DiseaseID 8886

Pearson骨髓-胰腺综合征

disease

NCI2016_02D:A rare syndrome with poor prognosis caused by single, large deletions of mitochondrial DNA. It usually presents in infancy with bone marrow failure, anemia, neutropenia, thrombocytopenia, vacuolation of the h

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Disease: 1Symptom: 6Target: 12Links: 18
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Record Fields

Scalar fields from the final disease record.

Disease Id
8886
Core Entity Id
65881
Source Entity Count
1
Preferred Name
Pearson'S Marrow-Pancreas Syndrome
Name Cn
Pearson骨髓-胰腺综合征
Name Pinyin
Pearson Gu Sui - Yi Xian Zong He Zheng
Name En
Pearson'S Marrow-Pancreas Syndrome
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Pathological Conditions, Signs and SymptomsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases; Musculoskeletal Diseases
Do Class
genetic disease; disease of metabolism
Hpo Class
Mesh Class Name
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Hpo Class Name
Do Class Name
disease of metabolism; genetic disease
Disease Definition
NCI2016_02D:A rare syndrome with poor prognosis caused by single, large deletions of mitochondrial DNA. It usually presents in infancy with bone marrow failure, anemia, neutropenia, thrombocytopenia, vacuolation of the hematopoietic precursor cells, lactic acidosis, and fibrosis and acinar atrophy of the pancreas that results in malabsorption and chronic diarrhea. Approximately half of the patients die in infancy or early childhood.
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Pearson'S Marrow-Pancreas Syndrome
Role
preferred
Name
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Role
preferred
Name
Acyl-Coa Dehydrogenase Very Long Chain Deficiency
Role
alias
Name
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of
Role
alias
Name
Pearson Marrow-Pancreas Syndrome
Role
alias
Name
Pearson Syndrome
Role
alias
Name
Vlcad Deficiency
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Herb
HBDIS008074HBDIS022711
Omim
201475557000
Umls
C0342784
Sym Map
SMDE12006
Do Class
DOID:0014667DOID:630
Dis Ge Net
C0342784C3887523
Umls Sty
T047
Me Sh Class
C05C10C15C16C18C23
Tcmbank Disease
60586430

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of metabolism; genetic disease
Disease Type
disease
Do Disease Class
genetic disease; disease of metabolism
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_02D:A rare syndrome with poor prognosis caused by single, large deletions of mitochondrial DNA. It usually presents in infancy with bone marrow failure, anemia, neutropenia, thrombocytopenia, vacuolation of the hematopoietic precursor cells, lactic acidosis, and fibrosis and acinar atrophy of the pancreas that results in malabsorption and chronic diarrhea. Approximately half of the patients die in infancy or early childhood.
Me Sh Disease Class
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases; Pathological Conditions, Signs and SymptomsCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases; Musculoskeletal Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases; Hemic and Lymphatic DiseasesPathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Disease or Syndrome