DiseaseID 4158
血管瘤
disease
A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presenting
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Disease: 1Herb: 2Symptom: 12Target: 24Links: 38
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 4158
- Core Entity Id
- 60464
- Source Entity Count
- 1
- Preferred Name
- Angioma
- Name Cn
- 血管瘤
- Name Pinyin
- Xue Guan Liu
- Name En
- Angioma
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Congenital Abnormality
- Disgenet Type
- disease
- Mesh Class
- Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and AbnormalitiesCardiovascular Diseases; Neoplasms; Hemic and Lymphatic DiseasesNeoplasmsNervous System Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsSkin and Connective Tissue Diseases; Congenital, Hereditary, and Neonatal Diseases and AbnormalitiesSkin and Connective Tissue Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsSkin and Connective Tissue Diseases; NeoplasmsSkin and Connective Tissue Diseases; Pathological Conditions, Signs and Symptoms
- Do Class
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferationdisease of anatomical entity; syndromesyndrome
- Hpo Class
- Abnormality of prenatal development or birth; NeoplasmAbnormality of the integumentNeoplasm; Abnormality of the cardiovascular system
- Mesh Class Name
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic Diseases; Cardiovascular DiseasesNeoplasms; Skin and Connective Tissue DiseasesPathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
- Hpo Class Name
- Abnormality of prenatal development or birth; NeoplasmAbnormality of the integumentNeoplasm; Abnormality of the cardiovascular system
- Do Class Name
- disease of anatomical entitydisease of anatomical entity; disease of cellular proliferationdisease of anatomical entity; syndromesyndrome
- Disease Definition
- A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presenting
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Angioma
Role
preferred
Name
Capillary Malformation (Disorder)
Role
preferred
Name
Capillary Malformations, Congenital
Role
preferred
Name
Familial Multiple Nevi Flammei
Role
preferred
Name
Hemangioma
Role
preferred
Name
Hemangioma, Cavernous
Role
preferred
Name
Hemangioma, Intramuscular
Role
preferred
Name
Histiocytoid Hemangioma
Role
preferred
Name
Nevi Flammei, Familial Multiple
Role
preferred
Name
Port-Wine Stain
Role
preferred
Name
Strawberry Nevus Of Skin
Role
preferred
Name
Angioma, Cavernous
Role
preferred
Name
Birthmark
Role
preferred
Name
Cafe-Au-Lait Spots
Role
preferred
Name
Chorioangioma
Role
preferred
Name
Congenital Melanocytic Nevus
Role
preferred
Name
Epithelioid And Spindle Cell Nevus
Role
preferred
Name
GIANT PIGMENTED HAIRY NEVUS
Role
preferred
Name
Inflammatory Linear Verrucous Epidermal Nevus
Role
preferred
Name
Large Congenital Melanocytic Nevus
Role
preferred
Name
Linear Verrucous Epidermal Nevus
Role
preferred
Name
NEVUS, EPIDERMAL (disorder)
Role
preferred
Name
Nevus Comedonicus Syndrome
Role
preferred
Name
Nevus Sebaceous
Role
preferred
Name
Nevus Sebaceus of Jadassohn
Role
preferred
Name
Nevus Spilus
Role
preferred
Name
Nevus, Epidermal
Role
preferred
Name
Nevus, Keratinocytic, Nonepidermolytic
Role
preferred
Name
Organoid Nevus Phakomatosis
Role
preferred
Name
Verrucous Epidermal Nevus
Role
preferred
Name
Woolly Hair Nevus
Role
preferred
Name
Angiolymphoid Hyperplasia With Eosinophilia
Role
alias
Name
CAPILLARY MALFORMATIONS
Role
alias
Name
CMAL
Role
alias
Name
CMC
Role
alias
Name
Cafe Au Lait Spots
Role
alias
Name
Cafe-Au-Lait Macule
Role
alias
Name
Cafe-Au-Lait Macules
Role
alias
Name
Cafe-Au-Lait Spot
Role
alias
Name
Capillary Hemangioma
Role
alias
Name
Capillary Malformation
Role
alias
Name
Capillary Malformations, Congenital, 1
Role
alias
Name
Cavernous Angioma
Role
alias
Name
Cavernous Haemangioma
Role
alias
Name
Cavernous Hemangioma
Role
alias
Name
Chorangioma
Role
alias
Name
Collection of Dilated Blood Vessels That Forms Mass
Role
alias
Name
Congenital Giant Melanocytic Nevus
Role
alias
