DiseaseID 4621

激惹心脏

disease

MSH2017_2016_08_12:A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be D

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Disease: 1Symptom: 12Target: 12Links: 24
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Record Fields

Scalar fields from the final disease record.

Disease Id
4621
Core Entity Id
60996
Source Entity Count
1
Preferred Name
Irritable Heart
Name Cn
激惹心脏
Name Pinyin
Ji Re Xin Zang
Name En
Irritable Heart
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Congenital Abnormality
Disgenet Type
disease
Mesh Class
Cardiovascular DiseasesCardiovascular Diseases; Nervous System DiseasesMental DisordersNervous System DiseasesNervous System Diseases; Pathological Conditions, Signs and Symptoms
Do Class
disease of anatomical entitydisease of anatomical entity; genetic diseasedisease of mental health; disease of anatomical entity; genetic disease
Hpo Class
Abnormality of the cardiovascular systemAbnormality of the nervous system; Abnormality of the cardiovascular system
Mesh Class Name
Cardiovascular DiseasesMental DisordersNervous System DiseasesNervous System Diseases; Cardiovascular DiseasesPathological Conditions, Signs and Symptoms; Nervous System Diseases
Hpo Class Name
Abnormality of the cardiovascular systemAbnormality of the nervous system; Abnormality of the cardiovascular system
Do Class Name
disease of anatomical entitygenetic disease; disease of anatomical entitygenetic disease; disease of anatomical entity; disease of mental health
Disease Definition
MSH2017_2016_08_12:A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be DIZZINESS, tremulousness, SWEATING, and INSOMNIA. Neurocirculatory asthenia is most typically seen as a form of anxiety disorder.
Version
v1
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Irritable Heart
Role
preferred
Name
Mitral Valve Prolapse Syndrome
Role
preferred
Name
Orthostatic Intolerance
Role
preferred
Name
Postural Orthostatic Tachycardia Syndrome
Role
preferred
Name
Pure Autonomic Failure
Role
preferred
Name
Syndrome Effort
Role
preferred
Name
Familial Mitral Valve Prolapse
Role
preferred
Name
Hypotension, Orthostatic
Role
preferred
Name
MITRAL VALVE PROLAPSE, MYXOMATOUS 2
Role
preferred
Name
MULTIPLE SYSTEM ATROPHY 1, SUSCEPTIBILITY TO
Role
preferred
Name
MYXOMATOUS MITRAL VALVE PROLAPSE 1
Role
preferred
Name
Mitral Valve Dysplasia
Role
preferred
Name
Neurocirculatory Asthenia
Role
preferred
Name
Autonomic Failure, Pure
Role
alias
Name
Intolerance, Orthostatic
Role
alias
Name
Mitral (Valve) Prolapse
Role
alias
Name
Mitral Valve Prolapse
Role
alias
Name
Mitral Valve Prolapse 1
Role
alias
Name
Mitral Valve Prolapse 2
Role
alias
Name
Mitral Valve Prolapse, Familial
Role
alias
Name
Mitral Valve Prolapse, Myxomatous 1
Role
alias
Name
Myxomatous Mitral Valve Degeneration
Role
alias
Name
Myxomatous Mitral Valve Prolapse 2
Role
alias
Name
Orthostatic Hypotension
Role
alias
Name
Postural Hypotension
Role
alias
Name
SOLDIERS HEART
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0001278HP:0001634HP:0004764
Herb
HBDIS001503HBDIS001957HBDIS002110HBDIS007821HBDIS008737HBDIS013319HBDIS014503HBDIS015270HBDIS015985HBDIS020152HBDIS022122HBDIS027763
Me Sh
D007024D008945D009449D054970D054971D054972
Omim
146500604715
Umls
C0020651C0026267C0027821C0393911C1299624C1535893C2930833
Icd10
I34.1I95.1
Sym Map
SMDE00461SMDE09725SMDE11045SMDE12371SMDE12613SMDE13764
Do Class
DOID:150DOID:630DOID:7
Dis Ge Net
C0020651C0026267C0027821C0340364C0393911C1299624C1535893C1834819C1843003C2930833C3714927C4721438
Umls Sty
T019T033T047
Hpo Class
HP:0000707HP:0001626
Me Sh Class
C10C14C23F03
Tcmbank Disease
109812039122601241913558135931826118328277922974344128918
Itcmdb Generated
ITX-DISEASE-CA561C4D153E

Attributes

Merged source attributes and domain-specific metadata.

