DiseaseID 6981

闭塞性细支气管炎伴机化性肺炎

disease

NCI2016_02D:A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dy

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Disease: 1Symptom: 2Target: 10Links: 12
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Record Fields

Scalar fields from the final disease record.

Disease Id
6981
Core Entity Id
63709
Source Entity Count
2
Preferred Name
Bronchiolitis Obliterans Organizing Pneumonia
Name Cn
闭塞性细支气管炎伴机化性肺炎
Name Pinyin
Bi Se Xing Xi Zhi Qi Guan Yan Ban Ji Hua Xing Fei Yan
Name En
Bronchiolitis Obliterans Organizing Pneumonia
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Respiratory Tract Diseases
Do Class
disease of anatomical entity
Hpo Class
Abnormality of the respiratory system
Mesh Class Name
Respiratory Tract Diseases
Hpo Class Name
Abnormality of the respiratory system
Do Class Name
disease of anatomical entity
Disease Definition
NCI2016_02D:A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.(MeSH)|MSH2017_2016_08_12:An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.|HPO2016_07_04:Bronchiolitis obliterans organizing pneumonia (BOOP) is and interstitial lung abnormalitiy characterized histopathologically by plugs of granulation tissue lying within small airways, alveolar ducts, and alveoli and by chronic inflammatory cell infiltration in alveolar walls. Patients with BOOP generally present with subacute illness, including shortness of breath, fever, malaise, and weight loss. [DDD:tkuijpers, HPO:probinson, pmid:20858818]
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Bronchiolitis Obliterans Organizing Pneumonia
Role
preferred
Name
Boop
Role
alias
Name
Cryptogenic Organizing Pneumonia
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0011945
Herb
HBDIS005455
Me Sh
D018549
Umls
C0242770
Icd10
J84.116
Sym Map
SMDE06637
Do Class
DOID:7
Dis Ge Net
C0242770
Umls Sty
T047
Hpo Class
HP:0002086
Me Sh Class
C08
Tcmbank Disease
22806380
Itcmdb Generated
ITX-DISEASE-99C6ACD0AB2C

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity
Disease Type
disease
Hpo Class Name
Abnormality of the respiratory system
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of the respiratory system
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_02D:A disease formerly considered a form of interstitial pneumonia. Its etiology is obscure but it may be associated with toxic fumes, infection, and connective tissue disease. Clinical symptoms include cough, dyspnea and influenza-like symptoms with the development of the usual interstitial pneumonia in many cases. Obstructive symptoms are limited to smokers. There are patchy polypoid masses of intra-alveolar granulation tissue in small airway lumina and alveolar ducts. "Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.(MeSH)|MSH2017_2016_08_12:An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a "pneumonia-like" illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.|HPO2016_07_04:Bronchiolitis obliterans organizing pneumonia (BOOP) is and interstitial lung abnormalitiy characterized histopathologically by plugs of granulation tissue lying within small airways, alveolar ducts, and alveoli and by chronic inflammatory cell infiltration in alveolar walls. Patients with BOOP generally present with subacute illness, including shortness of breath, fever, malaise, and weight loss. [DDD:tkuijpers, HPO:probinson, pmid:20858818]
Me Sh Disease Class
Respiratory Tract Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Respiratory Tract Diseases
Umls Semantic Type Name
Disease or Syndrome