ITCMDBv1
DiseaseID 4494

肝硬化

disease

NCI2016_NICHD_1602D:A chronic degenerative disease of the liver characterized by parenchymal nodularity and fibrosis.|NCI2016_NCI-GLOSS_1602D:A type of chronic, progressive liver disease in which liver cells are replaced

Back to Browse

Relationship Network

Interactive first-hop connections across herbs, ingredients, formulas, targets, diseases, symptoms, syndromes, evidence, and monographs.

Click a node to open it in a new tab
Disease: 1Experiment: 2Symptom: 12Target: 12Links: 26
Arranging relationship network...

Record Fields

Scalar fields from the final disease record.

Disease Id
4494
Core Entity Id
60850
Source Entity Count
1
Preferred Name
Liver Cirrhosis
Name Cn
肝硬化
Name Pinyin
Gan Ying Hua
Name En
Liver Cirrhosis
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Disease or Syndrome
Disgenet Type
disease
Mesh Class
Digestive System Diseases; Pathological Conditions, Signs and Symptoms
Do Class
disease of anatomical entity
Hpo Class
Abnormality of the digestive system
Mesh Class Name
Pathological Conditions, Signs and Symptoms; Digestive System Diseases
Hpo Class Name
Abnormality of the digestive system
Do Class Name
disease of anatomical entity
Disease Definition
NCI2016_NICHD_1602D:A chronic degenerative disease of the liver characterized by parenchymal nodularity and fibrosis.|NCI2016_NCI-GLOSS_1602D:A type of chronic, progressive liver disease in which liver cells are replaced by scar tissue.|NCI2016_02D:A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.|MSH2017_2016_08_12:Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.|MEDLINEPLUS_20151021:<p>Cirrhosis is scarring of the liver. Scar tissue forms because of injury or long-term disease. Scar tissue cannot do what healthy liver tissue does - make protein, help fight infections, clean the blood, help digest food and store energy. Cirrhosis can lead to </p> <ul> <li>Easy bruising or bleeding, or nosebleeds</li> <li>Swelling of the abdomen or legs </li> <li>Extra sensitivity to medicines</li> <li>High blood pressure in the vein entering the liver</li> <li>Enlarged veins called varices in the esophagus and stomach. Varices can bleed suddenly.</li> <li> Kidney failure</li> <li>Jaundice</li> <li>Severe itching</li> <li>Gallstones</li> </ul> <p>A small number of people with cirrhosis get <a href='https://www.nlm.nih.gov/medlineplus/livercancer.html'>liver cancer</a>.</p> <p>Your doctor will diagnose cirrhosis with blood tests, imaging tests, or a biopsy.</p> <p>Cirrhosis has many causes. In the United States, the most common causes are chronic <a href='https://www.nlm.nih.gov/medlineplus/alcoholismandalcoholabuse.html'>alcoholism</a> and <a href='https://www.nlm.nih.gov/medlineplus/hepatitis.html'>hepatitis</a>. Nothing will make the scar tissue disappear, but treating the cause can keep it from getting worse. If too much scar tissue forms, you may need to consider a <a href='https://www.nlm.nih.gov/medlineplus/livertransplantation.html'>liver transplant</a>. </p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function. [HPO:probinson]|CSP2006:liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Liver Cirrhosis
Role
preferred
Name
Fibrosis, Liver
Role
preferred
Name
Cirrhosis
Role
alias
Name
Hepatic Cirrhosis
Role
alias
Name
Hepatic Fibrosis
Role
alias
Name
Scar Tissue Replaces Healthy Tissue In The Liver
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0001394HP:0001395
Herb
HBDIS001765HBDIS005263
Icd10
K74.0
Sym Map
SMDE10482
Do Class
DOID:7
Dis Ge Net
C0023890C0239946
Umls Sty
T047
Hpo Class
HP:0025031
Me Sh Class
C06C23
Tcmbank Disease
171878829442
Itcmdb Generated
ITX-DISEASE-5DD102F1B549ITX-DISEASE-DC5F4EFF49B9

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity
Disease Type
disease
Hpo Class Name
Abnormality of the digestive system
Do Disease Class
disease of anatomical entity
Hpo Disease Class
Abnormality of the digestive system
Umls Disease Type
Disease or Syndrome
Disease Definition
NCI2016_NICHD_1602D:A chronic degenerative disease of the liver characterized by parenchymal nodularity and fibrosis.|NCI2016_NCI-GLOSS_1602D:A type of chronic, progressive liver disease in which liver cells are replaced by scar tissue.|NCI2016_02D:A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy.|MSH2017_2016_08_12:Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.|MEDLINEPLUS_20151021:<p>Cirrhosis is scarring of the liver. Scar tissue forms because of injury or long-term disease. Scar tissue cannot do what healthy liver tissue does - make protein, help fight infections, clean the blood, help digest food and store energy. Cirrhosis can lead to </p> <ul> <li>Easy bruising or bleeding, or nosebleeds</li> <li>Swelling of the abdomen or legs </li> <li>Extra sensitivity to medicines</li> <li>High blood pressure in the vein entering the liver</li> <li>Enlarged veins called varices in the esophagus and stomach. Varices can bleed suddenly.</li> <li> Kidney failure</li> <li>Jaundice</li> <li>Severe itching</li> <li>Gallstones</li> </ul> <p>A small number of people with cirrhosis get <a href='https://www.nlm.nih.gov/medlineplus/livercancer.html'>liver cancer</a>.</p> <p>Your doctor will diagnose cirrhosis with blood tests, imaging tests, or a biopsy.</p> <p>Cirrhosis has many causes. In the United States, the most common causes are chronic <a href='https://www.nlm.nih.gov/medlineplus/alcoholismandalcoholabuse.html'>alcoholism</a> and <a href='https://www.nlm.nih.gov/medlineplus/hepatitis.html'>hepatitis</a>. Nothing will make the scar tissue disappear, but treating the cause can keep it from getting worse. If too much scar tissue forms, you may need to consider a <a href='https://www.nlm.nih.gov/medlineplus/livertransplantation.html'>liver transplant</a>. </p> <p >NIH: National Institute of Diabetes and Digestive and Kidney Diseases</p>|HPO2016_07_04:A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function. [HPO:probinson]|CSP2006:liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
Me Sh Disease Class
Digestive System Diseases; Pathological Conditions, Signs and Symptoms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Pathological Conditions, Signs and Symptoms; Digestive System Diseases
Umls Semantic Type Name
Disease or Syndrome