DiseaseID 5165

夏伊-德雷格综合征

disease

NCI2016_02D:A rare neurodegenerative disorder characterized by loss of autonomic nervous system functions and disturbances of motor, balance and muscle coordination.|MSH2017_2016_08_12:A syndrome complex composed of thre

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Disease: 1Symptom: 9Target: 12Links: 21
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Record Fields

Scalar fields from the final disease record.

Disease Id
5165
Core Entity Id
61622
Source Entity Count
1
Preferred Name
Shy-Drager Syndrome
Name Cn
夏伊-德雷格综合征
Name Pinyin
Xia Yi - De Lei Ge Zong He Zheng
Name En
Shy-Drager Syndrome
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Cardiovascular Diseases; Nervous System DiseasesNervous System Diseases
Do Class
disease of anatomical entity
Hpo Class
Mesh Class Name
Nervous System DiseasesNervous System Diseases; Cardiovascular Diseases
Hpo Class Name
Do Class Name
disease of anatomical entity
Disease Definition
NCI2016_02D:A rare neurodegenerative disorder characterized by loss of autonomic nervous system functions and disturbances of motor, balance and muscle coordination.|MSH2017_2016_08_12:A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Shy-Drager Syndrome
Role
preferred
Name
Multiple System Atrophy
Role
preferred

Cross References

Trusted external identifiers retained for this final record.

Herb
HBDIS002746HBDIS008671
Me Sh
D012791D019578
Umls
C0037019C0393571
Sym Map
SMDE11158SMDE13133
Do Class
DOID:7
Dis Ge Net
C0037019C0393571
Umls Sty
T046T047
Me Sh Class
C10C14
Tcmbank Disease
2136828001

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity
Disease Type
diseasephenotype
Do Disease Class
disease of anatomical entity
Umls Disease Type
Disease or SyndromePathologic Function
Disease Definition
NCI2016_02D:A rare neurodegenerative disorder characterized by loss of autonomic nervous system functions and disturbances of motor, balance and muscle coordination.|MSH2017_2016_08_12:A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)NCI2016_02D:A rare, progressive neurodegenerative disorder affecting the autonomic functions. It is manifested with masked facial appearance or reduced ability to show facial expression, staring, chewing difficulties, impotence, sleep abnormalities, myalgias, muscle rigidity, movement abnormalities, tremors, voice and speech changes, depression, and dementia.|MSH2017_2016_08_12:A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536)
Me Sh Disease Class
Cardiovascular Diseases; Nervous System DiseasesNervous System Diseases
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Nervous System DiseasesNervous System Diseases; Cardiovascular Diseases
Umls Semantic Type Name
Disease or SyndromePathologic Function