DiseaseID 4441

里希特综合征

disease

NCI2016_NCI-GLOSS_1602D:An indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly in the blood and bone marrow. Sometimes, in later stages of the disease, cancer cells

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Disease: 1Experiment: 3Symptom: 12Target: 12Links: 27
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Record Fields

Scalar fields from the final disease record.

Disease Id
4441
Core Entity Id
60789
Source Entity Count
1
Preferred Name
Richter'S Syndrome
Name Cn
里希特综合征
Name Pinyin
Li Xi Te Zong He Zheng
Name En
Richter'S Syndrome
Name Latin
Bilingual Status
complete
Disease Type
disease
Umls Disease Type
Neoplastic Process
Disgenet Type
disease
Mesh Class
Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases
Do Class
disease of anatomical entity; disease of cellular proliferation
Hpo Class
Abnormality of the immune system; Abnormality of blood and blood-forming tissues; Neoplasm
Mesh Class Name
Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Hpo Class Name
Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Definition
NCI2016_NCI-GLOSS_1602D:An indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly in the blood and bone marrow. Sometimes, in later stages of the disease, cancer cells are found in the lymph nodes and the disease is called small lymphocytic lymphoma.|NCI2016_02D:The most common type of chronic lymphoid leukemia. It comprises 90% of chronic lymphoid leukemias in the United States. Morphologically, the neoplastic cells are small, round B-lymphocytes. This type of leukemia is not considered to be curable with available therapy. (WHO, 2001)|MSH2017_2016_08_12:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.|MEDLINEPLUS_20151021:<p><a href='https://www.nlm.nih.gov/medlineplus/leukemia.html'>Leukemia</a> is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In chronic lymphocytic leukemia (CLL), there are too many lymphocytes, a type of white blood cell.</p> <p>CLL is the second most common type of leukemia in adults. It often occurs during or after middle age, and is rare in children.</p> <p>Usually CLL does not cause any symptoms. If you have symptoms, they may include</p> <ul> <li>Painless swelling of the lymph nodes in the neck, underarm, stomach, or groin</li> <li>Fatigue</li> <li>Pain or a feeling of fullness below the ribs</li> <li>Fever and infection</li> <li>Weight loss</li> </ul> <p>Tests that examine the blood, bone marrow, and lymph nodes diagnose CLL. Your doctor may choose to just monitor you until symptoms appear or change. Treatments include radiation therapy, chemotherapy, surgery to remove the spleen, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells.</p> <p >NIH: National Cancer Institute</p>|HPO2016_07_04:A chronic lymphocytic/lymphatic/lymphoblastic leukemia (CLL) is a neoplastic disease characterized by proliferation and accumulation (blood, marrow and lymphoid organs) of morphologically mature but immunologically dysfunctional lymphocytes. A CLL is always a B-cell lymphocytic leukemia as there are no reports of cases of T-cell lymphocytic leukemias. [HPO:curators]|CSP2006:chronic leukemia characterized by morphologically mature but immunologically less mature lymphocytes; manifested by an abnormal accumulation of these cells in blood, bone marrow, and lymphatic tissue.
Version
v2
Suppressed
No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name
Richter'S Syndrome
Role
preferred
Name
B-CELL MALIGNANCY, LOW-GRADE
Role
preferred
Name
Chronic Lymphocytic Leukemia
Role
preferred
Name
Small Lymphocytic Lymphoma
Role
preferred
Name
Chronic Lymphatic Leukemia
Role
alias
Name
Chronic Lymphocytic Leukaemia
Role
alias
Name
Leukemia, Chronic Lymphocytic
Role
alias
Name
Leukemia, Chronic Lymphocytic, Susceptibility To, 2
Role
alias
Name
Leukemia, Lymphocytic, Chronic, B-Cell
Role
alias

Cross References

Trusted external identifiers retained for this final record.

Hpo
HP:0005550
Herb
HBDIS001695HBDIS008503HBDIS011999HBDIS018473
Me Sh
D015451
Omim
151400
Umls
C0023434
Icd10
C91.1C91.10
Sym Map
SMDE07196
Do Class
DOID:14566DOID:7
Dis Ge Net
C0023434C0349631C0855095C1868683
Umls Sty
T191
Hpo Class
HP:0001871HP:0002664HP:0002715
Me Sh Class
C04C15C20
Tcmbank Disease
1281713668203024478

Attributes

Merged source attributes and domain-specific metadata.

Version
v2
Suppress
0
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
Do Disease Class
disease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Abnormality of the immune system; Abnormality of blood and blood-forming tissues; Neoplasm
Umls Disease Type
Neoplastic Process
Disease Definition
NCI2016_NCI-GLOSS_1602D:An indolent (slow-growing) cancer in which too many immature lymphocytes (white blood cells) are found mostly in the blood and bone marrow. Sometimes, in later stages of the disease, cancer cells are found in the lymph nodes and the disease is called small lymphocytic lymphoma.|NCI2016_02D:The most common type of chronic lymphoid leukemia. It comprises 90% of chronic lymphoid leukemias in the United States. Morphologically, the neoplastic cells are small, round B-lymphocytes. This type of leukemia is not considered to be curable with available therapy. (WHO, 2001)|MSH2017_2016_08_12:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.|MEDLINEPLUS_20151021:<p><a href='https://www.nlm.nih.gov/medlineplus/leukemia.html'>Leukemia</a> is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In chronic lymphocytic leukemia (CLL), there are too many lymphocytes, a type of white blood cell.</p> <p>CLL is the second most common type of leukemia in adults. It often occurs during or after middle age, and is rare in children.</p> <p>Usually CLL does not cause any symptoms. If you have symptoms, they may include</p> <ul> <li>Painless swelling of the lymph nodes in the neck, underarm, stomach, or groin</li> <li>Fatigue</li> <li>Pain or a feeling of fullness below the ribs</li> <li>Fever and infection</li> <li>Weight loss</li> </ul> <p>Tests that examine the blood, bone marrow, and lymph nodes diagnose CLL. Your doctor may choose to just monitor you until symptoms appear or change. Treatments include radiation therapy, chemotherapy, surgery to remove the spleen, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells.</p> <p >NIH: National Cancer Institute</p>|HPO2016_07_04:A chronic lymphocytic/lymphatic/lymphoblastic leukemia (CLL) is a neoplastic disease characterized by proliferation and accumulation (blood, marrow and lymphoid organs) of morphologically mature but immunologically dysfunctional lymphocytes. A CLL is always a B-cell lymphocytic leukemia as there are no reports of cases of T-cell lymphocytic leukemias. [HPO:curators]|CSP2006:chronic leukemia characterized by morphologically mature but immunologically less mature lymphocytes; manifested by an abnormal accumulation of these cells in blood, bone marrow, and lymphatic tissue.
Me Sh Disease Class
Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Umls Semantic Type Name
Neoplastic Process