific metadata.

Version

v1,v2

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Do Disease Class

disease of anatomical entity

Umls Disease Type

Disease or Syndrome

Disease Definition

PSY2004:A progressive neurological disorder characterized by ophthalmoplegia, dystonia, memory impairment, personality disorders, and dementia. Etiology is unknown.|NCI2016_02D:A rare neurodegenerative disorder characterized by gait and balance difficulties and loss of coordination of eye movements.|MSH2017_2016_08_12:A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)|MEDLINEPLUS_20151021:Progressive supranuclear palsy (PSP) is a rare <a href='https://www.nlm.nih.gov/medlineplus/braindiseases.html'>brain disease</a>. It affects brain cells that control the movement of your eyes. This leads to serious and permanent problems with <a href='https://www.nlm.nih.gov/medlineplus/balanceproblems.html'>balance</a> and the way you walk. It usually occurs in middle-aged or elderly people. Symptoms are very different in each person, but may include personality changes, speech, vision and swallowing problems. Doctors sometimes confuse PSP with Parkinson's disease or Alzheimer's disease. PSP has no cure and no effective treatments. Walking aids, special glasses and certain medicines might help somewhat. Although the disease gets worse over time, it isn't fatal on its own. However, PSP is dangerous because it increases your risk of pneumonia and choking from swallowing problems and injuries from falling. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:spastic weakness of the muscles innervated by the cranial nerves, i.e., the muscle of the face, pharynx, and tongue, due to bilateral lesions of the corticospinal tract.

Me Sh Disease Class

Eye Diseases; Nervous System Diseases; Pathological Conditions, Signs and Symptoms

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases

Umls Semantic Type Name

Disease or Syndrome