Name
Epidermal Nevi
Role
alias
Name
Epidermal Nevus
Role
alias
Name
Epithelioid Hemangioma
Role
alias
Name
Familial Multiple Port-wine Stains
Role
alias
Name
Giant Pigmented Mole
Role
alias
Name
Giant Pigmented Nevus
Role
alias
Name
Haemangioma, Any Site
Role
alias
Name
Hemangioma, Capillary
Role
alias
Name
Hemangioma, Histiocytoid
Role
alias
Name
Hemangiomata
Role
alias
Name
Inflammatory Linear Verrucous Epidermal Naevus
Role
alias
Name
Intramuscular Hemangioma
Role
alias
Name
Linear Nevus Sebaceous
Role
alias
Name
Linear Nevus Sebaceous Syndrome
Role
alias
Name
Melanocytic Nevus Syndrome, Congenital
Role
alias
Name
Naevus Sebaceous
Role
alias
Name
Nevus Flammeus
Role
alias
Name
Nevus Simplex
Role
alias
Name
Nevus Spillus
Role
alias
Name
Nevus, Epithelioid And Spindle Cell
Role
alias
Name
Nevus, Sebaceous of Jadassohn
Role
alias
Name
Nevus, Spindle Cell And Epithelioid
Role
alias
Name
Nevus, Woolly Hair
Role
alias
Name
Organoid Nevus
Role
alias
Name
Schimmelpenning-Feuerstein-Mims Syndrome
Role
alias
Name
Sebaceous Mole
Role
alias
Name
Sebaceous Naevus
Role
alias
Name
Sebaceous Nevus
Role
alias
Name
Speckled Lentiginous Nevus
Role
alias
Name
Spitz Nevus
Role
alias
Name
Strawberry Birthmark
Role
alias
Name
Strawberry Mark
Role
alias
Name
Verrucous Nevus
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0000957HP:0001028HP:0001048HP:0001052HP:0005306HP:0005600HP:0010815HP:0010816HP:0010817HP:0025104HP:0025510HP:0032060HP:0100883
Herb
HBDIS001283HBDIS001284HBDIS004300HBDIS004301HBDIS004459HBDIS004464HBDIS004616HBDIS005000HBDIS005816HBDIS005909HBDIS007454HBDIS007864HBDIS008131HBDIS008327HBDIS008525HBDIS009631HBDIS010504HBDIS013481HBDIS015902HBDIS018594HBDIS018595HBDIS020201HBDIS020957HBDIS022634HBDIS022975HBDIS027400
Me Sh
D006391D006392D018324D018332D019080D019339D054000
Omim
137550162900163200
Umls
C0018916C0018920C0205788C0205789C0206733C0235752C0265987C0334082C0340803C0343114C1318558C1842036C2931029C4011754
Icd10
D18.0D18.00L81.3Q82.5
Med Dra
1006719310072036
Sym Map
SMDE01260SMDE01545SMDE02142SMDE02203SMDE03746SMDE06723SMDE07472SMDE09028SMDE09275SMDE09276SMDE09278SMDE09492SMDE11471SMDE11474SMDE11651SMDE12324SMDE13674
Do Class
DOID:14566DOID:225DOID:7
Dis Ge Net
C0018916C0018920C0205788C0205789C0206733C0206739C0221263C0235752C0265329C0265974C0334082C0340803C0343114C0346099C0362030C0473574C0677608C1318558C1842036C1959588C1959589C2931029C3179502C3854181C4011754C4552097
Orphanet
62462664754
Umls Sty
T019T033T047T191
Hpo Class
HP:0001197HP:0001574HP:0001626HP:0002664
Me Sh Class
C04C10C14C15C16C17C23
Etcm Disease
Capillary Malformations, Congenital
Tcmbank Disease
101241095412082138151401153701811619283192851982120832219892357825502551626485280862824628672295832967030926310025469660367779341
Itcmdb Generated
ITX-DISEASE-4B8B0B33ADC8ITX-DISEASE-69C56B4DB8C1ITX-DISEASE-77706416F878ITX-DISEASE-A36EAAA05105ITX-DISEASE-E6E11912C2F5ITX-DISEASE-ECD37288AFDD
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v1,v2v2
Suppress
0
Page Title
Disease Capillary Malformations, Congenital Details page
Do Class Name
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferationdisease of anatomical entity; syndromesyndrome
Disease Type
diseasephenotype
Hpo Class Name
Abnormality of prenatal development or birth; NeoplasmAbnormality of the integumentNeoplasm; Abnormality of the cardiovascular system
Do Disease Class
disease of anatomical entitydisease of anatomical entity; disease of cellular proliferationdisease of anatomical entity; syndromesyndrome
Hpo Disease Class
Abnormality of prenatal development or birth; NeoplasmAbnormality of the integumentNeoplasm; Abnormality of the cardiovascular system
Umls Disease Type
Congenital AbnormalityDisease or SyndromeFindingNeoplastic Process
Basic Information
Disease Name
Capillary Malformations, Congenital
Global Category
Fetal diseases;Genetic diseases;Rare diseases
Anatomical Category
Cardiovascular diseases;Skin diseases
Disease Definition