Version
v1v2
Suppress
0
Do Class Name
disease of anatomical entitygenetic disease; disease of anatomical entitygenetic disease; disease of anatomical entity; disease of mental health
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of the cardiovascular systemAbnormality of the nervous system; Abnormality of the cardiovascular system
Do Disease Class
disease of anatomical entitydisease of anatomical entity; genetic diseasedisease of mental health; disease of anatomical entity; genetic disease
Hpo Disease Class
Abnormality of the cardiovascular systemAbnormality of the nervous system; Abnormality of the cardiovascular system
Umls Disease Type
Congenital AbnormalityDisease or SyndromeFinding
Disease Definition
MSH2017_2016_08_12:A clinical syndrome characterized by palpitation, SHORTNESS OF BREATH, labored breathing, subjective complaints of effort and discomfort, all following slight PHYSICAL EXERTION. Other symptoms may be DIZZINESS, tremulousness, SWEATING, and INSOMNIA. Neurocirculatory asthenia is most typically seen as a form of anxiety disorder.MSH2017_2016_08_12:A degenerative disease of the AUTONOMIC NERVOUS SYSTEM that is characterized by idiopathic ORTHOSTATIC HYPOTENSION and a greatly reduced level of CATECHOLAMINES. No other neurological deficits are present.NCI2016_02D:A condition characterized by development of symptoms while standing. It is an autonomic nervous system disorder and the symptoms are relieved once the person sits back down. Symptoms include heart palpitations, sweating, anxiety, lightheadedness, hyperpnea, anxiety, and blurred vision.|MSH2017_2016_08_12:Symptoms of cerebral hypoperfusion or autonomic overaction which develop while the subject is standing, but are relieved on recumbency. Types of this include NEUROCARDIOGENIC SYNCOPE; POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME; and neurogenic ORTHOSTATIC HYPOTENSION. (From Noseworthy, JH., Neurological Therapeutics Principles and Practice, 2007, p2575-2576)NCI2016_02D:A syndrome characterized by orthostatic intolerance resulting in tachycardia, often accompanied by a decrease in the blood pressure. It occurs when individuals change from the supine position to an upright position. Other signs and symptoms include lightheadedness, fainting, fatigue and muscle weakness.|MSH2017_2016_08_12:A syndrome of ORTHOSTATIC INTOLERANCE combined with excessive upright TACHYCARDIA, and usually without associated ORTHOSTATIC HYPOTENSION. All variants have in common an excessively reduced venous return to the heart (central HYPOVOLEMIA) while upright.NCI2016_FDA_1602D:Prolapse of the mitral valve, often with regurgitation, associated with myxomatous proliferation of the leaflets of the mitral valve.|NCI2016_02D:A fairly common and often benign valvular heart disorder characterized by redundancy or hooding of mitral valve leaflets so that they prolapse into the left atrium, often causing mitral regurgitation. It is often a symptomless condition but may be marked by varied symptoms (e.g. chest pain, fatigue, dizziness, dyspnea, or palpitations) leading in some cases to endocarditis or ventricular tachycardia.|MSH2017_2016_08_12:Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.|MEDLINEPLUS_20151021:<p>Mitral valve prolapse (MVP) occurs when one of your heart's valves doesn't work properly. The flaps of the valve are "floppy" and don't close tightly. Most people who have the condition are born with it. It also tends to run in families.</p> <p>Most of the time, MVP doesn't cause any problems. Rarely, blood can leak the wrong way through the floppy valve. This can cause</p> <ul> <li>Palpitations (feelings that your heart is skipping a beat, fluttering, or beating too hard or too fast)</li> <li>Shortness of breath</li> <li>Cough</li> <li>Fatigue, dizziness, or anxiety</li> <li>Migraine headaches</li> <li>Chest discomfort</li> </ul> <p>Most people who have mitral valve prolapse (MVP) don't need treatment because they don't have symptoms and complications. If you need treatment for MVP, medicines can help relieve symptoms or prevent complications. Very few people will need surgery to repair or replace the mitral valve.</p> <p>MVP puts you at risk for infective <a href='https://www.nlm.nih.gov/medlineplus/endocarditis.html'>endocarditis</a>, a kind of heart infection. To prevent it, doctors used to prescribe antibiotics before dental work or certain surgeries. Now, only people at high risk of endocarditis need the antibiotics.</p> <p >NIH: National Heart, Lung, and Blood Institute</p>|HPO2016_07_04:One or both of the leaflets (cusps) of the mitral valve bulges back into the left atrium upon contraction of the left ventricle. [HPO:probinson]NCI2016_NICHD_1602D:A sudden fall in blood pressure upon rising to a standing position.|NCI2016_02D:Sudden fall of the blood pressure of at least 20/10 mm Hg when a person stands up.|MSH2017_2016_08_12:A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.|HPO2016_07_04:A form of hypotension characterized by a sudden fall in blood pressure that occurs when a person assumes a standing position. [HPO:probinson]|CSP2006:fall in blood pressure associated with dizziness, syncope and blurred vision occurring upon standing or when standing motionless in a fixed position.
Me Sh Disease Class
Cardiovascular DiseasesCardiovascular Diseases; Nervous System DiseasesMental DisordersNervous System DiseasesNervous System Diseases; Pathological Conditions, Signs and Symptoms
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Cardiovascular DiseasesMental DisordersNervous System DiseasesNervous System Diseases; Cardiovascular DiseasesPathological Conditions, Signs and Symptoms; Nervous System Diseases
Umls Semantic Type Name
Congenital AbnormalityDisease or SyndromeFinding