DiseaseID 5616

干燥综合征

disease

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Disease: 1Experiment: 2Symptom: 12Target: 12Links: 26

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Record Fields

Scalar fields from the final disease record.

Disease Id: 5616
Core Entity Id: 62149
Source Entity Count: 1
Preferred Name: Sicca Syndrome
Name Cn: 干燥综合征
Name Pinyin: Gan Zao Zong He Zheng
Name En: Sicca Syndrome
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Stomatognathic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Immune System Diseases; Musculoskeletal Diseases
Do Class: disease of anatomical entity
Hpo Class
Mesh Class Name: Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
Hpo Class Name
Do Class Name: disease of anatomical entity
Disease Definition: NCI2016_NICHD_1602D:Autoimmune epithelial inflammation often affecting the salivary and lacrimal glands (causing dry mouth and dry eyes) with potential extraglandular manifestations. In children, it most commonly presents with recurrent parotitis. It may occur alone (primary) or in association with another autoimmune disease (secondary).|NCI2016_NCI-GLOSS_1602D:An autoimmune disease that affects the tear glands and salivary glands, and may affect glands in the stomach, pancreas, and intestines. The disease causes dry eyes and mouth, and may cause dryness in the nose, throat, air passages, skin, and vagina. It may also cause inflammation in the joints, muscles, and skin; pneumonia; tingling in the fingers and toes; and fatigue. It often occurs with rheumatoid arthritis or other connective tissue diseases.|NCI2016_02D:An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus.|MSH2017_2016_08_12:Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.|MEDLINEPLUS_20151021:Sjogren's syndrome is a disease that causes dryness in your mouth and eyes. It can also lead to dryness in other places that need moisture, such as your nose, throat and skin. Most people who get Sjogren's syndrome are older than 40. Nine of 10 are women. Sjogren's syndrome is sometimes linked to rheumatic problems such as <a href='https://www.nlm.nih.gov/medlineplus/rheumatoidarthritis.html'>rheumatoid arthritis</a>. Sjogren's syndrome is an <a href='https://www.nlm.nih.gov/medlineplus/autoimmunediseases.html'>autoimmune disease</a>. If you have an autoimmune disease, your immune system, which is supposed to fight disease, mistakenly attacks parts of your own body. In Sjogren's syndrome, your immune system attacks the glands that make tears and saliva. It may also affect your joints, lungs, kidneys, blood vessels, digestive organs and nerves. The main symptoms are: <ul> <li> Dry eyes</li> <li> <a href='https://www.nlm.nih.gov/medlineplus/drymouth.html'>Dry mouth</a></li> </ul> Treatment focuses on relieving symptoms. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases|CSP2006:symptom complex of unknown etiology, usually occurring in middle-aged or older women, marked by the triad of keratoconjunctivitis sicca with or without lacrimal gland enlargement, xerostomia with or without salivary gland enlargement, and the presence of a connective tissue disease, usually rheumatoid arthritis but sometimes systemic lupus erythematosus, scleroderma, or polymyositis; an abnormal immune response has been implicated.|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Sicca Syndrome

Role

preferred

Name

Sjogren'S Syndrome

Role

preferred

Name

Sicca Syndrome [Sjogren]

Role

alias

Name

Sjogren Syndrome

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Herb

HBDIS003439HBDIS014451

Sym Map

SMDE13183

Do Class

DOID:7

Dis Ge Net

C0086981C1527336

Umls Sty

T047

Me Sh Class

C05C07C11C17C20

Tcmbank Disease

165651801625500

Itcmdb Generated

ITX-DISEASE-2CDE1166351C

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Do Disease Class

disease of anatomical entity

Umls Disease Type

Disease or Syndrome

Disease Definition

NCI2016_NICHD_1602D:Autoimmune epithelial inflammation often affecting the salivary and lacrimal glands (causing dry mouth and dry eyes) with potential extraglandular manifestations. In children, it most commonly presents with recurrent parotitis. It may occur alone (primary) or in association with another autoimmune disease (secondary).|NCI2016_NCI-GLOSS_1602D:An autoimmune disease that affects the tear glands and salivary glands, and may affect glands in the stomach, pancreas, and intestines. The disease causes dry eyes and mouth, and may cause dryness in the nose, throat, air passages, skin, and vagina. It may also cause inflammation in the joints, muscles, and skin; pneumonia; tingling in the fingers and toes; and fatigue. It often occurs with rheumatoid arthritis or other connective tissue diseases.|NCI2016_02D:An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus.|MSH2017_2016_08_12:Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.|MEDLINEPLUS_20151021:Sjogren's syndrome is a disease that causes dryness in your mouth and eyes. It can also lead to dryness in other places that need moisture, such as your nose, throat and skin. Most people who get Sjogren's syndrome are older than 40. Nine of 10 are women. Sjogren's syndrome is sometimes linked to rheumatic problems such as <a href='https://www.nlm.nih.gov/medlineplus/rheumatoidarthritis.html'>rheumatoid arthritis</a>. Sjogren's syndrome is an <a href='https://www.nlm.nih.gov/medlineplus/autoimmunediseases.html'>autoimmune disease</a>. If you have an autoimmune disease, your immune system, which is supposed to fight disease, mistakenly attacks parts of your own body. In Sjogren's syndrome, your immune system attacks the glands that make tears and saliva. It may also affect your joints, lungs, kidneys, blood vessels, digestive organs and nerves. The main symptoms are: <ul> <li> Dry eyes</li> <li> <a href='https://www.nlm.nih.gov/medlineplus/drymouth.html'>Dry mouth</a></li> </ul> Treatment focuses on relieving symptoms. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases|CSP2006:symptom complex of unknown etiology, usually occurring in middle-aged or older women, marked by the triad of keratoconjunctivitis sicca with or without lacrimal gland enlargement, xerostomia with or without salivary gland enlargement, and the presence of a connective tissue disease, usually rheumatoid arthritis but sometimes systemic lupus erythematosus, scleroderma, or polymyositis; an abnormal immune response has been implicated.|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood|CHV2011_02:A chronic inflammation of the tear and salivary glands, often accompanied by rheumatoid arthritis and the presence of autoantibodies in the blood

Me Sh Disease Class

Stomatognathic Diseases; Eye Diseases; Skin and Connective Tissue Diseases; Immune System Diseases; Musculoskeletal Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases

Umls Semantic Type Name

Disease or Syndrome