DiseaseID 4902
嗜铬细胞瘤
disease
NCI2016_NCI-GLOSS_1602D:Tumor that forms in the center of the adrenal gland (gland located above the kidney) that causes it to make too much adrenaline. Pheochromocytomas are usually benign (not cancer) but can cause hig
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Disease: 1Symptom: 5Target: 12Links: 17
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 4902
- Core Entity Id
- 61322
- Source Entity Count
- 1
- Preferred Name
- Pheochromocytoma
- Name Cn
- 嗜铬细胞瘤
- Name Pinyin
- Shi Ge Xi Bao Liu
- Name En
- Pheochromocytoma
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Finding
- Disgenet Type
- disease
- Mesh Class
- Neoplasms
- Do Class
- disease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Neoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
- Mesh Class Name
- Neoplasms
- Hpo Class Name
- Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
- Do Class Name
- disease of anatomical entity; disease of cellular proliferation
- Disease Definition
- NCI2016_NCI-GLOSS_1602D:Tumor that forms in the center of the adrenal gland (gland located above the kidney) that causes it to make too much adrenaline. Pheochromocytomas are usually benign (not cancer) but can cause high blood pressure, pounding headaches, heart palpitations, flushing of the face, nausea, and vomiting.|NCI2016_CDISC_1602D:A neoplasm of the adrenal gland medulla, for which the malignancy status has not been established.|NCI2016_02D:A benign or malignant neuroendocrine neoplasm of the sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the adrenal medulla. Clinical presentation includes headaches, palpitations, chest and abdominal pain, hypertension, fever, and tremor. Microscopically, a characteristic nesting (zellballen) growth pattern is usually seen. Other growth patterns including trabecular pattern may also be present.|MSH2017_2016_08_12:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)|MEDLINEPLUS_20151021:<p>Pheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. Although they are usually <a href='https://www.nlm.nih.gov/medlineplus/benigntumors.html'>benign</a>, pheochromocytomas often cause the adrenal gland to make too many hormones. This can lead to high blood pressure and cause symptoms such as </p> <ul> <li>Headaches</li> <li>Sweating</li> <li>Pounding of the heart</li> <li>Being shaky</li> <li>Being extremely pale</li> </ul> <p>Sometimes pheochromocytoma is part of another condition called multiple endocrine neoplasia syndrome (MEN). People with MEN often have other cancers and other problems involving hormones. </p> <p>Doctors use lab tests and imaging tests to diagnose it. Surgery is the most common treatment. Other options include radiation therapy, chemotherapy, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells.</p> <p >NIH: National Cancer Institute</p>|HPO2016_07_04:Pheochromocytomas (also known as chromaffin tumors) produce, store, and secrete catecholamines. Pheochromocytomas usually originate from the adrenal medulla but may also develop from chromaffin cells in or about sympathetic ganglia. A common symptom of pheochromocytoma is hypertension owing to release of catecholamines. [HPO:probinson]|HPO2016_07_04:Pheochromocytoma originating from the adrenal medulla. [HPO:curators]|CSP2006:usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia; the cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent.|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA
- Version
- v1,v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Pheochromocytoma
Role
preferred
Name
Pheochromocytoma, Susceptibility To
Role
preferred
Name
Pheochromocytoma, Extra-Adrenal
Role
preferred
Name
Chromaffin Tumors
Role
alias
Name
Extraadrenal Pheochromocytoma
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0002666HP:0006737
Herb
HBDIS002381HBDIS012815HBDIS020609
Me Sh
D010673
Omim
171300
Umls
C0031511C3149711
Sym Map
SMDE00871SMDE12140
Do Class
DOID:14566DOID:7
Dis Ge Net
C0031511C1257877C3149711
Umls Sty
T033T191
Hpo Class
HP:0000707HP:0000818HP:0002664
Me Sh Class
C04
Tcmbank Disease
11244136232063330890
Itcmdb Generated
ITX-DISEASE-59FF8CC2A422ITX-DISEASE-9B77549AB032
Attributes
Merged source attributes and domain-specific metadata.
Version
v1,v2v2
Suppress
0
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of the endocrine system; Abnormality of the nervous system; Neoplasm
Do Disease Class
disease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Neoplasm; Abnormality of the nervous system; Abnormality of the endocrine system
Umls Disease Type
FindingNeoplastic Process
Disease Definition
NCI2016_NCI-GLOSS_1602D:Tumor that forms in the center of the adrenal gland (gland located above the kidney) that causes it to make too much adrenaline. Pheochromocytomas are usually benign (not cancer) but can cause high blood pressure, pounding headaches, heart palpitations, flushing of the face, nausea, and vomiting.|NCI2016_CDISC_1602D:A neoplasm of the adrenal gland medulla, for which the malignancy status has not been established.|NCI2016_02D:A benign or malignant neuroendocrine neoplasm of the sympathetic nervous system that secretes catecholamines. It arises from the chromaffin cells of the adrenal medulla. Clinical presentation includes headaches, palpitations, chest and abdominal pain, hypertension, fever, and tremor. Microscopically, a characteristic nesting (zellballen) growth pattern is usually seen. Other growth patterns including trabecular pattern may also be present.|MSH2017_2016_08_12:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)|MEDLINEPLUS_20151021:<p>Pheochromocytoma is a rare tumor that usually starts in the cells of one of your adrenal glands. Although they are usually <a href='https://www.nlm.nih.gov/medlineplus/benigntumors.html'>benign</a>, pheochromocytomas often cause the adrenal gland to make too many hormones. This can lead to high blood pressure and cause symptoms such as </p> <ul> <li>Headaches</li> <li>Sweating</li> <li>Pounding of the heart</li> <li>Being shaky</li> <li>Being extremely pale</li> </ul> <p>Sometimes pheochromocytoma is part of another condition called multiple endocrine neoplasia syndrome (MEN). People with MEN often have other cancers and other problems involving hormones. </p> <p>Doctors use lab tests and imaging tests to diagnose it. Surgery is the most common treatment. Other options include radiation therapy, chemotherapy, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells.</p> <p >NIH: National Cancer Institute</p>|HPO2016_07_04:Pheochromocytomas (also known as chromaffin tumors) produce, store, and secrete catecholamines. Pheochromocytomas usually originate from the adrenal medulla but may also develop from chromaffin cells in or about sympathetic ganglia. A common symptom of pheochromocytoma is hypertension owing to release of catecholamines. [HPO:probinson]|HPO2016_07_04:Pheochromocytoma originating from the adrenal medulla. [HPO:curators]|CSP2006:usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia; the cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent.|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA|CHV2011_02:A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA
Me Sh Disease Class
Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms
Umls Semantic Type Name
FindingNeoplastic Process