DiseaseID 4609

高铁血红蛋白血症

disease

NCI2016_NCI-GLOSS_1602D:A condition in which a higher-than-normal amount of methemoglobin is found in the blood. Methemoglobin is a form of hemoglobin that cannot carry oxygen. In methemoglobinemia, tissues cannot get en

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Disease: 1Symptom: 6Target: 12Links: 18
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Record Fields

Scalar fields from the final disease record.

Disease Id
4609
Core Entity Id
60984
Source Entity Count
2
Preferred Name
Methemoglobinemia
Name Cn
高铁血红蛋白血症
Name Pinyin
Gao Tie Xue Hong Dan Bai Xue Zheng
Name En
Methemoglobinemia
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Hemic and Lymphatic Diseases
Do Class
disease of anatomical entity
Hpo Class
Abnormality of blood and blood-forming tissues
Mesh Class Name
Hemic and Lymphatic Diseases
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Class Name
disease of anatomical entity
Disease Definition
NCI2016_NCI-GLOSS_1602D:A condition in which a higher-than-normal amount of methemoglobin is found in the blood. Methemoglobin is a form of hemoglobin that cannot carry oxygen. In methemoglobinemia, tissues cannot get enough oxygen. Symptoms may include headache, dizziness, fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, loss of muscle coordination, and blue-colored skin. Methemoglobinemia can be caused by injury or being exposed to certain drugs, chemicals, or foods. It can also be an inherited condition.|NCI2016_02D:An inherited or acquired condition characterized by abnormally increased levels of methemoglobin in the blood.|MSH2017_2016_08_12:The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)|HPO2016_07_04:Abnormally increased levels of Methemoglobinemia in the blood. In this form of hemoglobin, there is an oxidized ferric iron (Fe +3) rather than the reduced ferrous form (Fe 2+) that is normally found in hemoglobin. Methemoglobin has a reduced affinity for oxygen, resulting in a reduced ability to release oxygen to tissues. [HPO:probinson]
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Methemoglobinemia
Role
preferred
Name
Methaemoglobinaemia
Role
alias
Name
Methaemoglobinaemia, Unspecified
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0012119
Herb
HBDIS001939
Me Sh
D008708
Umls
C0025637
Icd10
D74D74.9
Sym Map
SMDE10961
Do Class
DOID:7
Dis Ge Net
C0025637
Umls Sty
T047
Hpo Class
HP:0001871
Me Sh Class
C15
Tcmbank Disease
2014129024
Itcmdb Generated
ITX-DISEASE-3BF8CD225AFF

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity
Disease Type
disease
Hpo Class Name
Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of blood and blood-forming tissues
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_NCI-GLOSS_1602D:A condition in which a higher-than-normal amount of methemoglobin is found in the blood. Methemoglobin is a form of hemoglobin that cannot carry oxygen. In methemoglobinemia, tissues cannot get enough oxygen. Symptoms may include headache, dizziness, fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, loss of muscle coordination, and blue-colored skin. Methemoglobinemia can be caused by injury or being exposed to certain drugs, chemicals, or foods. It can also be an inherited condition.|NCI2016_02D:An inherited or acquired condition characterized by abnormally increased levels of methemoglobin in the blood.|MSH2017_2016_08_12:The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)|HPO2016_07_04:Abnormally increased levels of Methemoglobinemia in the blood. In this form of hemoglobin, there is an oxidized ferric iron (Fe +3) rather than the reduced ferrous form (Fe 2+) that is normally found in hemoglobin. Methemoglobin has a reduced affinity for oxygen, resulting in a reduced ability to release oxygen to tissues. [HPO:probinson]
Me Sh Disease Class
Hemic and Lymphatic Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Hemic and Lymphatic Diseases
Umls Semantic Type Name
Disease or Syndrome