DiseaseID 3905
精原细胞瘤
disease
NCI2016_CDISC_1602D:A non-seminomatous malignant germ cell tumor composed of primitive germ cells and which produce an eosinophilic substance (alpha-fetoprotein).|NCI2016_02D:A non-seminomatous malignant germ cell tumor
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Disease: 1Symptom: 2Target: 13Links: 15
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Record Fields
Scalar fields from the final disease record.
- Disease Id
- 3905
- Core Entity Id
- 60172
- Source Entity Count
- 1
- Preferred Name
- Seminoma
- Name Cn
- 精原细胞瘤
- Name Pinyin
- Jing Yuan Xi Bao Liu
- Name En
- Seminoma
- Name Latin
- Bilingual Status
- complete
- Disease Type
- disease
- Umls Disease Type
- Neoplastic Process
- Disgenet Type
- disease
- Mesh Class
- Male Urogenital Diseases; Neoplasms; Endocrine System DiseasesNeoplasms
- Do Class
- disease of anatomical entity; disease of cellular proliferation
- Hpo Class
- Neoplasm; Abnormality of the genitourinary system
- Mesh Class Name
- NeoplasmsNeoplasms; Male Urogenital Diseases; Endocrine System Diseases
- Hpo Class Name
- Abnormality of the genitourinary system; Neoplasm
- Do Class Name
- disease of anatomical entity; disease of cellular proliferation
- Disease Definition
- NCI2016_CDISC_1602D:A non-seminomatous malignant germ cell tumor composed of primitive germ cells and which produce an eosinophilic substance (alpha-fetoprotein).|NCI2016_02D:A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.|MSH2017_2016_08_12:An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
- Version
- v1
- Suppressed
- No
Names
Preferred names, aliases, and source labels retained in the final schema.
Name
Seminoma
Role
preferred
Name
Testicular Germ Cell Tumor
Role
preferred
Name
Yolk Sac Tumor
Role
preferred
Name
EMBRYONAL CELL CARCINOMA
Role
preferred
Name
Nongerminomatous Germ Cell Tumor
Role
preferred
Name
Spermatocytic Seminoma
Role
preferred
Name
Teratoma of Testis
Role
preferred
Name
ENDODERMAL SINUS TUMOR
Role
alias
Name
MALE GERM CELL TUMOR
Role
alias
Name
MGCT
Role
alias
Name
NONSEMINOMATOUS GERM CELL TUMORS
Role
alias
Name
Nonseminomatous Germ Cell Tumor
Role
alias
Name
Spermatocytoma
Role
alias
Name
TERATOMA, TESTICULAR
Role
alias
Name
TGCT
Role
alias
Name
Testicular Germ Cell Cancer
Role
alias
Name
Testicular Seminoma
Role
alias
Name
Testicular Teratoma
Role
alias
Name
Testis Seminoma
Role
alias
Cross References
Trusted external identifiers retained for this final record.
Hpo
HP:0100616HP:0100617
Herb
HBDIS000930HBDIS002713HBDIS005178HBDIS007579HBDIS013000HBDIS013992HBDIS021404
Me Sh
D018239D018240
Umls
C0014145C0036631C0238451C0334517C1266158C1336708C3463918
Sym Map
SMDE03866SMDE13065SMDE14422
Do Class
DOID:14566DOID:7
Dis Ge Net
C0014145C0036631C0238451C0334517C1266158C1336708C3463918
Umls Sty
T191
Hpo Class
HP:0000119HP:0002664
Me Sh Class
C04C12C19
Tcmbank Disease
102471387016007280872813055905784
Itcmdb Generated
ITX-DISEASE-71D341DD8DA4
Attributes
Merged source attributes and domain-specific metadata.
Version
v1v2
Suppress
0
Do Class Name
disease of anatomical entity; disease of cellular proliferation
Disease Type
disease
Hpo Class Name
Abnormality of the genitourinary system; Neoplasm
Do Disease Class
disease of anatomical entity; disease of cellular proliferation
Hpo Disease Class
Neoplasm; Abnormality of the genitourinary system
Umls Disease Type
Neoplastic Process
Disease Definition
NCI2016_CDISC_1602D:A non-seminomatous malignant germ cell tumor composed of primitive germ cells and which produce an eosinophilic substance (alpha-fetoprotein).|NCI2016_02D:A non-seminomatous malignant germ cell tumor composed of primitive germ cells. It is the most common malignant germ cell tumor in the pediatric population. It occurs in the infant testis, ovary, sacrococcygeal region, vagina, uterus, prostate, abdomen, liver, retroperitoneum, thorax, and pineal/third ventricle. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). Treatment includes: surgical resection, radiation, and chemotherapy. This tumor is very responsive to chemotherapy regimens that include cisplatinum.|MSH2017_2016_08_12:An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)NCI2016_NCI-GLOSS_1602D:A type of cancer of the testicles. Seminomas may spread to the lung, bone, liver, or brain.|NCI2016_CDISC_1602D:A malignant germ cell neoplasm of the testis.|NCI2016_02D:A radiosensitive malignant germ cell tumor found in the testis (especially undescended), and extragonadal sites (anterior mediastinum and pineal gland). It is characterized by the presence of uniform cells with clear or dense cytoplasm which contains glycogen, and by a large nucleus which contains one or more nucleoli. The neoplastic germ cells form aggregates separated by fibrous septa. The fibrous septa contain chronic inflammatory cells, mainly lymphocytes.|NCI2016_02D:A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.|MSH2017_2016_08_12:A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)|HPO2016_07_04:The presence of a seminoma, an undifferentiated germ cell tumor of the testis. [HPO:sdoelken]
Me Sh Disease Class
Male Urogenital Diseases; Neoplasms; Endocrine System DiseasesNeoplasms
Dis Ge Net Disease Type
disease
Disease Class Name Me Sh
NeoplasmsNeoplasms; Male Urogenital Diseases; Endocrine System Diseases
Umls Semantic Type Name
Neoplastic Process