DiseaseID 4648

多发性硬化

disease

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Disease: 1Experiment: 6Formula: 1Herb: 3Symptom: 12Target: 25Links: 47

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Record Fields

Scalar fields from the final disease record.

Disease Id: 4648
Core Entity Id: 61027
Source Entity Count: 1
Preferred Name: Multiple Sclerosis
Name Cn: 多发性硬化
Name Pinyin: Duo Fa Xing Ying Hua
Name En: Multiple Sclerosis
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Immune System Diseases; Nervous System Diseases
Do Class: disease of anatomical entity
Hpo Class
Mesh Class Name: Immune System Diseases; Nervous System Diseases
Hpo Class Name
Do Class Name: disease of anatomical entity
Disease Definition: NCI2016_NICHD_1602D:An autoimmune demyelinating disease characterized by a relapsing-remitting or progressive pattern of central nervous system impairment.|NCI2016_NCI-GLOSS_1602D:A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and bladder control. Multiple sclerosis is thought to be an autoimmune disease in which the body's immune system destroys myelin. Myelin is a substance that contains both protein and fat (lipid), serving as a nerve insulator and helping in the transmission of nerve signals.|NCI2016_02D:A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.|MSH2017_2016_08_12:An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)|MEDLINEPLUS_20151021:Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include <ul> <li>Visual disturbances</li> <li>Muscle weakness</li> <li>Trouble with coordination and balance</li> <li>Sensations such as numbness, prickling, or "pins and needles" </li> <li>Thinking and memory problems</li> </ul> No one knows what causes MS. It may be an autoimmune disease, which happens when your immune system attacks healthy cells in your body by mistake. Multiple sclerosis affects women more than men. It often begins between the ages of 20 and 40. Usually, the disease is mild, but some people lose the ability to write, speak, or walk. There is no single test for MS. Doctors use a medical history, physical exam, neurological exam, MRI, and other tests to diagnose it. There is no cure for MS, but medicines may slow it down and help control symptoms. Physical and occupational therapy may also help. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:chronic disease characterized by presence of numerous areas of demyelination in the central nervous system with symptoms such as weakness, incoordination, paresthesis, and speech disturbances; the etiology is unknown.
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Multiple Sclerosis

Role

preferred

Name

Multiple Sclerosis, Acute Fulminating

Role

preferred

Cross References

Trusted external identifiers retained for this final record.

Herb

HBDIS001992HBDIS011234

Me Sh

D009103

Umls

C0026769

Icd10

G35

Sym Map

SMDE11153

Do Class

DOID:7

Dis Ge Net

C0026769C0751324

Umls Sty

T047

Me Sh Class

C10C20

Etcm Disease

Multiple Sclerosis

Tcmbank Disease

18129295849579

Itcmdb Generated

ITX-DISEASE-0E507D9C0652ITX-DISEASE-329F917D75F1

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Page Title

Disease Multiple Sclerosis Details page

Do Class Name

disease of anatomical entity

Disease Type

disease

Do Disease Class

disease of anatomical entity

Umls Disease Type

Disease or Syndrome

Basic Information

Disease Name

Multiple Sclerosis

Global Category

Genetic diseases;Rare diseases

Anatomical Category

Immune diseases;Neuronal diseases

Disease Definition

NCI2016_NICHD_1602D:An autoimmune demyelinating disease characterized by a relapsing-remitting or progressive pattern of central nervous system impairment.|NCI2016_NCI-GLOSS_1602D:A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and bladder control. Multiple sclerosis is thought to be an autoimmune disease in which the body's immune system destroys myelin. Myelin is a substance that contains both protein and fat (lipid), serving as a nerve insulator and helping in the transmission of nerve signals.|NCI2016_02D:A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers.|MSH2017_2016_08_12:An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)|MEDLINEPLUS_20151021:Multiple sclerosis (MS) is a nervous system disease that affects your brain and spinal cord. It damages the myelin sheath, the material that surrounds and protects your nerve cells. This damage slows down or blocks messages between your brain and your body, leading to the symptoms of MS. They can include <ul> <li>Visual disturbances</li> <li>Muscle weakness</li> <li>Trouble with coordination and balance</li> <li>Sensations such as numbness, prickling, or "pins and needles" </li> <li>Thinking and memory problems</li> </ul> No one knows what causes MS. It may be an autoimmune disease, which happens when your immune system attacks healthy cells in your body by mistake. Multiple sclerosis affects women more than men. It often begins between the ages of 20 and 40. Usually, the disease is mild, but some people lose the ability to write, speak, or walk. There is no single test for MS. Doctors use a medical history, physical exam, neurological exam, MRI, and other tests to diagnose it. There is no cure for MS, but medicines may slow it down and help control symptoms. Physical and occupational therapy may also help. NIH: National Institute of Neurological Disorders and Stroke|CSP2006:chronic disease characterized by presence of numerous areas of demyelination in the central nervous system with symptoms such as weakness, incoordination, paresthesis, and speech disturbances; the etiology is unknown.

Me Sh Disease Class

Immune System Diseases; Nervous System Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Immune System Diseases; Nervous System Diseases

Umls Semantic Type Name

Disease or Syndrome