DiseaseID 4733

神经梅毒

disease

NCI2016_02D:A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence

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Disease: 1Symptom: 8Target: 12Links: 20
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Record Fields

Scalar fields from the final disease record.

Disease Id
4733
Core Entity Id
61126
Source Entity Count
1
Preferred Name
Neurosyphilis
Name Cn
神经梅毒
Name Pinyin
Shen Jing Mei Du
Name En
Neurosyphilis
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Infections; Nervous System DiseasesMale Urogenital Diseases; Infections; Female Urogenital Diseases and Pregnancy Complications
Do Class
disease of anatomical entity; disease by infectious agent
Hpo Class
Mesh Class Name
Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital DiseasesInfections; Nervous System Diseases
Hpo Class Name
Do Class Name
disease of anatomical entity; disease by infectious agent
Disease Definition
NCI2016_02D:A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence, dementia, and degeneration of the joints.|MSH2017_2016_08_12:Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Neurosyphilis
Role
preferred
Name
General Paralysis
Role
preferred
Name
Juvenile Neurosyphilis Unspec.
Role
preferred
Name
Tabes Dorsalis
Role
preferred
Name
Neurosyphilis, Asymptomatic
Role
preferred
Name
Neurosyphilis, Symptomatic
Role
preferred
Name
Syphilis, Tertiary
Role
preferred
Name
Syphilitic Gumma
Role
preferred
Name
Asymptomatic Neurosyphilis
Role
alias
Name
Late Congenital Syphilis
Role
alias
Name
Late Syphilis
Role
alias
Name
Late Syphilis, Unspecified
Role
alias
Name
Neurosyphilis, Unspecified
Role
alias
Name
Symptomatic Neurosyphilis
Role
alias
Name
Tertiary Neurosyphilis
Role
alias
Name
Tertiary Syphilis
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Herb
HBDIS002125HBDIS002897HBDIS003751HBDIS003752HBDIS004313HBDIS009727HBDIS028306
Me Sh
D009494D013606
Umls
C0027927C0039223C0153132C0205858
Icd10
A50.4A50.40A52A52.1A52.11A52.17A52.2A52.3A52.9
Sym Map
SMDE08976SMDE10134SMDE11463SMDE13790
Do Class
DOID:0050117DOID:7
Dis Ge Net
C0027927C0039223C0153167C0153188C0205858C0221385C0494053
Umls Sty
T047
Me Sh Class
C01C10C12C13
Tcmbank Disease
114416030164702904744517556
Itcmdb Generated
ITX-DISEASE-0B8E91D75263ITX-DISEASE-F0B84B4C5427

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity; disease by infectious agent
Disease Type
disease
Do Disease Class
disease of anatomical entity; disease by infectious agent
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_02D:A form of neurosyphilis characterized by slowly progressive degeneration of the spinal cord. Signs and symptoms include pain, ataxia, loss of coordination, personality changes, blindness, urinary incontinence, dementia, and degeneration of the joints.|MSH2017_2016_08_12:Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)NCI2016_02D:Infection of the brain or spinal cord by Treponema pallidum. It occurs many years following the original infection which remained untreated. Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia.|MSH2017_2016_08_12:Infections of the central nervous system caused by TREPONEMA PALLIDUM which present with a variety of clinical syndromes. The initial phase of infection usually causes a mild or asymptomatic meningeal reaction. The meningovascular form may present acutely as BRAIN INFARCTION. The infection may also remain subclinical for several years. Late syndromes include general paresis; TABES DORSALIS; meningeal syphilis; syphilitic OPTIC ATROPHY; and spinal syphilis. General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. (Adams et al., Principles of Neurology, 6th ed, pp722-8)
Me Sh Disease Class
Infections; Nervous System DiseasesMale Urogenital Diseases; Infections; Female Urogenital Diseases and Pregnancy Complications
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital DiseasesInfections; Nervous System Diseases
Umls Semantic Type Name
Disease or Syndrome