DiseaseID 6253
神经内分泌肿瘤
disease
NCI2016_CDISC_1602D:A malignant neuroendocrine neoplasm comprising cells containing secretory granules.|NCI2016_02D:A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive
Relationship Network
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Disease: 1Symptom: 6Target: 12Links: 18
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 6253
- Core Entity Id
- 62877
- Source Entity Count
- 2
- Preferred Name
- Neuroendocrine Tumors
- Name Cn
- 神经内分泌肿瘤
- Name Pinyin
- Shen Jing Nei Fen Mi Zhong Liu
- Name En
- Neuroendocrine Tumors
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Neoplastic Process
- Disgenet Type
- disease
- Mesh Class
- Neoplasms
- Do Class
- disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferation
- Hpo Class
- Neoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
- Mesh Class Name
- Neoplasms
- Hpo Class Name
- Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
- Do Class Name
- disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferation
- Disease Definition
- NCI2016_CDISC_1602D:A malignant neuroendocrine neoplasm comprising cells containing secretory granules.|NCI2016_02D:A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma.|MSH2017_2016_08_12:A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)
- Version
- v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Neuroendocrine Tumors
Role
preferred
Name
Carcinoma, Neuroendocrine
Role
preferred
Name
Neuroendocrine Carcinoma
Role
alias
Name
Neuroendocrine Neoplasia
Role
alias
Name
Neuroendocrine Neoplasm
Role
alias
Name
Neuroendocrine Tumor
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0100634
Herb
HBDIS004426HBDIS004470
Me Sh
D018278D018358
Umls
C0206695C0206754
Icd10
D3A.8
Sym Map
SMDE06747SMDE11436
Do Class
DOID:14566DOID:7
Dis Ge Net
C0206695C0206754
Umls Sty
T191
Hpo Class
HP:0000707HP:0000818HP:0002664
Me Sh Class
C04
Tcmbank Disease
29033038932158
Itcmdb Generated
ITX-DISEASE-CA24DA4B5891
Attributes
Merged source attributes and domain-specific metadata.
Version
v2
Suppress
0
Do Class Name
disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferation
Disease Type
diseasegroup
Hpo Class Name
Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
Do Disease Class
disease of anatomical entity; disease of cellular proliferationdisease of cellular proliferation
Hpo Disease Class
Neoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
Umls Disease Type
Neoplastic Process
Disease Definition
NCI2016_CDISC_1602D:A malignant neuroendocrine neoplasm comprising cells containing secretory granules.|NCI2016_02D:A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma.|MSH2017_2016_08_12:A group of carcinomas which share a characteristic morphology, often being composed of clusters and trabecular sheets of round "blue cells", granular chromatin, and an attenuated rim of poorly demarcated cytoplasm. Neuroendocrine tumors include carcinoids, small ("oat") cell carcinomas, medullary carcinoma of the thyroid, Merkel cell tumor, cutaneous neuroendocrine carcinoma, pancreatic islet cell tumors, and pheochromocytoma. Neurosecretory granules are found within the tumor cells. (Segen, Dictionary of Modern Medicine, 1992)NCI2016_NCI-GLOSS_1602D:A tumor that forms from cells that release hormones in response to a signal from the nervous system. Some examples of neuroendocrine tumors are carcinoid tumors, islet cell tumors, medullary thyroid carcinomas, pheochromocytomas, and neuroendocrine carcinomas of the skin (Merkel cell cancer). These tumors may secrete higher-than-normal amounts of hormones, which can cause many different symptoms.|NCI2016_02D:A benign or malignant neoplasm composed of cells of neuroendocrine origin. Representative examples include paraganglioma, carcinoid tumor, and neuroendocrine carcinoma.|MSH2017_2016_08_12:Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
Me Sh Disease Class
Neoplasms
Dis Ge Net Disease Type
diseasegroup
Disease Class Name Me Sh
Neoplasms
Umls Semantic Type Name
Neoplastic Process