DiseaseID 5038

雷诺病

disease

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Disease: 1Symptom: 7Target: 12Links: 19

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Record Fields

Scalar fields from the final disease record.

Disease Id: 5038
Core Entity Id: 61478
Source Entity Count: 1
Preferred Name: Raynaud Disease
Name Cn: 雷诺病
Name Pinyin: Lei Nuo Bing
Name En: Raynaud Disease
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Cardiovascular Diseases
Do Class: disease of anatomical entity
Hpo Class: Abnormality of the cardiovascular system
Mesh Class Name: Cardiovascular Diseases
Hpo Class Name: Abnormality of the cardiovascular system
Do Class Name: disease of anatomical entity
Disease Definition: MSH2017_2016_08_12:An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.|MEDLINEPLUS_20151021:Raynaud's disease is a rare disorder of the blood vessels, usually in the fingers and toes. It causes the blood vessels to narrow when you are cold or feeling stressed. When this happens, blood can't get to the surface of the skin and the affected areas turn white and blue. When the blood flow returns, the skin turns red and throbs or tingles. In severe cases, loss of blood flow can cause sores or tissue death. Primary Raynaud's happens on its own. The cause is not known. There is also secondary Raynaud's, which is caused by injuries, other diseases, or certain medicines. People in colder climates are more likely to develop Raynaud's. It is also more common in women, people with a family history, and those over age 30. Treatment for Raynaud's may include drugs to keep the blood vessels open. There are also simple things you can do yourself, such as <ul> <li>Soaking hands in warm water at the first sign of an attack</li> <li> Keeping your hands and feet warm in cold weather</li> <li>Avoiding triggers, such as certain medicines and stress</li> </ul> NIH: National Heart, Lung, and Blood Institute|CSP2006:intermittent attacks of ischemia in the fingers, toes, ears, or nose, accompanied by pain, pallor, and prickling; phenomenon applies to secondary symptoms, disease when cause is unknown.|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulation|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulation|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulation
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Raynaud Disease

Role

preferred

Name

Raynaud Phenomenon

Role

preferred

Name

Secondary Raynaud'S Phenomenon

Role

preferred

Name

Raynaud'S Phenomenon

Role

alias

Name

Raynaud'S Syndrome

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Hpo

HP:0030880

Herb

HBDIS002569HBDIS002570HBDIS013191

Me Sh

D011928

Omim

179600

Umls

C0034734C0034735

Icd10

I73.0

Sym Map

SMDE12683SMDE12684

Do Class

DOID:7

Dis Ge Net

C0034734C0034735C1282916

Umls Sty

T047

Hpo Class

HP:0001626

Me Sh Class

C14

Tcmbank Disease

174572785845425445

Itcmdb Generated

ITX-DISEASE-089747FCD032ITX-DISEASE-734F43EABBC5

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Hpo Class Name

Abnormality of the cardiovascular system

Do Disease Class

disease of anatomical entity

Hpo Disease Class

Abnormality of the cardiovascular system

Umls Disease Type

Disease or Syndrome

Disease Definition

MSH2017_2016_08_12:An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.|MEDLINEPLUS_20151021:Raynaud's disease is a rare disorder of the blood vessels, usually in the fingers and toes. It causes the blood vessels to narrow when you are cold or feeling stressed. When this happens, blood can't get to the surface of the skin and the affected areas turn white and blue. When the blood flow returns, the skin turns red and throbs or tingles. In severe cases, loss of blood flow can cause sores or tissue death. Primary Raynaud's happens on its own. The cause is not known. There is also secondary Raynaud's, which is caused by injuries, other diseases, or certain medicines. People in colder climates are more likely to develop Raynaud's. It is also more common in women, people with a family history, and those over age 30. Treatment for Raynaud's may include drugs to keep the blood vessels open. There are also simple things you can do yourself, such as <ul> <li>Soaking hands in warm water at the first sign of an attack</li> <li> Keeping your hands and feet warm in cold weather</li> <li>Avoiding triggers, such as certain medicines and stress</li> </ul> NIH: National Heart, Lung, and Blood Institute|CSP2006:intermittent attacks of ischemia in the fingers, toes, ears, or nose, accompanied by pain, pallor, and prickling; phenomenon applies to secondary symptoms, disease when cause is unknown.|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulation|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulation|CHV2011_02:blood vessel disease that causes exaggerated responses to cold and stress with poor blood circulationNCI2016_NICHD_1602D:An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease.|NCI2016_FDA_1602D:Intermittent bilateral attacks of ischemia of the fingers or toes and sometimes of the ears or nose, marked by severe pallor, and often accompanied by paresthesia and pain.|NCI2016_02D:An episodic vasoconstriction resulting in discoloration of the skin and pain in the affected areas, often involving fingers or toes. Classically associated with triphasic color changes (white, blue, red) but may be biphasic. Often occurs in response to cold temperatures or emotional stress. May be primary or secondary to an underlying autoimmune disease.|AIR93:WHAT: Raynaud's phenomenon. Raynaud's Phenomenon: the paroxysmal constriction of the small arteries and arterioles of the hands or feet, usually precipitated by cold or emotional upset, resulting in pallor and cyanosis of the fingers or toes following a characteristic pattern. WHY: Raynaud's phenomenon may occur in mixed connective tissue disease, systemic lupus erythematosus, progressive systemic sclerosis, poly- myositis/dermatomyositis, and rheumatoid arthritis associated with Sjogren's syndrome. HOW: In Raynaud's phenomenon there are three classic color changes of the fingers or toes. First, vasoconstriction results in a white blanching of the fingertips. Second, vasodilatation with sludging of vascular flow follows and results in blue, cyanotic digits. Finally, with recovery, there is increased blood flow with resulting erythema of the fingers. With observation of two of the three color changes, Raynaud's phenomenon is considered present. Local body cooling (by placing the hands in ice cold water) may demonstrate Raynaud's phenomenon, but some cases require general body cooling before the characteristic color phases occur. Permanent tissue damage can be induced by this testing, which therefore must be done only when absolutely necessary. If the digits show persistent cyanosis or there is evidence of pre-existing necrosis, performing this test is especially hazardous. One or more digits may be involved in Raynaud's phenomenon, and this involvement may be unilateral. REFS: 1) Spittell, JA: "Raynaud's phenomenon and allied vasospastic disorders". In Juergens, JL et al. (eds.): Peripheral Vascular Diseases, pp. 555-83. Philadelphia: W.B. Saunders Co., 1980. 2) Porter, JM; Snider, RL; Bardana, EJ; Rosch, J and Eidemiller, LR: The diagnosis and treatment of Raynaud's phenomenon. Surgery 77:11, 1975. DN19300-3.

Me Sh Disease Class

Cardiovascular Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Cardiovascular Diseases

Umls Semantic Type Name

Disease or Syndrome