DiseaseID 4845

副蛋白血症

disease

NCI2016_02D:A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Paraproteinemias may be seen in conjunction with various carcinomas, chronic inflammatory and infectious

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Disease: 1Symptom: 7Target: 12Links: 19
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Record Fields

Scalar fields from the final disease record.

Disease Id
4845
Core Entity Id
61258
Source Entity Count
1
Preferred Name
Paraproteinemias
Name Cn
副蛋白血症
Name Pinyin
Fu Dan Bai Xue Zheng
Name En
Paraproteinemias
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Immune System Diseases; Hemic and Lymphatic DiseasesNeoplasms
Do Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Hpo Class
Abnormality of metabolism/homeostasis; Abnormality of the immune system; Abnormal cellular phenotype
Mesh Class Name
Immune System Diseases; Hemic and Lymphatic DiseasesNeoplasms
Hpo Class Name
Abnormality of metabolism/homeostasis; Abnormality of the immune system; Abnormal cellular phenotype
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Disease Definition
NCI2016_02D:A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Paraproteinemias may be seen in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases. --2004|MSH2017_2016_08_12:A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Paraproteinemias
Role
preferred
Name
Monoclonal Gammopathy Of Undetermined Significance
Role
preferred
Name
Plasma Cell Neoplasm
Role
preferred
Name
Monoclonal Gammapathies
Role
preferred
Name
Plasma Cell Dyscrasia
Role
preferred
Name
Dyscrasia, Plasma Cell
Role
alias
Name
Monoclonal Gammopathy
Role
alias
Name
Monoclonal Gammopathy of Uncertain Significance
Role
alias
Name
Monoclonal Hypergammaglobulinemia
Role
alias
Name
Neoplasms, Plasma Cell
Role
alias
Name
Paraproteinemia
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0031047
Herb
HBDIS001964HBDIS002303HBDIS012702HBDIS012703HBDIS018599
Me Sh
D008998D010265D054219
Umls
C0026470C0030489C1959632
Icd10
D47.2
Sym Map
SMDE11075SMDE11937SMDE12209
Do Class
DOID:14566DOID:7
Dis Ge Net
C0026470C0030489C1136084C1136085C1959632
Umls Sty
T047T191
Hpo Class
HP:0001939HP:0002715HP:0025354
Me Sh Class
C04C15C20
Tcmbank Disease
263532683627438308466962
Itcmdb Generated
ITX-DISEASE-E48E65903435

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Disease Type
diseasegroup
Hpo Class Name
Abnormality of metabolism/homeostasis; Abnormality of the immune system; Abnormal cellular phenotype
Do Disease Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Abnormality of metabolism/homeostasis; Abnormality of the immune system; Abnormal cellular phenotype
Umls Disease Type
Disease or SyndromeNeoplastic Process
Disease Definition
NCI2016_02D:A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Paraproteinemias may be seen in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases. --2004|MSH2017_2016_08_12:A group of related diseases characterized by an unbalanced or disproportionate proliferation of immunoglobulin-producing cells, usually from a single clone. These cells frequently secrete a structurally homogeneous immunoglobulin (M-component) and/or an abnormal immunoglobulin.NCI2016_NCI-GLOSS_1602D:A benign condition in which there is a higher-than-normal level of a protein called M protein in the blood. Patients with MGUS are at an increased risk of developing cancer.|NCI2016_02D:A plasma cell disorder in which an abnormal amount of a single immunoglobulin is present in the serum. Up to 25% of cases of monoclonal gammopathy of undetermined significance (MGUS) progress to a B-cell malignancy or myeloma. MGUS may occur in conjunction with various carcinomas, chronic inflammatory and infectious conditions, and other diseases.|MSH2017_2016_08_12:Conditions characterized by the presence of M protein (Monoclonal protein) in serum or urine without clinical manifestations of plasma cell dyscrasia.NCI2016_NCI-GLOSS_1602D:A tumor that begins in plasma cells (white blood cells that produce antibodies). Multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), and plasmacytoma are types of plasma cell tumors.|NCI2016_CDISC_1602D:A malignant neoplasm composed of plasma cells.|NCI2016_02D:A clonal proliferation of immunoglobulin-secreting plasma cells. This category includes plasma cell myeloma, plasma cell leukemia, plasmacytoma, monoclonal immunoglobulin deposition disease, and monoclonal gammopathy of undetermined significance.|MSH2017_2016_08_12:Neoplasms associated with a proliferation of a single clone of PLASMA CELLS and characterized by the secretion of PARAPROTEINS.|CSP2006:new abnormal plasma cells that grow by excessive cellular division and proliferation more rapidly than normal and continue to grow after the stimuli that initiated the new growth cease.
Me Sh Disease Class
Immune System Diseases; Hemic and Lymphatic DiseasesNeoplasms
Dis Ge Net Disease Type
diseasegroup
Disease Class Name Me Sh
Immune System Diseases; Hemic and Lymphatic DiseasesNeoplasms
Umls Semantic Type Name
Disease or SyndromeNeoplastic Process