DiseaseID 4664

重症肌无力

disease

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Disease: 1Symptom: 12Target: 12Links: 24

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Record Fields

Scalar fields from the final disease record.

Disease Id: 4664
Core Entity Id: 61045
Source Entity Count: 1
Preferred Name: Myasthenia Gravis
Name Cn: 重症肌无力
Name Pinyin: Zhong Zheng Ji Wu Li
Name En: Myasthenia Gravis
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Nervous System Diseases; Immune System Diseases; Neoplasms
Do Class: disease of anatomical entity
Hpo Class
Mesh Class Name: Neoplasms; Immune System Diseases; Nervous System Diseases
Hpo Class Name
Do Class Name: disease of anatomical entity
Disease Definition: NCI2016_NCI-GLOSS_1602D:A disease in which antibodies made by a person's immune system prevent certain nerve-muscle interactions. It causes weakness in the arms and legs, vision problems, and drooping eyelids or head. It may also cause paralysis and problems with swallowing, talking, climbing stairs, lifting things, and getting up from a sitting position. The muscle weakness gets worse during activity, and improves after periods of rest.|NCI2016_02D:A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction.|MSH2017_2016_08_12:A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)|MEDLINEPLUS_20151021:Myasthenia gravis is disease that causes weakness in the muscles under your control. It happens because of a problem in communication between your nerves and muscles. Myasthenia gravis is an <a href='https://www.nlm.nih.gov/medlineplus/autoimmunediseases.html'>autoimmune disease</a>. Your body's own immune system makes antibodies that block or change some of the nerve signals to your muscles. This makes your muscles weaker. Common symptoms are trouble with eye and eyelid movement, facial expression and swallowing. But it can also affect other muscles. The weakness gets worse with activity, and better with rest.. There are medicines to help improve nerve-to-muscle messages and make muscles stronger. With treatment, the muscle weakness often gets much better. Other drugs keep your body from making so many abnormal antibodies. There are also treatments which filter abnormal antibodies from the blood or add healthy antibodies from donated blood. Sometimes surgery to take out the thymus gland helps. For some people, myasthenia gravis can go into remission and they do not need medicines. The remission can be temporary or permanent. If you have myasthenia gravis, it is important to follow your treatment plan. If you do, you can expect your life to be normal or close to it. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:disease characterized by progressive weakness and exhaustibility of voluntary muscles without atrophy or sensory disturbance and caused by an autoimmune attack on acetylcholine receptors at the neuromuscular junction.
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Myasthenia Gravis

Role

preferred

Name

Myasthenia Gravis, Generalized

Role

preferred

Name

Myasthenia Gravis, Ocular

Role

preferred

Cross References

Trusted external identifiers retained for this final record.

Herb

HBDIS002009HBDIS011245HBDIS011246

Me Sh

D009157

Omim

254200

Umls

C0026896

Icd10

G70.0G70.00

Sym Map

SMDE11187

Do Class

DOID:7

Dis Ge Net

C0026896C0751339C0751340

Umls Sty

T047

Me Sh Class

C04C10C20

Tcmbank Disease

10921365423588

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Do Disease Class

disease of anatomical entity

Umls Disease Type

Disease or Syndrome

Disease Definition

NCI2016_NCI-GLOSS_1602D:A disease in which antibodies made by a person's immune system prevent certain nerve-muscle interactions. It causes weakness in the arms and legs, vision problems, and drooping eyelids or head. It may also cause paralysis and problems with swallowing, talking, climbing stairs, lifting things, and getting up from a sitting position. The muscle weakness gets worse during activity, and improves after periods of rest.|NCI2016_02D:A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction.|MSH2017_2016_08_12:A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)|MEDLINEPLUS_20151021:Myasthenia gravis is disease that causes weakness in the muscles under your control. It happens because of a problem in communication between your nerves and muscles. Myasthenia gravis is an <a href='https://www.nlm.nih.gov/medlineplus/autoimmunediseases.html'>autoimmune disease</a>. Your body's own immune system makes antibodies that block or change some of the nerve signals to your muscles. This makes your muscles weaker. Common symptoms are trouble with eye and eyelid movement, facial expression and swallowing. But it can also affect other muscles. The weakness gets worse with activity, and better with rest.. There are medicines to help improve nerve-to-muscle messages and make muscles stronger. With treatment, the muscle weakness often gets much better. Other drugs keep your body from making so many abnormal antibodies. There are also treatments which filter abnormal antibodies from the blood or add healthy antibodies from donated blood. Sometimes surgery to take out the thymus gland helps. For some people, myasthenia gravis can go into remission and they do not need medicines. The remission can be temporary or permanent. If you have myasthenia gravis, it is important to follow your treatment plan. If you do, you can expect your life to be normal or close to it. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:disease characterized by progressive weakness and exhaustibility of voluntary muscles without atrophy or sensory disturbance and caused by an autoimmune attack on acetylcholine receptors at the neuromuscular junction.

Me Sh Disease Class

Nervous System Diseases; Immune System Diseases; Neoplasms

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Neoplasms; Immune System Diseases; Nervous System Diseases

Umls Semantic Type Name

Disease or Syndrome