DiseaseID 4237

霍奇金病

disease

NCI2016_02D:A diffuse subtype of classical Hodgkin lymphoma which is rich in Hodgkin and Reed-Sternberg cells and/or depleted in non-neoplastic lymphocytes. (WHO, 2008)

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Disease: 1Symptom: 12Target: 12Links: 24

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Record Fields

Scalar fields from the final disease record.

Disease Id: 4237
Core Entity Id: 60555
Source Entity Count: 1
Preferred Name: Hodgkin Disease
Name Cn: 霍奇金病
Name Pinyin: Huo Qi Jin Bing
Name En: Hodgkin Disease
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Neoplastic Process
Disgenet Type: disease
Mesh Class: Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases
Do Class: disease of anatomical entity; disease of cellular proliferation
Hpo Class: Abnormality of blood and blood-forming tissues; Neoplasm
Mesh Class Name: Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Hpo Class Name: Neoplasm; Abnormality of blood and blood-forming tissues
Do Class Name: disease of anatomical entity; disease of cellular proliferation
Disease Definition: NCI2016_02D:A diffuse subtype of classical Hodgkin lymphoma which is rich in Hodgkin and Reed-Sternberg cells and/or depleted in non-neoplastic lymphocytes. (WHO, 2008)
Version: v2
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Hodgkin Disease

Role

preferred

Name

Hodgkin Lymphoma, Lymphocyte Depletion

Role

preferred

Name

Hodgkin Lymphoma, Nodular Lymphocyte Predominance

Role

preferred

Name

Lymphocyte Rich Classical Hodgkin Lymphoma

Role

preferred

Name

Mixed Cellularity Hodgkin Lymphoma

Role

preferred

Name

Nodular Lymphocyte Predominant Hodgkin Lymphoma

Role

preferred

Name

Adult Hodgkin Lymphoma

Role

preferred

Name

Hodgkin Lymphoma

Role

alias

Name

Hodgkin'S Disease

Role

alias

Name

Hodgkin'S Disease With Lymphocytic Depletion

Role

alias

Name

Hodgkin'S Disease With Lymphocytic Predominance

Role

alias

Name

Hodgkin'S Disease With Mixed Cellularity

Role

alias

Name

Hodgkin'S Disease, Unspecified

Role

alias

Name

Hodgkin'S Granuloma

Role

alias

Name

Hodgkin'S Lymphoma

Role

alias

Name

Hodgkin'S Lymphoma, Lymphocytic Depletion

Role

alias

Name

Hodgkin'S Lymphoma, Lymphocytic-Histiocytic Predominance

Role

alias

Name

Hodgkin'S Lymphoma, Mixed Cellularity

Role

alias

Name

Lymphocyte Depletion Hodgkin'S Lymphoma

Role

alias

Name

Lymphocyte Rich Classical Hodgkin'S Lymphoma

Role

alias

Name

Lymphocytic Depletion

Role

alias

Name

Lymphocytic Predominance

Role

alias

Name

Lymphoma, Hodgkin, Classic

Role

alias

Name

Mixed Cellularity

Role

alias

Name

Mixed Cellularity Hodgkin'S Lymphoma

Role

alias

Name

Nodular Lymphocyte-Predominant Hodgkin'S Lymphoma

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Hpo

HP:0012189

Herb

HBDIS001391HBDIS003712HBDIS003713HBDIS004473HBDIS013016HBDIS013874HBDIS019003

Me Sh

D006689

Omim

236000

Umls

C0019829C0152266C0152267C1266194C1334968C2239290

Icd10

C81C81.0C81.2C81.3C81.4C81.9

Sym Map

SMDE09515SMDE09516SMDE09517SMDE10590SMDE11048SMDE11502

Do Class

DOID:14566DOID:7

Dis Ge Net

C0019829C0152266C0152267C0220597C1266194C1334968C2239290

Umls Sty

T191

Hpo Class

HP:0001871HP:0002664

Me Sh Class

C04C15C20

Tcmbank Disease

1286624802273394183447758396615

Itcmdb Generated

ITX-DISEASE-3AC5AE444494ITX-DISEASE-97943432965B

Attributes

Merged source attributes and domain-specific metadata.

Version

Suppress

Do Class Name

disease of anatomical entity; disease of cellular proliferation

Disease Type

disease

Hpo Class Name

Neoplasm; Abnormality of blood and blood-forming tissues

Do Disease Class

disease of anatomical entity; disease of cellular proliferation

Hpo Disease Class

Abnormality of blood and blood-forming tissues; Neoplasm

Umls Disease Type

Neoplastic Process

Disease Definition

NCI2016_02D:A diffuse subtype of classical Hodgkin lymphoma which is rich in Hodgkin and Reed-Sternberg cells and/or depleted in non-neoplastic lymphocytes. (WHO, 2008)NCI2016_02D:A subtype of classical Hodgkin lymphoma with scattered Hodgkin and Reed-Sternberg cells and a nodular or less often diffuse cellular background consisting of small lymphocytes and with an absence of neutrophils and eosinophils. (WHO, 2008)NCI2016_02D:A subtype of classical Hodgkin lymphoma with scattered Reed-Sternberg and Hodgkin cells in a diffuse or vaguely nodular mixed inflammatory background without nodular sclerosing fibrosis. (WHO, 2008)NCI2016_NCI-GLOSS_1602D:A rare type of Hodgkin lymphoma, which is a cancer of the immune system. It is marked by the presence of a type of cell called a popcorn cell, which is different from the typical Reed-Sternberg cell found in classical Hodgkin lymphoma. This type of Hodgkin lymphoma may change into diffuse large B-cell lymphoma.|NCI2016_02D:A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)NCI2016_NICHD_1602D:A malignant neoplasm of the lymphatic system that is comprised of abnormal lymphocytes and is characterized by the presence of Reed-Sternberg cells.|NCI2016_NCI-GLOSS_1602D:A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin lymphoma are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats.|NCI2016_02D:An obsolete term referring to Hodgkin lymphoma.|NCI2016_02D:A lymphoma, previously known as Hodgkin's disease, characterized by the presence of large tumor cells in an abundant admixture of nonneoplastic cells. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma involves primarily lymph nodes.|MSH2017_2016_08_12:A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.|MEDLINEPLUS_20151021:Hodgkin disease is a type of lymphoma. <a href='https://www.nlm.nih.gov/medlineplus/lymphoma.html'>Lymphoma</a> is a cancer of a part of the immune system called the lymph system. The first sign of Hodgkin disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver, or bone marrow. The exact cause is unknown. Hodgkin disease is rare. Symptoms include <ul> <li>Painless swelling of the lymph nodes in the neck, armpits, or groin </li> <li>Fever and chills </li> <li>Night sweats </li> <li>Weight loss </li> <li>Loss of appetite </li> <li>Itchy skin</li> </ul> To diagnose Hodgkin disease, doctors use a physical exam and history, blood tests, and a biopsy. Treatment depends on how far the disease has spread. It often includes radiation therapy or chemotherapy. The earlier the disease is diagnosed, the more effective the treatment. In most cases, Hodgkin disease can be cured. NIH: National Cancer Institute|HPO2016_07_04:A typer of lymphoma characterized microscopically by multinucleated Reed-Sternberg cells. [HPO:probinson]|CSP2006:malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue, and the presence of large, usually multinucleate, cells (Reed-Sternberg cells) of unknown origin.

Me Sh Disease Class

Immune System Diseases; Neoplasms; Hemic and Lymphatic Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases

Umls Semantic Type Name

Neoplastic Process