A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presentingFamilial multiple nevi flammei is a rare, genetic capillary malformation characterized by dark red to purple birthmarks which manifest as flat, sharply circumscribed cutaneous lesions, typically situaNCI2016_02D:A benign, pigmented skin growth caused by an overgrowth of the epidermis. It is typically seen at birth, but can develop in early childhood or later in life. Most cases are sporadic, but familial patterns of inheritance have been observed.|HPO2016_07_04:Epidermal naevi are due to an overgrowth of the epidermis and may be present at birth (50%) or develop during childhood. [HPO:probinson]NCI2016_02D:A common hemangioma characterized by the presence of capillary-sized vascular channels without prominent epithelioid endothelial cells.|NCI2016_02D:A capillary hemangioma that may regress spontaneously. It occurs in infants and children.|MSH2017_2016_08_12:A dull red, firm, dome-shaped hemangioma, sharply demarcated from surrounding skin, usually located on the head and neck, which grows rapidly and generally undergoes regression and involution without scarring. It is caused by proliferation of immature capillary vessels in active stroma, and is usually present at birth or occurs within the first two or three months of life. (Dorland, 27th ed)|HPO2016_07_04:The presence of a capillary hemangiomas, which are hemangiomas with small endothelial spaces. [HPO:probinson]NCI2016_02D:A congenital vascular malformation in the skin (birthmark) characterized by the presence of dilated capillaries. The affected area of the skin is flat and reddish-purplish in color.|MSH2017_2016_08_12:A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483)|HPO2016_07_04:A congenital vascular malformation consisting of superficial and deep dilated capillaries in the skin which produce a reddish to purplish discolouration of the skin. [HPO:sdoelken]NCI2016_02D:A hamartomatous skin lesion containing sebaceous glands. It is usually located in the scalp.|MSH2017_2016_08_12:A syndrome characterized by lesions occurring on the face, scalp, or neck which consist of congenital hypoplastic malformations of cutaneous structures and which over time undergo verrucous hyperplasia. Additionally it is associated with neurological symptoms and skeletal, ophthalmological, urogenital, and cardiovascular abnormalities.|JABL99:A neurocutaneous disorder in which epidermal nevi are associated with multiple anomalies affecting mainly the central nervous and skeletal systems. The nevi are generally present at birth and subsequently undergo pigmentary and verrucous changes, having special predilection for the face and scalp and extending to other organs. Seizures and mental retardation complicate the neurological abnormalities. Hemimegaloencephaly with ipsilateral gyral malformations, seizures, infantile spasms, facial hemihypertrophy, and Dandy-Walker malformation (absence of the cerebellar vermis, hydrocephalus, and posterior fossa cyst continuing with the fourth ventricle) occur in some cases.|HPO2016_07_04:A type of nevus sebaceous with a linear form, raised borders and yellowish color. [HPO:probinson]|HPO2016_07_04:A congenital, hairless plaque consisting of overgrown epidermis, sebaceous glands, hair follicles, apocrine glands and connective tissue. They are a variant of epidermal naevi. Sebaceous naevi most often appear on the scalp, but they may also arise on the face, neck or forehead. At birth, a sevaceous nevus typically appears as a solitary, smooth, yellow-orange hairless patch. Sebaceous naevi become more pronounced around adolescence, often appearing bumpy, warty or scaly. [HPO:probinson]NCI2016_02D:A hemangioma arising from skeletal muscle.NCI2016_02D:A hemangioma characterized by the presence of cavernous vascular spaces.|MSH2017_2016_08_12:A vascular anomaly that is a collection of tortuous BLOOD VESSELS and connective tissue. This tumor-like mass with the large vascular space is filled with blood and usually appears as a strawberry-like lesion in the subcutaneous areas of the face, extremities, or other regions of the body including the central nervous system.