DiseaseID 6191

Ki-1阳性间变性大细胞淋巴瘤

disease

NCI2016_NCI-GLOSS_1602D:An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface, and may appear in the lymph node

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Disease: 1Symptom: 1Target: 12Links: 13
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Record Fields

Scalar fields from the final disease record.

Disease Id
6191
Core Entity Id
62809
Source Entity Count
2
Preferred Name
Ki-1+ Anaplastic Large Cell Lymphoma
Name Cn
Ki-1阳性间变性大细胞淋巴瘤
Name Pinyin
Ki-1 Yang Xing Jian Bian Xing Da Xi Bao Lin Ba Liu
Name En
Ki-1+ Anaplastic Large Cell Lymphoma
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Neoplastic Process
Disgenet Type
disease
Mesh Class
Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases
Do Class
Hpo Class
Abnormality of blood and blood-forming tissues; Neoplasm
Mesh Class Name
Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Hpo Class Name
Neoplasm; Abnormality of blood and blood-forming tissues
Do Class Name
Disease Definition
NCI2016_NCI-GLOSS_1602D:An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver.|NCI2016_02D:A peripheral (mature) T-cell lymphoma, consisting of usually large anaplastic, CD30 positive cells. The majority of cases are positive for the anaplastic large cell lymphoma (ALK) protein. The most frequently seen genetic alteration is a t(2;5) translocation. Majority of patients present with advanced disease. The most important prognostic indicator is ALK positivity, which has been associated with a favorable prognosis. (WHO, 2001)|MSH2017_2016_08_12:A systemic, large-cell, non-Hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the CD30 ANTIGEN. These so-called "hallmark" cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and MALIGNANT HISTIOCYTOSIS.|HPO2016_07_04:A type of T-cell lymphoma that is characterized by so-called hallmark cells with a pleomorphic appearance that express the CD30 antigen, are lobulated, and have indented nuclei. These so-called hallmark cells have lobulated and indented nuclei. [HPO:probinson]
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Ki-1+ Anaplastic Large Cell Lymphoma
Role
preferred
Name
Anaplastic Large-Cell Lymphoma
Role
alias
Name
Cd30+ Anaplastic Large-Cell Lymphoma
Role
alias
Name
Lymphoma, Large-Cell, Anaplastic
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0012193
Herb
HBDIS004348
Me Sh
D017728
Umls
C0206180
Icd10
C84.6
Sym Map
SMDE10208
Dis Ge Net
C0206180
Umls Sty
T191
Hpo Class
HP:0001871HP:0002664
Me Sh Class
C04C15C20
Tcmbank Disease
153881760
Itcmdb Generated
ITX-DISEASE-2433A538AB8E

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Disease Type
disease
Hpo Class Name
Neoplasm; Abnormality of blood and blood-forming tissues
Hpo Disease Class
Abnormality of blood and blood-forming tissues; Neoplasm
Umls Disease Type
Neoplastic Process
Disease Definition
NCI2016_NCI-GLOSS_1602D:An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30 or Ki-1 on the surface, and may appear in the lymph nodes, skin, bones, soft tissues, lungs, or liver.|NCI2016_02D:A peripheral (mature) T-cell lymphoma, consisting of usually large anaplastic, CD30 positive cells. The majority of cases are positive for the anaplastic large cell lymphoma (ALK) protein. The most frequently seen genetic alteration is a t(2;5) translocation. Majority of patients present with advanced disease. The most important prognostic indicator is ALK positivity, which has been associated with a favorable prognosis. (WHO, 2001)|MSH2017_2016_08_12:A systemic, large-cell, non-Hodgkin, malignant lymphoma characterized by cells with pleomorphic appearance and expressing the CD30 ANTIGEN. These so-called "hallmark" cells have lobulated and indented nuclei. This lymphoma is often mistaken for metastatic carcinoma and MALIGNANT HISTIOCYTOSIS.|HPO2016_07_04:A type of T-cell lymphoma that is characterized by so-called hallmark cells with a pleomorphic appearance that express the CD30 antigen, are lobulated, and have indented nuclei. These so-called hallmark cells have lobulated and indented nuclei. [HPO:probinson]
Me Sh Disease Class
Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Neoplastic Process