DiseaseID 4407
Lambert-Eaton肌无力综合征
disease
NCI2016_02D:A rare autoimmune presynaptic disorder characterized by impairment of the impulse transmission at the neuromuscular junction. It affects predominantly the proximal muscles of the lower extremities, resulting
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Disease: 1Formula: 1Symptom: 4Target: 24Links: 29
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 4407
- Core Entity Id
- 60752
- Source Entity Count
- 1
- Preferred Name
- Lambert-Eaton Myasthenic Syndrome
- Name Cn
- Lambert-Eaton肌无力综合征
- Name Pinyin
- Lambert-eaton Ji Wu Li Zong He Zheng
- Name En
- Lambert-Eaton Myasthenic Syndrome
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Disease or Syndrome
- Disgenet Type
- disease
- Mesh Class
- Nervous System Diseases; Immune System Diseases; Neoplasms
- Do Class
- disease of anatomical entity
- Hpo Class
- Mesh Class Name
- Neoplasms; Immune System Diseases; Nervous System Diseases
- Hpo Class Name
- Do Class Name
- disease of anatomical entity
- Disease Definition
- NCI2016_02D:A rare autoimmune presynaptic disorder characterized by impairment of the impulse transmission at the neuromuscular junction. It affects predominantly the proximal muscles of the lower extremities, resulting in muscle weakness and fatigability. It has been associated with small cell lung carcinoma.|MSH2017_2016_08_12:An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
- Version
- v2
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Lambert-Eaton Myasthenic Syndrome
Role
preferred
Name
Eaton-Lambert Syndrome
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Herb
HBDIS001644
Me Sh
D015624
Umls
C0022972
Icd10
G70.80G73.1
Sym Map
SMDE10273
Do Class
DOID:7
Dis Ge Net
C0022972
Umls Sty
T047
Me Sh Class
C04C10C20
Etcm Disease
Lambert-Eaton Myasthenic Syndrome
Tcmbank Disease
21821
Itcmdb Generated
ITX-DISEASE-39B3FFF8D8FC
Attributes
Merged source attributes and domain-specific metadata.
Version
v2
Suppress
0
Page Title
Disease Lambert-Eaton Myasthenic Syndrome Details page
Do Class Name
disease of anatomical entity
Disease Type
disease
Do Disease Class
disease of anatomical entity
Umls Disease Type
Disease or Syndrome
Basic Information
Disease Name
Lambert-Eaton Myasthenic Syndrome
Global Category
Cancer diseases;Rare diseases
Anatomical Category
Immune diseases;Neuronal diseases;Respiratory diseases
Disease Definition
NCI2016_02D:A rare autoimmune presynaptic disorder characterized by impairment of the impulse transmission at the neuromuscular junction. It affects predominantly the proximal muscles of the lower extremities, resulting in muscle weakness and fatigability. It has been associated with small cell lung carcinoma.|MSH2017_2016_08_12:An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
Me Sh Disease Class
Nervous System Diseases; Immune System Diseases; Neoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
Neoplasms; Immune System Diseases; Nervous System Diseases
Umls Semantic Type Name
Disease or Syndrome