|HPO2016_07_04:The presence of a cavernous hemangioma. A hemangioma characterized by large endothelial spaces (caverns) is called a cavernous hemangioma. [HPO:probinson]NCI2016_02D:A hemangioma characterized by the presence of epithelioid endothelial cells.NCI2016_02D:A melanocytic nevus that is present at birth. It may present as a small macular, papular, or plaque-like lesion or as a large brown to black hairy skin lesion.NCI2016_02D:A rare developmental skin condition consisting of abnormal pilosebaceous follicle development. It is characterized by linear or band-like distributions of groups of comedones, usually on the face, neck, upper arm, chest, and abdomen, that appear at birth or in childhood.NCI2016_02D:A rare melanocytic lesion occurring at birth, comprising at least 5% of the body surface area. It usually presents as a dark brown to black hairy lesion. Morphologically, it is characterized by the presence of a compound or intradermal nevus. There is an increased risk of malignant transformation to melanoma, rhabdomyosarcoma, and poorly differentiated malignant tumors.|HPO2016_07_04:The giant congenital nevus is greater than 8 cm in size, pigmented and often hairy. A giant congenital nevus is smaller in infants and children, but it usually continues to grow with the child. [HPO:probinson, pmid:21139903]NCI2016_NICHD_1602D:A benign, vascular neoplasm characterized by the formation of capillary-sized vascular channels.|NCI2016_CDISC_1602D:A benign vascular neoplasm characterized by the formation of capillary-sized or cavernous vascular channels.|NCI2016_02D:A benign vascular lesion characterized by the formation of capillary-sized or cavernous vascular channels.|MSH2017_2016_08_12:A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)|HPO2016_07_04:A hemangioma is a benign tumor characterized by blood-filled spaces lined by benign endothelial cells. A hemangioma characterized by large endothelial spaces (caverns) is called a cavernous hemangioma (in contrast to a hemangioma with small endothelial spaces, which is called capillary hemangioma). [HPO:probinson]|CSP2006:extremely common benign tumor, occurring most commonly in infancy and childhood, made up of newly formed blood vessels, and resulting from malformation of angioblastic tissue of fetal life; can occur anywhere in the body but is most frequently noticed in the skin and subcutaneous tissues.|CHV2011_02:a benign tumor of the blood vessels that appears on skin|CHV2011_02:a benign tumor of the blood vessels that appears on skin|CHV2011_02:a benign tumor of the blood vessels that appears on skin|CHV2011_02:a benign tumor of the blood vessels that appears on skin|CHV2011_02:A benign skin lesion consisting of dense, usually elevated masses of dilated blood vessels|CHV2011_02:A benign skin lesion consisting of dense, usually elevated masses of dilated blood vessels|CHV2011_02:A benign skin lesion consisting of dense, usually elevated masses of dilated blood vessels
Me Sh Disease Class
Cardiovascular Diseases; Congenital, Hereditary, and Neonatal Diseases and AbnormalitiesCardiovascular Diseases; Neoplasms; Hemic and Lymphatic DiseasesNeoplasmsNervous System Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsSkin and Connective Tissue Diseases; Congenital, Hereditary, and Neonatal Diseases and AbnormalitiesSkin and Connective Tissue Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; NeoplasmsSkin and Connective Tissue Diseases; NeoplasmsSkin and Connective Tissue Diseases; Pathological Conditions, Signs and Symptoms
Dis Ge Net Disease Type
diseasephenotype
Disease Class Name Me Sh
Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue DiseasesNeoplasmsNeoplasms; Hemic and Lymphatic Diseases; Cardiovascular DiseasesNeoplasms; Skin and Connective Tissue DiseasesPathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
Umls Semantic Type Name
Congenital AbnormalityDisease or SyndromeFindingNeoplastic Process