DiseaseID 3900

心内膜炎

disease

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Disease: 1Experiment: 10Symptom: 12Target: 12Links: 34

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Record Fields

Scalar fields from the final disease record.

Disease Id: 3900
Core Entity Id: 60166
Source Entity Count: 1
Preferred Name: Endocarditis
Name Cn: 心内膜炎
Name Pinyin: Xin Nei Mo Yan
Name En: Endocarditis
Name Latin
Bilingual Status: complete
Disease Type: disease
Umls Disease Type: Disease or Syndrome
Disgenet Type: disease
Mesh Class: Cardiovascular DiseasesCardiovascular Diseases; InfectionsSkin and Connective Tissue Diseases; Immune System Diseases
Do Class: disease of anatomical entity
Hpo Class: Abnormality of the immune systemAbnormality of the immune system; Abnormality of the cardiovascular system
Mesh Class Name: Cardiovascular DiseasesInfections; Cardiovascular DiseasesSkin and Connective Tissue Diseases; Immune System Diseases
Hpo Class Name: Abnormality of the immune systemAbnormality of the immune system; Abnormality of the cardiovascular system
Do Class Name: disease of anatomical entity
Disease Definition: MSH2017_2016_08_12:Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.|HPO2016_07_04:A bacterial infection of the endocardium, the inner layer of the heart, which usually involves the heart valves. [HPO:sdoelken]|CSP2006:infection occuring when bacteria in the bloodstream (bacteremia) adhere to abnormal heart valves or other damaged heart tissue; characterized by growths, known as vegetations, on the valves or other areas of the heart which can break off, travel to other parts of the body, and cause serious complications; a common causative bacteria is staphylococcus, but any organism entering the bloodstream from any site of prior infection can result in the infection.
Version: v1
Suppressed: No

Names

Preferred names, aliases, and source labels retained in the final schema.

Name

Endocarditis

Role

preferred

Name

Endocarditis, Atypical, Verrucous

Role

preferred

Name

Lupus Erythematosus, Systemic

Role

preferred

Name

Subacute Bacterial Endocarditis

Role

preferred

Name

Systemic Lupus Erythematosus 16

Role

preferred

Name

Acute Endocarditis

Role

preferred

Name

Bacterial Endocarditis

Role

preferred

Name

Infective Endocarditis

Role

preferred

Name

Libman-Sacks Disease

Role

preferred

Name

Acute Endocarditis, Unspecified

Role

alias

Name

Endocarditis, Bacterial

Role

alias

Name

Endocarditis, Infective

Role

alias

Name

Endocarditis, Subacute Bacterial

Role

alias

Name

SLEB16

Role

alias

Name

Systemic Lupus Erythematosus

Role

alias

Name

Systemic Lupus Erythematosus, Unspecified

Role

alias

Cross References

Trusted external identifiers retained for this final record.

Hpo

HP:0002725HP:0006689HP:0100584

Herb

HBDIS000923HBDIS000924HBDIS000925HBDIS001792HBDIS005418HBDIS008541HBDIS014540HBDIS021340

Me Sh

D004696D004697D004698D008180

Omim

152700614420

Umls

C0014118C0014121C0014122C0024141C0242380C3280742

Icd10

I33.9M32M32.11M32.9

Sym Map

SMDE01650SMDE06249SMDE08247SMDE08248SMDE10569SMDE13693

Do Class

DOID:7

Dis Ge Net

C0014118C0014121C0014122C0024141C0242380C0375268C1541923C3280742

Umls Sty

T047

Hpo Class

HP:0001626HP:0002715

Me Sh Class

C01C14C17C20

Tcmbank Disease

124281373172182072232962953375437

Itcmdb Generated

ITX-DISEASE-AD45C89C5865ITX-DISEASE-B842FBDDC3AF

Attributes

Merged source attributes and domain-specific metadata.

Version

v1v2

Suppress

Do Class Name

disease of anatomical entity

Disease Type

disease

Hpo Class Name

Abnormality of the immune systemAbnormality of the immune system; Abnormality of the cardiovascular system

Do Disease Class

disease of anatomical entity

Hpo Disease Class

Abnormality of the immune systemAbnormality of the immune system; Abnormality of the cardiovascular system

Umls Disease Type

Disease or Syndrome

Disease Definition

MSH2017_2016_08_12:Inflammation of the ENDOCARDIUM caused by BACTERIA that entered the bloodstream. The strains of bacteria vary with predisposing factors, such as CONGENITAL HEART DEFECTS; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; or intravenous drug use.|HPO2016_07_04:A bacterial infection of the endocardium, the inner layer of the heart, which usually involves the heart valves. [HPO:sdoelken]|CSP2006:infection occuring when bacteria in the bloodstream (bacteremia) adhere to abnormal heart valves or other damaged heart tissue; characterized by growths, known as vegetations, on the valves or other areas of the heart which can break off, travel to other parts of the body, and cause serious complications; a common causative bacteria is staphylococcus, but any organism entering the bloodstream from any site of prior infection can result in the infection.NCI2016_NICHD_1602D:An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.|NCI2016_NCI-GLOSS_1602D:A chronic, inflammatory, connective tissue disease that can affect many organs including the joints, skin, heart, lungs, kidneys, and nervous system. It is marked by many different symptoms; however, not everyone with SLE has all of the symptoms.|NCI2016_02D:An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.|MSH2017_2016_08_12:A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.|HPO2016_07_04:A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. [HPO:probinson]|CSP2006:chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes; it is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system; the disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.NCI2016_NICHD_1602D:Chronic infection of the endocardium or heart valves.|NCI2016_02D:Subacute inflammation of the endocardium. Streptococcus viridans is the usual etiologic agent of subacute bacterial endocarditis. The distinction between "acute" and "subacute" endocarditis has traditionally been made based on the pathogenic organism and clinical presentation.|MSH2017_2016_08_12:ENDOCARDIUM infection that is usually caused by STREPTOCOCCUS. Subacute infective endocarditis evolves over weeks and months with modest toxicity and rare metastatic infection.NCI2016_NICHD_1602D:Inflammation of the endocardium.|NCI2016_02D:Inflammation of the endocardium.|MSH2017_2016_08_12:Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.|MEDLINEPLUS_20151021:Endocarditis, also called infective endocarditis (IE), is an inflammation of the inner lining of the heart. The most common type, bacterial endocarditis, occurs when germs enter your heart. These germs come through your bloodstream from another part of your body, often your mouth. Bacterial endocarditis can damage your heart valves. If untreated, it can be life-threatening. It is rare in healthy hearts. Risk factors include having <ul> <li>An abnormal or damaged heart valve </li> <li>An artificial heart valve </li> <li><a href='https://www.nlm.nih.gov/medlineplus/congenitalheartdefects.html'>Congenital heart defects</a></li> </ul> The signs and symptoms of IE can vary from person to person. They also can vary over time in the same person. Symptoms you might notice include fever, shortness of breath, fluid buildup in your arms or legs, tiny red spots on your skin, and weight loss. Your doctor will diagnose IE based on your risk factors, medical history, signs and symptoms, and lab and heart tests. Early treatment can help you avoid complications. Treatment usually involves high-dose antibiotics. If your heart valve is damaged, you may need surgery. If you're at risk for IE, brush and floss your teeth regularly, and have regular dental checkups. Germs from a gum infection can enter your bloodstream. If you are at high risk, your doctor might prescribe antibiotics before dental work and certain types of surgery. NIH: National Heart, Lung, and Blood Institute|HPO2016_07_04:An inflammation of the endocardium, the inner layer of the heart, which usually involves the heart valves. [HPO:sdoelken]|CSP2006:exudative and proliferative inflammatory alterations of the endocardium, characterized by the presence of vegetations on the surface of the endocardium or in the endocardium itself, and most commonly involving a heart valve, but sometimes affecting the inner lining of the cardiac chambers or the endocardium elsewhere; may occur as a primary disorder or as a complication of or in association with another disease.

Me Sh Disease Class

Cardiovascular DiseasesCardiovascular Diseases; InfectionsSkin and Connective Tissue Diseases; Immune System Diseases

Dis Ge Net Disease Type

disease

Disease Class Name Me Sh

Cardiovascular DiseasesInfections; Cardiovascular DiseasesSkin and Connective Tissue Diseases; Immune System Diseases

Umls Semantic Type Name

Disease or Syndrome